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Source: International Journal of Cardiology
Condition: Atrial Fibrillation
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Total 388 results found since Jan 2013.
Uninterrupted NOAC therapy in patients undergoing catheter ablation of atrial fibrillation: “Dual anticoagulant therapy” ready for primetime or systematic overtreatment?
Catheter ablation of atrial fibrillation (AF) appears as a very promising technique to reduce arrhythmia episodes in patients with AF [1]. The major adverse events of such procedures are bleeding complications and stroke. Therefore, several studies were performed to assess efficacy and safety of different oral anticoagulants like warfarin (VKA) and non-VKA oral anticoagulants (NOAC). NOAC therapy has been explored in patients with chronic AF and in patients undergoing antiarrhythmic procedures [2, 3].
Source: International Journal of Cardiology - June 13, 2018 Category: Cardiology Authors: Andreas Goette Tags: Editorial Source Type: research
Bayes syndrome: Improving risk stratification in chronic heart failure?
The progressive ageing of population is leading to a significant increase of the incidence of heart failure (HF), one of the epidemics of the 21th Century. In addition, atrial fibrillation (AF) is the most common arrhythmia in elderly patients, and is associated with a higher incidence of stroke and mortality. A significant association between HF and AF has been consistently described, and its combination increases morbidity and mortality.
Source: International Journal of Cardiology - June 13, 2018 Category: Cardiology Authors: Albert Ariza-Sol é, Carme Guerrero, Francesc Formiga Tags: Editorial Source Type: research
Improved survival and reduced stroke risk in patients with atrial fibrillation: Is catheter ablation winning the rhythm-control race?
Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with increased thromboembolic risk and mortality [1]. Catheter ablation as a strategy in managing this complex arrhythmia is generally reserved for symptomatic patients who are intolerant or refractory to anti-arrhythmic drugs for symptom control [2]. Indeed, catheter ablation has been repeatedly shown to be effective in improving symptom control and quality of life although the lack of “hard” endpoints to date is well recognized.
Source: International Journal of Cardiology - June 8, 2018 Category: Cardiology Authors: Kadhim Kadhim, Dennis H. Lau, Dominik Linz, Prashanthan Sanders Tags: Editorial Source Type: research
Association of catheter ablation for atrial fibrillation with mortality and stroke: A systematic review and meta-analysis
Maintenance of sinus rhythm has been associated with lower mortality, but whether atrial fibrillation (AF) ablation per se benefits hard outcomes such as mortality and stroke is still debated.
Source: International Journal of Cardiology - June 8, 2018 Category: Cardiology Authors: S érgio Barra, Jakub Baran, Kumar Narayanan, Serge Boveda, Simon Fynn, Patrick Heck, Andrew Grace, Sharad Agarwal, João Primo, Eloi Marijon, Rui Providência Source Type: research
Vagal impact of cryoballoon ablation during pulmonary vein isolation
Atrial fibrillation (AF) is the most common cardiac arrhythmia, resulting in hemodynamic abnormalities and thromboembolic events. The prevalence of AF is around 1% in the general population, increasing with age. It results in a 5-fold increased risk of ischemic stroke, 3-fold increased risk of heart failure, and 2-fold increased risk of both dementia and mortality. Hassaiguerre et al. [1] and Chen et al. [2] firstly reported the dominant and pathologic role of pulmonary vein (PV) triggers as being responsible for the arrhythmogenesis of AF.
Source: International Journal of Cardiology - June 7, 2018 Category: Cardiology Authors: Ting-Yung Chang, Chin-Yu Lin, Shih-Ann Chen Tags: Editorials Source Type: research
The safety and efficacy of non-vitamin K antagonist oral anticoagulants in atrial fibrillation in the elderly
Atrial fibrillation (AF) is the most common arrhythmia and its prevalence increases with age. Age also increases the risk of thromboembolism related to AF. As a result, elderly patients are at increased risk of AF-related stroke compared to younger patients. Age, however, also increases the risk of bleeding, including that of intracranial haemorrhage, an important cause of death and disability. Elderly patients with AF are, therefore, often undertreated due to the fear of bleeding complications, although recent data suggest an even greater net clinical benefit for anticoagulation in general in the elderly, even the very el...
Source: International Journal of Cardiology - June 7, 2018 Category: Cardiology Authors: Giuseppe Patti, Ilaria Cavallari, Olivier Hanon, Raffaele De Caterina Source Type: research
Prevalence of atrial fibrillation in different socioeconomic regions of China and its association with stroke: Results from a national stroke screening survey
This study aimed to estimate the prevalence of AF in different socioeconomic regions of China and identify its association with stroke, through a national survey.
Source: International Journal of Cardiology - June 1, 2018 Category: Cardiology Authors: Xiaojun Wang, Qian Fu, Fujian Song, Wenzhen Li, Xiaoxv Yin, Wei Yue, Feng Yan, Hong Zhang, Hao Zhang, Zhenjie Teng, Longde Wang, Yanhong Gong, Zhihong Wang, Zuxun Lu Source Type: research
Biomarkers (plasma trimethylamine-N-oxide) to predict atrial fibrillation: Are we there yet?
Atrial fibrillation (AF) is the most prevalent arrhythmia and is projected to rise from 2.7 –6.1 million in 2010 to 12.1 million by 2030 [1]. AF portends a 4–5 fold risk of ischemic stroke in non-anticoagulated patients, and is an independent risk factor for ischemic stroke severity, recurrence, and mortality [1]. Due to the alarming increase in global prevalence with the attached incr ease in morbidity, mortality, and cost there has been increased effort to identify risk factors in the hope that prevention would turn the tide of this disease [1,2].
Source: International Journal of Cardiology - May 30, 2018 Category: Cardiology Authors: Mihail G. Chelu, Na Li Tags: Editorial Source Type: research
Low population prevalence of atrial fibrillation in rural Uganda: A community-based cross-sectional study
Atrial fibrillation (AF) is a major risk factor for stroke, which is the leading cause of cardiovascular mortality in sub-Saharan Africa. However, there is limited population-based epidemiological data on AF in sub-Saharan Africa. We sought to estimate the prevalence and correlates of AF in rural Uganda.
Source: International Journal of Cardiology - May 24, 2018 Category: Cardiology Authors: Rahul G. Muthalaly, Bruce A. Koplan, Alfred Albano, Crystal North, Jeffrey I. Campbell, Bernard Kakuhikire, Dagmar Vo řechovská, John D. Kraemer, Alexander C. Tsai, Mark J. Siedner Source Type: research
Heart failure and the development of atrial fibrillation in Hispanics, African Americans and non-Hispanic Whites
Atrial fibrillation (AF) is the most common cardiac arrhythmia [1], whose prevalence is increasing [1,2]. It represents a major public health problem and is closely related to stroke, mortality, decreased quality of life and a high health-care cost burden [3]. Heart failure (HF) is a growing epidemic and likely to impact 9 million US adults by 2030 [16]. AF and HF are closely linked [5], sharing similar risk factors with neurohormonal, cellular, extracellular and electrophysiologic changes of one predisposing the other [6 –8].
Source: International Journal of Cardiology - May 22, 2018 Category: Cardiology Authors: Eric Shulman, Tina Shah, Alon Y. Mazori, Jay J. Chudow, Faraj Kargoli, Dmitriy Nevelev, Jorge Romero, Luigi Di Biase, John Fisher, Jay Gross, Kevin J. Ferrick, Andrew Krumerman Source Type: research
The not-so-sweet problem of hearts aflutter: Dissecting stroke risk in atrial fibrillation with concomitant diabetes
Stroke is an important clinical condition associated with increased morbidity and mortality. Despite availability of effective oral anticoagulants (OAC), stroke prevention remains inadequate, particularly in patients with diabetes mellitus [1]. The study by XXXX and colleagues [2] in this issue of the International Journal of Cardiology examined for the first time if diabetes type 1 (T1D) or type 2 (T2D) impact differently on stroke risk specifically in patients with atrial fibrillation (AF). The investigators further explored if timing of OAC initiation once AF is diagnosed differs between T1D and T2D patients.
Source: International Journal of Cardiology - May 19, 2018 Category: Cardiology Authors: Anke C. Fender, Dobromir Dobrev Tags: Editorial Source Type: research
Advanced interatrial block predicts new-onset atrial fibrillation and ischemic stroke in patients with heart failure: The “Bayes' Syndrome-HF” study
We examined the prevalence of IAB and whether advanced IAB could predict new-ons et AF and/or stroke in HF patients.
Source: International Journal of Cardiology - May 18, 2018 Category: Cardiology Authors: Luis Alberto Escobar-Robledo, Antoni Bay és-de-Luna, Josep Lupón, Adrian Baranchuk, Pedro Moliner, Manuel Martínez-Sellés, Elisabet Zamora, Marta de Antonio, Mar Domingo, Germán Cediel, Julio Núñez, Evelyn Santiago-Vacas, Antoni Bayés-Genís Source Type: research
Oral anticoagulation alone for concomitant stable coronary artery disease and atrial fibrillation: A definitive strategy?
Thrombus formation, albeit with partially different mechanisms, is the common denominator of adverse ischemic events in both coronary artery disease (CAD) and atrial fibrillation (AF) [1]. Accordingly, long-term oral antiplatelet therapy with aspirin, and oral anticoagulation (OAC) with either warfarin or a direct oral anticoagulant (DOAC), including dabigatran, rivaroxaban, apixaban, and edoxaban, have long been established as the standard treatments for the prevention of (recurrent) cardiac ischemic events and stroke, respectively [2].
Source: International Journal of Cardiology - May 16, 2018 Category: Cardiology Authors: Andrea Rubboli Source Type: research
Interventional left atrial appendage closure may affect metabolism of essential amino acids and bioenergetic efficacy
This study evaluates the impact of LAAC on the metabolism of essential amino acids, creatinine and kynurenine.
Source: International Journal of Cardiology - May 15, 2018 Category: Cardiology Authors: J. Rusnak, M. Behnes, A. Saleh, C. Fastner, K. Sattler, C. Barth, A. Wenke, B. Sartorius, K. Mashayekhi, U. Hoffmann, G. Yuecel, S. Lang, M. Borggrefe, I. Akin Source Type: research
Percutaneous left atrial appendage closure with complex anatomy by using the staged ‘kissing-Watchman’ technology with double devices
Left atrial appendage closure (LAAC) is an efficient alternative of oral anticoagulation to prevent stroke in patients with non-valvular atrial fibrillation (NVAF). Due to complexities of LAA anatomy, a complete closure may not always be obtained with a single device. The aim of this study was to evaluate the feasibility and safety of the staged ‘kissing-Watchman’ technology to occlude the LAA with complex anatomy.
Source: International Journal of Cardiology - May 4, 2018 Category: Cardiology Authors: Lisheng Jiang, Erich Duenninger, Manuela Muenzel, Xin Xue, Adam Fazakas, Thorsten Keil, Jiangtao Yu Tags: Short communication Source Type: research
