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Nutrition: Sodium

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Total 46 results found since Jan 2013.

Clinical Efficacy and Short-Term Prognosis of Butylphthalide and Sodium Chloride Injection Compared to Edaravone in the Treatment of Patients with Acute Stroke
CONCLUSIONS: This study highlights the positive impact of butylphthalide and edaravone on the therapeutic effect and short-term prognosis in acute stroke patients. The findings provide valuable guidance for future research and enhance our understanding of these drugs' mechanisms, offering the potential for improved stroke management and patient outcomes.PMID:37499159
Source: Alternative Therapies in Health and Medicine - July 27, 2023 Category: Complementary Medicine Authors: Dan Yang Mi Zhang Xiaoyan Wang Jianna Zhang Source Type: research

Burden and attributable risk factors of ischemic stroke in China from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019
ConclusionOur study revealed that great changes have occurred in burden and attributable risk factors of ischemic stroke in China in the past three decades. Distinct sex-specific differences are observed in burden and attributable risk factors.
Source: Frontiers in Neurology - July 26, 2023 Category: Neurology Source Type: research

How to Tell The Difference Between Heat Stress, Exhaustion, and Stroke
The terminology around heat injuries and illness is often confusing. As extreme heat warnings sweep the U.S., here is what you need to know about heat stress, heat exhaustion, and heat stroke. A 90°F-day might be perfect for the beach. But once you start working your body, whether it’s mowing the lawn, going for a hike, or sprinting to catch the bus, your metabolism ramps up, burning fuel and raising your body’s core temperature. Your heart compensates by pumping blood away from your overheated organs to your skin, where dilating blood vessels can dissipate the heat with the help of evaporating sweat. If yo...
Source: TIME: Health - July 18, 2023 Category: Consumer Health News Authors: Aryn Baker Tags: Uncategorized Climate Is Everything Explainer extreme weather healthscienceclimate Source Type: news

New VOYAGER PAD Analysis Confirms Consistent Benefit of XARELTO ® (rivaroxaban) Plus Aspirin Following Lower Extremity Revascularization (LER)
TITUSVILLE, NJ, March 5, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from a new prespecified analysis from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefits of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) over standard of care (aspirin alone), demonstrating consistent benefit at 30 days, 90 days and up to three years following LER in patients with PAD. Lower extremity revascularization, also called peripheral revascularization, is a procedure that restores blood flow in blocked arteries or veins. This analysis of ...
Source: Johnson and Johnson - March 5, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

The role of blood pressure management in stroke prevention: current status and future prospects
Expert Rev Cardiovasc Ther. 2022 Oct 16. doi: 10.1080/14779072.2022.2137490. Online ahead of print.ABSTRACTINTRODUCTION: Stroke is the second-leading cause of death worldwide and the second-leading cause of disability-adjusted life-years. It is well-known that hypertension is a significant risk factor for cardiovascular events, including stroke.AREAS COVERED: Recent interventional trials have demonstrated the superiority of intensive blood pressure (BP) control for prevention of cardiovascular events compared to standard BP control. Notably, in the Strategy of Blood Pressure Intervention in Elderly Hypertensive Patients (S...
Source: Expert Review of Cardiovascular Therapy - October 17, 2022 Category: Cardiology Authors: Keisuke Narita Satoshi Hoshide Kazuomi Kario Source Type: research

Determination of 23 related analytes in bone marrow fluid and hippocampus of C57BL/6 mice on cerebral ischemia-reperfusion injury by HPLC-FLD
Biomed Chromatogr. 2022 Jun 28:e5435. doi: 10.1002/bmc.5435. Online ahead of print.ABSTRACTThe study of brain diseases has long been of interest to researchers worldwide, and stroke is the third leading cause of death that threatens human health. At the same time, a cerebral ischemia-reperfusion injury is closely associated with high rates of disability and mortality. The conditions of the 6-Aminoquinolyl N-hydroxysccinimidyl carbamate (AQC) method for the derivatization of amino acids in the bone marrow fluid and hippocampus of C57BL/6 mice with cerebral ischemia/reperfusion injury were explored and optimized, such as the...
Source: Biomedical Chromatography : BMC - June 28, 2022 Category: Biomedical Science Authors: Jing Zhang Junqing Yang Ying Luo Jiansha Li Tao Gong Suqiong Huang Yan Xiong Xinhui Jiang Source Type: research

The crosstalk signals of Sodium Tanshinone ⅡA Sulfonate in rats with cerebral ischemic stroke: Insights from proteomics
CONCLUSIONS: We concluded that STS could prevent penumbra from progressively ongoing damage and improve neurological deficits in MCAO/R model rats. The intersected pathways and protein networks predicted by proteomics might provide much more detailed information for the therapeutic mechanisms of STS in the treatment of CIS.PMID:35561426 | DOI:10.1016/j.biopha.2022.113059
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - May 13, 2022 Category: Drugs & Pharmacology Authors: Zheyi Wang Yize Sun Lihua Bian Yiling Zhang Yue Zhang Chunguo Wang Jinzhou Tian Tao Lu Source Type: research

Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential Nrf2 activators for the treatment of cerebral ischemic injury
Eur J Med Chem. 2022 Mar 28;236:114315. doi: 10.1016/j.ejmech.2022.114315. Online ahead of print.ABSTRACTAcute ischemic stroke is a leading cause of disability and death. The development of neuroprotectants is an emerging strategy for the treatment of ischemic stroke. In this work, we designed and synthesized a series of 1,3,5-triaryl substituent triazole derivatives by introducing a phenolic group and phenyl ring to 3,5-diaryl substituents oxadiazole. Structure-activity relationship (SAR) analysis showed that compounds with alkyl groups or with substituents at the 3-position possessed better protective effects. Among the ...
Source: European Journal of Medicinal Chemistry - April 7, 2022 Category: Chemistry Authors: Yaoqiang Lao Yang Wang Jianwen Chen Ping Huang Ruiqi Su Jinguo Shi Caibao Jiang Jingxia Zhang Source Type: research