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Specialty: Neurology
Condition: Pregnancy
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Total 194 results found since Jan 2013.
Endovascular Treatment and Peri-interventional Management of Ruptured Cerebrovascular Lesions During Pregnancy
ConclusionEndovascular treatment of ruptured cerebrovascular malformations during pregnancy is safe and feasible regarding both aspects, the maternal and fetal outcomes. Still, a stronger knowledge base is needed to correctly approach future cases of intracranial hemorrhage in the pregnant population.
Source: Clinical Neuroradiology - September 1, 2023 Category: Neurology Source Type: research
Factors influencing real-life use of direct oral anticoagulants in patients with cerebral sinus and venous thrombosis
Cerebral sinus and venous thrombosis (CSVT) is a rare subtype of stroke caused by thrombosis of the dural sinuses and cerebral veins which comprises 0.5 –1% of all strokes1,2. The annual incidence ranges from 0.22 to 1.57 per 100,000, most often affecting young adults with a median age of 35 years3-5. Among CSVT patients, the female-to-male ratio is 3:1 and women are significantly younger compared to men6. This is largely due to the increased risk of CSVT associated with oral contraceptives, pregnancy and the puerperium3,7,8.
Source: Journal of Stroke and Cerebrovascular Diseases - July 10, 2023 Category: Neurology Authors: Naaem Simaan, Jeremy Molad, Asaf Honig, Andrei Filioglo, Shlomi Peretz, Fadi Shbat, Tarek Mansor, Waleed Abu-shaheen, Ronen R. Leker Source Type: research
COVID-19 and Cerebrovascular Disease
This article discusses the incidence of these cerebrovascular complications, risk factors, management strategies, prognosis and future research directions, as well as considerations in pregnancy-related cerebrovascular events in the setting of COVID-19. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Seminars in Neurology - May 22, 2023 Category: Neurology Authors: Catherine, Christina Veitinger, Julia Chou, Sherry H-Y. Tags: Review Article Source Type: research
Letter to the Editor Regarding ‘A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID19 infection during pregnancy: cause or coincidence?’
We read with interest the article by Ozdil et al. about a three day-old female neonate who was diagnosed with venous sinus thrombosis (VST) which was complicated by a subacute, partial ischemic stroke in the territory of the right middle cerebral artery.1 The age of the stroke was estimated at 14-28 days before birth.1 Because the mother suffered a mild coronvirus disease-19 (COVID-19) infection during the initial weeks of the third trimester (gestational weeks 27-30), VST in the fetus was causally related to the severe, acute respiratory syndrome-coronavirus type-2 (SARS-CoV-2) infection of the mother.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2023 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research
Women's reproductive traits and cerebral small-vessel disease: A two-sample Mendelian randomization study
ConclusionOur findings do not convincingly support a causal effect of women's reproductive factors on CSVD. Future studies are warranted to investigate specific estrogen-related physiological changes in women, which may inform current researchers on the causal mechanisms involved in cerebral small-vessel disease progression.
Source: Frontiers in Neurology - March 30, 2023 Category: Neurology Source Type: research
Impact of hypertensive disorders of pregnancy on short- and long-term outcomes of pregnancy-associated hemorrhagic stroke
ConclusionsIn this retrospective study, women with hypertension disorders of pregnancy did not show worse short-term outcomes of pregnancy-associated hemorrhagic stroke compared to those without but had poorer long-term functional outcomes. This underlines the importance of prevention, recognition, and treatment of hypertension disorders in these women.
Source: Frontiers in Neurology - March 16, 2023 Category: Neurology Source Type: research
In Reply to the Letter to the Editor Regarding "A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID-19 infection during pregnancy: Cause or coincidence?"
We are grateful to Josef Finsterer for his comments on our recent case regarding the possible association of maternal COVID-19 infection during pregnancy with a neonatal case of intrauterine cerebral sinus venous thrombosis (CSVT). In the letter to editor, he had raised several arguments against a causal relationship, however our case report focused on the plausability of maternal COVID-19 infection as a triggering factor for in utero onset of CVST.
Source: Journal of Stroke and Cerebrovascular Diseases - March 6, 2023 Category: Neurology Authors: Dr Mine Ozdil, Dr İpek Dokurel Cetin Tags: Letter to the Editor Source Type: research
APRIL: A double-blind, placebo-controlled, randomized, Phase Ib/IIa clinical study of ApTOLL for the treatment of acute ischemic stroke
In the reperfusion era, a new paradigm of treating patients with endovascular treatment (EVT) and neuroprotective drugs is emerging as a promising therapeutic option for patients with acute ischemic stroke (AIS). In this context, ApTOLL, a Toll-like receptor 4 (TLR4) antagonist with proven neuroprotective effect in preclinical models of stroke and a very good pharmacokinetic and safety profile in healthy volunteers, is a promising first-in-class aptamer with the potential to address this huge unmet need. This protocol establishes the clinical trial procedures to conduct a Phase Ib/IIa clinical study (APRIL) to assess ApTOL...
Source: Frontiers in Neurology - February 24, 2023 Category: Neurology Source Type: research
The landscape of disparities in obstetric neurocritical care and a path forward
Health disparities in the obstetric population affect maternal morbidity and mortality. In the past years, there has been no significant improvement in disparities in care in the obstetric population. Patients who are pregnant are known to have a higher risk of pregnancy-associated neurologic conditions such as stroke and intracerebral hemorrhage. They can also experience concomitant neurocritical care disease states such as status epilepticus and traumatic brain injury. Studies exploring the disparities of care among pregnant patients who are neurotically ill are lacking. We aim to provide the landscape of disparities of ...
Source: Frontiers in Neurology - January 6, 2023 Category: Neurology Source Type: research
A neonatal case of cerebral venous thrombosis with intrauterine onset after COVID19 infection during pregnancy: cause or coincidence?
Coronavirus 19 disease (COVID-19) is known to predispose patients to increased thrombotic events and the risk is higher in pregnancy which is already a hypercoagulable state. Vertical transmission of the disease during pregnancy was neglected according to data early in the pandemic, however, despite conflicting results from different studies, there is an increasing suspicion of vertical transmission with the rise of new fetal and neonatal cases and perinatal transmission can be higher than expected.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2022 Category: Neurology Authors: Mine Ozdil, İpek Dokurel Cetin Tags: Case Report Source Type: research
A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID-19 infection during pregnancy: Cause or coincidence?
Coronavirus 19 disease (COVID-19) is known to predispose patients to increased thrombotic events and the risk is higher in pregnancy which is already a hypercoagulable state. Vertical transmission of the disease during pregnancy was neglected according to data early in the pandemic, however, despite conflicting results from different studies, there is an increasing suspicion of vertical transmission with the rise of new fetal and neonatal cases and perinatal transmission can be higher than expected.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2022 Category: Neurology Authors: Mine Ozdil, Ipek Dokurel Cetin Tags: Case Report Source Type: research
Clinical Features and Risk Factors of Mortality in Patients with Posterior Reversible Encephalopathy Syndrome
CONCLUSIONS: Our results indicate that PRES could be considered as a sign of a very high-risk patient. We also demonstrated that heart failure and stroke were independent risk factors for death in patients with PRES; moreover, pregnancy was a protective factor.PMID:36419591 | PMC:PMC9678458 | DOI:10.1155/2022/9401661
Source: Behavioural Neurology - November 24, 2022 Category: Neurology Authors: Hong-Wei Cui Ru-Yi Lei Bo-Ai Zhang Source Type: research
