Filtered By:
Source: International Journal of Cardiology
Condition: Atrial Fibrillation
This page shows you your search results in order of date. This is page number 2.
Order by Relevance | Date
Total 388 results found since Jan 2013.
Persisting stroke risk in patients with atrial fibrillation despite proper anticoagulation – Unmet clinical needs
Oral anticoagulation (OAC) is crucial to prevent cardioembolic stroke in patients with atrial fibrillation (AF). Development of the direct oral anticoagulants (DOAC), which inhibit activities of the coagulant proteases thrombin and activated factor X (FXs), has improved the safety and efficacy of anticoagulation in AF, compared to traditional vitamin K antagonists like warfarin [1,2]. Yet in a small, but numerically relevant proportion of up to 2% of patients, this cornerstone principle fails for unclear reasons.
Source: International Journal of Cardiology - August 6, 2022 Category: Cardiology Authors: Florian Bruns, Dobromir Dobrev, Anke C. Fender Tags: Editorial Source Type: research
Clinical outcomes of left atrial appendage occlusion versus direct oral anticoagulation in patients with atrial fibrillation and prior ischemic stroke: A propensity-score matched study
This propensity-score matched study investigated clinical outcomes associated with left atrial appendage occlusion (LAAO) versus direct oral anticoagulation (DOAC) in patients with AF and prior ischemic stroke.
Source: International Journal of Cardiology - June 30, 2022 Category: Cardiology Authors: Kasper Korsholm, Jan B. Valentin, Dorte Damgaard, Hans-Christoph Diener, Alan John Camm, Ulf Landmesser, David Hildick-Smith, S øren Paaske Johnsen, Jens Erik Nielsen-Kudsk Source Type: research
Assessment of atrial function by echocardiography: Can this be used to assess the arrhythmogenic atrial substrate?
Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia. It is associated with a high risk for thromboembolic stroke, heart failure, decreased quality of life and cognitive impairment, all increasing mortality. After confirmation of AF, comprehensive assessment of i) stroke risk, ii) symptom severity, iii) severity of AF-burden and iv) atrial substrate severity is recommended in accordance with the 4S-AF scheme proposed by the current European AF-guidelines to provide optimal treatment for the individual patient [1].
Source: International Journal of Cardiology - June 1, 2022 Category: Cardiology Authors: Florian Bruns, Dobromir Dobrev Tags: Editorial Source Type: research
The great discovery of DOACs and why physicians insist on misusing it: A paradox of the 21 century
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and has been one of the most studied disease in the world for the last 20 years. As it is a frequent cause of preventable strokes, substantial research efforts were directed toward gaining detailed information about effective prophylactic treatments. New evidence has been continuously published and resulted in the approval of direct-acting oral anticoagulants (DOACs) i n this scenario, which are safer and easier to use than vitamin K antagonists (VKA).[1]Although the randomized clinical trials that substantiated the approval of DOACs were based in ...
Source: International Journal of Cardiology - June 1, 2022 Category: Cardiology Authors: Fl ávia Bittar B. Arantes, Remo H.M. Furtado Tags: Editorial Source Type: research
Predictive value of left atrial strain in relation to atrial fibrillation following acute myocardial infarction
This study aimed to determine the prognostic value of left atrial (LA) strain, obtained by speckle tracking echocardiography (STE), in predicting incident AF outcomes following STEMI treated with primary percutaneous coronary intervention (pPCI).Methods and results:This prospective study comprised of 392 STEMI patients treated with pPCI.
Source: International Journal of Cardiology - May 13, 2022 Category: Cardiology Authors: Anne-Sophie Winther Svartstein, Mats H øjbjerg Lassen, Kristoffer Grundtvig Skaarup, Gabriela Lladó Grove, Frederikke Vyff, Kirstine Ravnkilde, Sune Pedersen, Søren Galatius, Daniel Modin, Tor Biering-Sørensen Source Type: research
Residual stroke risk after left atrial appendage closure in patients with prior Oral anticoagulation failure
We report outcomes of LAAC in patients with OAC failure compared to those with classic indications of OAC contraindications.
Source: International Journal of Cardiology - February 24, 2022 Category: Cardiology Authors: Rados ław Pracoń, Kamil Zieliński, Sripal Bangalore, Marek Konka, Mariusz Kruk, Cezary Kępka, Piotr Trochimiuk, Mariusz Dębski, Jakub Przyłuski, Edyta Kaczmarska, Zofia Dzielińska, Andrzej Kurowski, Adam Witkowski, Marcin Demkow Source Type: research
Percutaneous left atrial appendage closure vs oral anticoagulation: The scariest might be the cheepest
Left Atrial Appendage Closure (LAAC) in patients with atrial fibrillation (AF) and consequent elevated risk of thromboembolic events has an excellent safety profile, with an equal efficacy in preventing stroke, compared with vitamin K antagonists in patients without contraindications to oral anticoagulants [1]. It is also noninferior to direct oral anticoagulants (DOACs) in preventing major AF-related ischemic and haemorrhagic events [2]. Nevertheless, according to the current practice guidelines, percutaneous LAAC is still recommended only in patients with AF at increased risk of stroke and with contraindications to long-term OAC [3,4].
Source: International Journal of Cardiology - January 29, 2022 Category: Cardiology Authors: Patrizio Mazzone, Paolo Della Bella, Francesca Baratto Tags: Editorial Source Type: research
The risk and timing of acute ischemic stroke after electrical cardioversion for atrial fibrillation in Taiwan: A nationwide population-based cohort study
There is a positive association between electrical cardioversion (ECV) and acute ischemic stroke (AIS). Although 4 weeks of anticoagulation therapy after ECV in atrial fibrillation (AF) patients is generally suggested by current guidelines to reduce the risk of AIS, limited studies have been conducted in Asian populations to determine the risk and timing of AIS after ECV for AF in recent years. Therefore, we aim to use the National Health Insurance Research Database (NHIRD) in Taiwan to determine the risk and timing of AIS after ECV for AF.
Source: International Journal of Cardiology - December 23, 2021 Category: Cardiology Authors: Chih-Kang Huang, Jen-Chun Wang, Chi-Hsiang Chung, Sy-Jou Chen, Wen-I Liao, Wu-Chien Chien Source Type: research
Screening for atrial fibrillation: If I was left to my own devices
Atrial fibrillation (AF) is established as the most prevalent clinical arrhythmia, and a major risk factor for stroke, death, heart failure, cognitive decline, and hospitalisation [1]. Ranking these complications is difficult, however ischemic stroke caused by AF is posing a significant burden to patients, their next of kin, to physicians and to the health care system. The stroke risk in AF patients can be markedly lowered by oral anticoagulation (OAC) treatment [2], but many patients with AF have few or no symptoms [3], hence health care contacts and arrhythmia detection might be lacking [4].
Source: International Journal of Cardiology - November 16, 2021 Category: Cardiology Authors: Emma Svennberg, Johan Engdahl Tags: Editorial Source Type: research
Using machine learning to predict atrial fibrillation diagnosed after ischemic stroke
Selecting best candidates for prolonged poststroke cardiac monitoring in acute ischemic stroke (AIS) patients is still challenging. We aimed to develop a machine learning (ML) model to select AIS patients at high risk of poststroke atrial fibrillation (AF) for prolonged cardiac monitoring and then to compare ML model with traditional risk scores and classic statistical logistic regression (classic-LR) model.
Source: International Journal of Cardiology - November 11, 2021 Category: Cardiology Authors: Xiaohan Zheng, Fusang Wang, Juan Zhang, Xiaoli Cui, Fuping Jiang, Nihong Chen, Junshan Zhou, Jinsong Chen, Song Lin, Jianjun Zou Source Type: research
Screening for atrial fibrillation in the elderly
Any screening program in the community, while providing useful and previously unknown information, has the potential of uncovering findings of uncertain interpretation, especially regarding their impact on clinical outcomes, and therefore the justification of extending the screening to larger cohorts with substantial health care costs. As Shang and colleagues [1] remind us, the STROKESTOP study [2] detected a modest benefit from screening for atrial fibrillation (AF) on the primary combined endpoint of ischaemic or haemorrhagic stroke, systemic embolism, bleeding leading to hospitalisation and all-cause death (1.1% absolut...
Source: International Journal of Cardiology - November 2, 2021 Category: Cardiology Authors: Carlo Mannina, Marco R. Di Tullio Tags: Letter to the Editor Source Type: research
Proteomic profiles of patients with atrial fibrillation provide candidate biomarkers for diagnosis
Atrial fibrillation (AF) is the most common cardiac arrhythmia worldwide with an increasing risk of heart failure, stroke, and thromboembolic events. Currently distinct pathophysiological mechanisms during AF development and valuable biomarkers for AF management remain unknown.
Source: International Journal of Cardiology - September 27, 2021 Category: Cardiology Authors: WeiYi Zhong, Hui Yang, YuLin Wang, Ye Yang, ChangFa Guo, ChunSheng Wang, Qiang Ji Source Type: research
Antithrombotic therapy in the elderly: The more we know, the more we can offer
Atrial fibrillation (AF) and coronary artery disease commonly co-exist in elderly patients [1]. While long-term oral anticoagulation therapy is needed to prevent stroke and systemic embolism, antiplatelet agents are recommended to reduce the risk of coronary thrombotic events in this patient population [2]. Elderly patients are prone to both an increased risk of bleeding and of thrombotic events [3,4]. Therefore, keeping a favorable balance between ischemic and hemorrhagic risks in this growing population represents a major challenge in clinical practice.
Source: International Journal of Cardiology - July 6, 2021 Category: Cardiology Authors: Pedro A. Lemos, Patricia O. Guimar ães, Marcelo Franken, Otavio Berwanger Tags: Editorial Source Type: research
Frequency of cardiac arrhythmias in older adults: Findings from the Subclinical Atrial Fibrillation and Risk of Ischemic Stroke (SAFARIS) study
Prolonged monitoring of cardiac rhythm has been used to screen for subclinical atrial fibrillation (AF); little is known about other arrhythmias in the general population, especially in the elderly, who are at higher risk of arrhythmias.
Source: International Journal of Cardiology - May 6, 2021 Category: Cardiology Authors: Carlo Mannina, Zhezhen Jin, Kenji Matsumoto, Kazato Ito, Angelo Biviano, Mitchell S.V. Elkind, Tatjana Rundek, Shunichi Homma, Ralph L. Sacco, Marco R. Di Tullio Source Type: research
Detection of atrial fibrillation in asymptomatic at-risk individuals
The objective of this study is to determine the AF burden in an asymptomatic, at-risk population. We also sought to investigate potential predictors of undiagnosed AF.
Source: International Journal of Cardiology - April 28, 2021 Category: Cardiology Authors: Anatoly Langer, Jeff S. Healey, F. Russell Quinn, George Honos, Isabelle Nault, Mary Tan, Diane Camara, David M. Newman, Richard Godin, On Behalf of the AWARE AF Program Tags: Short communication Source Type: research
