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Source: International Journal of Cardiology
Condition: Atrial Fibrillation
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Total 388 results found since Jan 2013.
‘Some doors are better left closed’: Using LAA occluders as an alternative to warfarin in very high-risk dialysed patients with atrial fibrillation
Since 2011, when the EMA approved the treatment with novel oral anticoagulants (NOACs) for primary prevention of cardio-embolic stroke in patients with atrial fibrillation (AF), a reasonable question repeatedly arose: “Will NOACs become the new standard of care in anticoagulation therapy?” [1]. While for many cathegories of patients the answer soon become positive [2], the sub-group of advanced chronic kidney disease (CKD) 5D stage (in dialysis) has never received a “yes” from either FDA or EMA (none of t hem allowing the use of NOACs in 5D CKD).
Source: International Journal of Cardiology - April 27, 2018 Category: Cardiology Authors: Alexandru Burlacu, Adrian Covic Tags: Editorial Source Type: research
Disentangling the risk of atrial fibrillation detected after ischemic stroke (AFDAS): A real challenge in clinical practice
Atrial fibrillation (AF) can be newly-diagnosed in up to 24% of patients with ischemic stroke [1]. The entity so called “AF detected after stroke” (AFDAS) has been created to acknowledge the complexity of diagnosing and managing these patients [2]. AFDAS may be a pre-existing AF condition that is unknown and/or asymptomatic, and is only diagnosed because of thorough post-stroke electrocardiographic monitoring in a yet unknown proportion of patients. Conversely, it may also be the consequence of neurogenic AF mechanisms triggered by the presence of a stroke.
Source: International Journal of Cardiology - April 26, 2018 Category: Cardiology Authors: Luciano A. Sposato, Renato D. Lopes Tags: Editorial Source Type: research
Characteristics and outcomes of ischemic stroke in patients with known atrial fibrillation or atrial fibrillation diagnosed after stroke
It is unclear whether ischemic stroke patients with known atrial fibrillation (KAF) had different outcomes than those with atrial fibrillation diagnosed after stroke (AFDAS). We aimed to explore the characteristics and outcomes in ischemic stroke patients with KAF or AFDAS.
Source: International Journal of Cardiology - April 26, 2018 Category: Cardiology Authors: Cheng-Yang Hsieh, Cheng-Han Lee, Darren Philbert Wu, Sheng-Feng Sung Source Type: research
Different safety profiles of oral anticoagulants in very elderly non-valvular atrial fibrillation patients: A retrospective propensity score matched cohort study
Vitamin K antagonists (VKAs) have been shown to decrease the risk of ischemic stroke and systemic embolism in patients with non-valvular atrial fibrillation (NVAF). [1] The non-VKA oral anticoagulants (NOACs) are now increasingly used as an alternative to VKAs thanks to their convenient, fixed dose and no requirement for monitoring. NOACs have shown non-inferiority to warfarin for the prevention of stroke and systemic embolism, with marked reduction in the risk of intracerebral haemorrhage [2].
Source: International Journal of Cardiology - April 25, 2018 Category: Cardiology Authors: Giacomo Zoppellaro, Luca Zanella, Gentian Denas, Nicola Gennaro, Eliana Ferroni, Ugo Fedeli, Seena Padayattil Jose, Giorgio Costa, Maria Chiara Corti, Margherita Andretta, Vittorio Pengo Source Type: research
Increased risk of ischemic stroke associated with new-onset atrial fibrillation complicating acute coronary syndrome: A systematic review and meta-analysis
Atrial fibrillation has been established as a major risk factor of ischemic stroke, however, the influence of new-onset atrial fibrillation (NOAF) complicating acute coronary syndrome (ACS) on ischemic stroke remains controversial. This meta-analysis aimed to validate the association between NOAF complicating ACS and ischemic stroke.
Source: International Journal of Cardiology - April 23, 2018 Category: Cardiology Authors: Jiachen Luo, Hongqiang Li, Xiaoming Qin, Baoxin Liu, Jinlong Zhao, Guli Maihe, Zhiqiang Li, Yidong Wei Source Type: research
Disentangling the risk of atrial fibrillation detected after ischemic stroke (AFDAS): A real challenge in clinical practice
Atrial fibrillation (AF) can be newly-diagnosed in up to 24% of patients with ischemic stroke [1]. The entity so called “AF detected after stroke” (AFDAS) has been created to acknowledge the complexity of diagnosing and managing these patients [2]. AFDAS may be a pre-existing AF condition that is unknown and/or asymptomatic, and is only diagnosed because of thorough post-stroke electrocardiographic monitoring in a yet unknown proportion of patients. Conversely, it may also be the consequence of neurogenic AF mechanisms triggered by the presence of a stroke.
Source: International Journal of Cardiology - April 13, 2018 Category: Cardiology Authors: Luciano A. Sposato, Renato D. Lopes Tags: Editorial Source Type: research
Characteristics and outcomes of ischemic stroke in patients with known atrial fibrillation or atrial fibrillation diagnosed after stroke
It is unclear whether ischemic stroke patients with known atrial fibrillation (KAF) had different outcomes than those with atrial fibrillation diagnosed after stroke (AFDAS). We aimed to explore the characteristics and outcomes in ischemic stroke patients with KAF or AFDAS.
Source: International Journal of Cardiology - April 13, 2018 Category: Cardiology Authors: Cheng-Yang Hsieh, Cheng-Han Lee, Darren Philbert Wu, Sheng-Feng Sung Source Type: research
Resting heart rate in late adolescence and long term risk of cardiovascular disease in Swedish men
To investigate the association of resting heart rate (RHR) measured in late adolescence with the long term risk of myocardial infarction (MI), ischemic stroke (IS), heart failure (HF), atrial fibrillation (AF), cardiovascular- and all-cause death.
Source: International Journal of Cardiology - March 23, 2018 Category: Cardiology Authors: Martin Lindgren, Josefina Robertson, Martin Adiels, Maria Schaufelberger, Maria Åberg, Kjell Torén, Margda Waern, N. David Åberg, Annika Rosengren Source Type: research
Relationship between CHA2DS2-VASc score, coronary artery disease severity, residual platelet reactivity and long-term clinical outcomes in patients with acute coronary syndrome
The CHA2DS2-VASc score predicts stroke risk in patients with atrial fibrillation, but recently has been reported to have a prognostic role even in patients with ACS. We sought to assess the ability of the CHA2DS2-VASc score to predict the severity of coronary artery disease, high residual platelet reactivity and long-term outcomes in patients with acute coronary syndrome (ACS).
Source: International Journal of Cardiology - March 20, 2018 Category: Cardiology Authors: Fernando Scudiero, Chiara Zocchi, Elena De Vito, Giuseppe Tarantini, Rossella Marcucci, Renato Valenti, Angela Migliorini, David Antoniucci, Niccol ò Marchionni, Guido Parodi Source Type: research
The effectiveness and safety of low-dose rivaroxaban in Asians with non-valvular atrial fibrillation
The objective of the study is to compare the effectiveness and safety of low-dose rivaroxaban to those of warfarin among Asians with NVAF.
Source: International Journal of Cardiology - March 14, 2018 Category: Cardiology Authors: Hsin-Fu Lee, Yi-Hsin Chan, Hui-Tzu Tu, Chi-Tai Kuo, Yung-Hsin Yeh, Shang-Hung Chang, Lung-Sheng Wu, Lai-Chu See Source Type: research
Impact of BMI on clinical outcomes of NOAC therapy in daily care - Results of the prospective Dresden NOAC Registry (NCT01588119)
Direct acting non-Vitamin K antagonist oral anticoagulants (NOAC) are characterized by a fixed dosing regimen. Despite the potential for relative underdosing due to large distribution volumes, dose adjustments for patients with high body mass index (BMI) are not recommended. Since efficacy and safety data in obese patients are scarce, we evaluated the impact of BMI on clinical outcomes in daily care patients treated with NOAC for stroke prevention in atrial fibrillation or venous thromboembolism.
Source: International Journal of Cardiology - March 14, 2018 Category: Cardiology Authors: L. Tittl, S. Endig, S. Marten, A. Reitter, I. Beyer-Westendorf, J. Beyer-Westendorf Source Type: research
The effectiveness and safety of low-dose rivaroxaban in Asians with non-valvular atrial fibrillation
The objective of the study is to compare the effectiveness and safety of low-dose rivaroxaban to those of warfarin among Asians with NVAF.
Source: International Journal of Cardiology - March 14, 2018 Category: Cardiology Authors: Hsin-Fu Lee, Yi-Hsin Chan, Hui-Tzu Tu, Chi-Tai Kuo, Yung-Hsin Yeh, Shang-Hung Chang, Lung-Sheng Wu, Lai-Chu See Source Type: research
Impact of BMI on clinical outcomes of NOAC therapy in daily care - Results of the prospective Dresden NOAC Registry (NCT01588119)
Direct acting non-Vitamin K antagonist oral anticoagulants (NOAC) are characterized by a fixed dosing regimen. Despite the potential for relative underdosing due to large distribution volumes, dose adjustments for patients with high body mass index (BMI) are not recommended. Since efficacy and safety data in obese patients are scarce, we evaluated the impact of BMI on clinical outcomes in daily care patients treated with NOAC for stroke prevention in atrial fibrillation or venous thromboembolism.
Source: International Journal of Cardiology - March 14, 2018 Category: Cardiology Authors: L. Tittl, S. Endig, S. Marten, A. Reitter, I. Beyer-Westendorf, J. Beyer-Westendorf Source Type: research
