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Source: International Journal of Cardiology
Condition: Atrial Fibrillation
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Total 388 results found since Jan 2013.
Hyperuricemia is independently associated with increased risk of atrial fibrillation: A meta-analysis of cohort studies
Atrial fibrillation (AF) is a common cardiovascular disease in the elderly and the most common cardiac arrhythmia [1]. AF increases risk of mortality morbidity, and is associated with risks of a series of subsequent diseases, such as cardiovascular disease, stroke, and impaired cognition [1–3]. A better understanding of AF risk factors is essential for the development of preventive strategies and treatment of AF. Though several studies were published to assess the association between hyperuricemia and AF risk, no consistent results were reported [4–10].
Source: International Journal of Cardiology - February 24, 2015 Category: Cardiology Authors: Xiang Xu, Na Du, Robin Wang, Yangang Wang, Shanglang Cai Tags: Letter to the editor Source Type: research
Female gender and atrial fibrillation: An association with worse prognosis and outcomes
Females with atrial fibrillation (AF) are at increased risk for ischemic stroke but have been under-represented in AF cohorts. Without anticoagulation, women are at higher risk than men for AF-related thromboembolic events (TE) but results are not consistent [1,2]. Interestingly, vascular complication rates after AF ablation had been recently shown to be also higher in females [3]. Female sex has been included in the CHA2DS2-VASc score for assessing thromboembolic risk, which doubles in women between the ages of 55 and 65, the menopausal period, when estradiol levels decrease by about 60% [4].
Source: International Journal of Cardiology - February 24, 2015 Category: Cardiology Authors: Jelena Kornej, Andreas Bollmann, Gerhard Hindricks, Gregory Y.H. Lip Tags: Letter to the Editor Source Type: research
Primary prophylactic anticoagulation is mandatory if noncompaction is associated with atrial fibrillation or heart failure
Whether patients with left ventricular hypertrabeculation / noncompaction (LVHT) require primary prophylaxis with oral anticoagulation (OAC) to prevent stroke / embolism is unsolved [1]. However, if LVHT is associated with atrial fibrillation (AFIB) / atrial flutter (AFLU), or systolic dysfunction or both, OAC for primary prophylaxis of embolism is mandatory, as illustrated by the following case.
Source: International Journal of Cardiology - February 23, 2015 Category: Cardiology Authors: Josef Finsterer, Claudia Stöllberger Tags: Letter to the editor Source Type: research
Vitamin D deficiency and atrial fibrillation
Vitamin D deficiency has been linked with hypertension, coronary artery disease, and stroke, but there is no consensus regarding the possible association between vitamin D deficiency and atrial fibrillation (AF). Vitamin D negatively regulates the renin–angiotensin–aldosterone-system (RAAS), mediates calcium homeostasis, binds to vitamin D receptors on cardiac myocytes, and has antioxidant properties that may reduce levels of reactive oxygen species (ROS) in the atria, which contribute to inflammation and proarrhythmic substrate formation.
Source: International Journal of Cardiology - February 10, 2015 Category: Cardiology Authors: Joseph Thompson, Rynda Nitiahpapand, Prashan Bhatti, Antonios Kourliouros Tags: Review Source Type: research
Letter by Bassareo regarding the article of Larrson et al. “Incidence of atrial fibrillation in relation to birth weight and preterm birth”
we have read with great interest the commendable article by Larsson and Colleagues, who have demonstrated the association of low birth weight (in men) and high birth weight with an increased risk of the onset of atrial fibrillation. It implies an increased risk of developing an embolic stroke in these subjects as well [1].
Source: International Journal of Cardiology - December 30, 2014 Category: Cardiology Authors: P.P. Bassareo, V. Fanos, G. Mercuro Tags: Letters to the Editor Source Type: research
Thrombosis in Fontan patient on apixaban
We report a case of large thrombus in a 24-year-old male born with double inlet left ventricle in the lateral tunnel Fontan while on apixaban.
Source: International Journal of Cardiology - December 27, 2014 Category: Cardiology Authors: Candida Pinto, Bennett P. Samuel, Christopher Ratnasamy, Joseph J. Vettukattil Source Type: research
Antiplatelet Properties of Oral Anticoagulants
Until recently, vitamin K antagonists (VKA) were the only oral anticoagulant drugs used in clinical practice for stroke or systemic embolism prevention in patients with non-valvular atrial fibrillation (AF). New oral anticoagulant drugs such as dabigatran etexilate and rivaroxaban have been developed and are currently available as an alternative in this indication. Both drugs were demonstrated to be non-inferior to warfarin for the prevention of stroke or systemic embolism in patients with non-valvular AF in the RE-LY and ROCKET trials [1,2].
Source: International Journal of Cardiology - December 23, 2014 Category: Cardiology Authors: Corinne Frère, Marc Laine, Franck Paganelli, Françoise Dignat-George, Laurent Bonello Tags: Letter to the Editor Source Type: research
Obstructive sleep apnea and the risk of ischemic stroke in patients with atrial fibrillation
Atrial fibrillation (AF) is associated with significant morbidity and mortality. Prevention of thromboembolism with oral anticoagulant agents is an important treatment for patients with AF. CHADS2 and CHA2DS2-VASc score has been widely used as the initial approach to assess future stroke risk among AF patients. Obstructive sleep apnea (OSA) is a common breathing disorder associated with substantial cardiovascular morbidity and mortality. It has been reported as an independent risk factor for ischemic stroke [1–4].
Source: International Journal of Cardiology - December 2, 2014 Category: Cardiology Authors: Chun-Chin Chang, Chun-Chih Chiu, Chia-Hung Chiang, Chin-Chou Huang, Wan-Leong Chan, Po-Hsun Huang, Yu-Chun Chen, Tzeng-Ji Chen, Chia-Min Chung, Shing-Jong Lin, Jaw-Wen Chen, Hsin-Bang Leu Tags: Letter to the Editor Source Type: research
Screening for atrial fibrillation in general practice: A national, cross-sectional study of an innovative technology
To test the use of three lead monitoring as a screening tool for atrial fibrillation (AF) in general practice. AF is responsible for up to a quarter of all strokes and is often asymptomatic until a stroke occurs.
Source: International Journal of Cardiology - November 29, 2014 Category: Cardiology Authors: Gerard Bury, Davina Swan, Walter Cullen, David Keane, Helen Tobin, Mairead Egan, David Fitzmaurice, Crea Carberry, Cecily Kelleher Source Type: research
Are direct oral anticoagulants effective in reducing systemic embolism in patients with atrial fibrillation? A systematic review and meta-analysis of the literature
Atrial fibrillation (AF) is the most prevalent sustained heart arrhythmia. It is the most important clinical risk factor for systemic embolism (SE) and is regarded to be the cause of stroke in up to one fourth of cases [1]. However, since stroke is much more prevalent than SE in patients with AF, the latter is not considered to be a main single outcome parameter in AF trials. As a consequence, the majority of trials on the role of anticoagulants in AF patients have focused over stroke prevention, and SE has been included only as a part of composite end-points.
Source: International Journal of Cardiology - November 26, 2014 Category: Cardiology Authors: Nicola Mumoli, Marco Cei, Josè Vitale, Andrea Fontanella, Francesco Dentali Tags: Letters to the Editor Source Type: research
Non-vitamin K antagonist oral anticoagulants (NOACs) for stroke prevention in Asian patients with atrial fibrillation: Time for a reappraisal
Non-vitamin K antagonist oral anticoagulants (NOACs) have changed the landscape for stroke prevention in atrial fibrillation (AF). Given the huge burden of AF in Asians, more attention to stroke prevention is clearly needed. Aiming to provide an overview and reappraisal of stroke prevention in Asians with AF, we searched MEDLINE for information on NOACs in Asians. In addition, abstracts from national and international cardiovascular meetings were studied to identify unpublished studies.In the 4 recent Phase 3 trials comparing NOACs to warfarin, a consistent pattern is evident.
Source: International Journal of Cardiology - November 26, 2014 Category: Cardiology Authors: Gregory Y.H. Lip, Kang-Ling Wang, Chern-En Chiang Tags: Review Source Type: research
Non-Vitamin K Oral Anticoagulants (NOACs) for stroke prevention in Asian patients with atrial fibrillation: Time for a reappraisal
Non-Vitamin K Antagonist Oral Anticoagulants (NOACs) have changed the landscape for stroke prevention in atrial fibrillation (AF). Given the huge burden of AF in Asians, more attention to stroke prevention is clearly needed. Aiming to provide an overview and reappraisal of stroke prevention in Asians with AF, we searched MEDLINE for information on NOACs in Asians. In addition, abstracts from national and international cardiovascular meetings were studied to identify unpublished studies.In the 4 recent Phase 3 trials comparing NOACs to warfarin, a consistent pattern is evident.
Source: International Journal of Cardiology - November 26, 2014 Category: Cardiology Authors: Gregory Y.H. Lip, Kang-Ling Wang, Chern-En Chiang Tags: Review Source Type: research
Red blood cell distribution width and left atrial thrombus or spontaneous echo contrast in patients with non-valvular atrial fibrillation
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with an increased risk of cardio-embolic stroke and mortality. AF patients are under an increased risk of thromboembolism and stroke primarily from the development of thrombi within the left atrium. Pathological changes in blood constituents like slow blood flow, stasis, form a vortex, promote atrial endothelial damage and left atrial thrombus (LAT) formation [1]. Transesophageal echocardiography (TEE) can help us to identify LAT and left atrial spontaneous echo contrast (LASEC) which has been demonstrated as a precursor of LAT [2].
Source: International Journal of Cardiology - November 25, 2014 Category: Cardiology Authors: Jianping Zhao, Tong Liu, Panagiotis Korantzopoulos, Huaying Fu, Qingmiao Shao, Ya Suo, Chenghuan Zheng, Gang Xu, Enzhao Liu, Yanmin Xu, Changyu Zhou, Guangping Li Tags: Letter to the editor Source Type: research
Antithrombotic therapy for atrial fibrillation in patients with acute ischemic stroke or transient ischemic attack
Although warfarin is more effective than are antiplatelet drugs for preventing stroke in patients with atrial fibrillation (AF), it is usually underutilized after stroke for various reasons. A global AF registry study indicated that warfarin was prescribed even less frequently for stroke prevention in Asia than in the West [1]. The major problem of using warfarin in Asian populations is the increased risk of intracranial bleeding. The purpose of this study was to evaluate the use of antithrombotic therapy at discharge in a consecutive cohort of patients with acute ischemic stroke or transient ischemic attack (TIA) and AF.
Source: International Journal of Cardiology - November 13, 2014 Category: Cardiology Authors: Poh-Shiow Yeh, Chun-Ming Yang, Sheng-Hsiang Lin, Wei-Ming Wang, Po-Sheng Chen, Huey-Juan Lin, Kao-Chang Lin, Chia-Yu Chang, Tain-Junn Cheng, Yi-Heng Li Tags: Letter to the editor Source Type: research
NT-proBNP in “low risk” patients with atrial fibrillation
Atrial fibrillation (AF) increases the risk of stroke and death and constitutes a significant societal health and economic problem [1,2]. Prediction of thromboembolic risk is most commonly made using a clinical score such as the CHADS2 or CHA2DS2–VASc [3]. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is associated with mortality and cardiovascular events in patients with AF and has been shown to improve risk stratification beyond the CHA2DS2-VASc score [4]. However, the association between NT-proBNP levels and the CHA2DS2-VASc score as well as the prevalence of high NT-proBNP levels indicating high risk in othe...
Source: International Journal of Cardiology - November 7, 2014 Category: Cardiology Authors: Jelena Kornej, Susanne Löbe, Elena Efimova, Daniela Husser, Gerhard Hindricks, Andreas Bollmann Tags: Letter to the editor Source Type: research
