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Source: International Journal of Cardiology
Condition: Atrial Fibrillation

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Total 388 results found since Jan 2013.

Yield of atrial fibrillation detection with Textile Wearable Holter from the acute phase of stroke: Pilot study of Crypto-AF registry
We describe the feasibility of monitoring with a Textile Wearable Holter (TWH) in patients included in Crypto AF registry.
Source: International Journal of Cardiology - October 22, 2017 Category: Cardiology Authors: Jorge Pagola, Jesus Juega, Jaume Francisco-Pascual, Angel Moya, Mireia Sanchis, Alejandro Bustamante, Anna Penalba, Maria Usero, Elisa Cortijo, Juan F. Arenillas, Ana I. Calleja, Maria Sandin-Fuentes, Jeronimo Rubio, Fernando Mancha, Irene Escudero-Martin Source Type: research

Clinical conundrums in antithrombotic therapy management: A Delphi Consensus panel
Anticoagulants are recommended for the prevention of stroke/systemic embolism for most patients with atrial fibrillation (AF) and for the treatment of patients with venous thromboembolism (VTE). Regulatory-driven randomized trials, however, typically exclude extreme patient scenarios involving, for instance, severe bleeding, ischaemic risk, frailty or renal impairment, despite their common occurrence in clinical practice. Uncertainty in the management of such cases leads to a high degree of variability in therapeutic approaches.
Source: International Journal of Cardiology - September 18, 2017 Category: Cardiology Authors: Paolo Colonna, Felicita Andreotti, Walter Ageno, Vittorio Pengo, Niccol ò Marchionni Source Type: research

Left Atrial Appendage Closure for Prevention of Death, Stroke, and Bleeding in Patients with Nonvalvular Atrial Fibrillation
Nonvalvular atrial fibrillation (AF) is the most frequent arrhythmia with a prevalence of 1% - 2% in the general population. Its prevalence increases with age and its diagnosis benefits of improvement and simplification of technologies for its detection. Today, AF affects approximately 7% of individuals age>65years and 15% –20% of octogenarians. Due to stasis and activation of coagulation in a fibrillating atrium, patients are at increased risk of thromboembolism, in particular ischemic stroke, with an overall stroke risk of 5% per year.
Source: International Journal of Cardiology - August 26, 2017 Category: Cardiology Authors: Steffen Gloekler, Jacqueline Saw, Konstantinos C. Koskinas, Werner Jung, Fabian Nietlispach, Bernhard Meier Source Type: research

Excessive atrial ectopic activity as an independent risk factor for ischemic stroke
Excessive atrial ectopic activity (EAEA) has been related with an increased risk of atrial fibrillation (AF) and stroke but different cutoff values have been used. We aimed to determine the association between EAEA and stroke, AF and overall death.
Source: International Journal of Cardiology - August 26, 2017 Category: Cardiology Authors: Rita Marinheiro, Leonor Parreira, Pedro Amador, Catarina S á, Tatiana Duarte, Rui Caria Source Type: research

Use of statins and adverse outcomes in patients with atrial fibrillation: An analysis from the EURObservational Research Programme Atrial Fibrillation (EORP-AF) general registry pilot phase
Despite oral anticoagulation being highly effective in reducing stroke and thromboembolism, patients with atrial fibrillation (AF) still have a significant residual excess in mortality risk. Additional management strategies are needed to reduce the mortality risk seen in AF patients.
Source: International Journal of Cardiology - August 25, 2017 Category: Cardiology Authors: Marco Proietti, C écile Laroche, Ole Nyvad, Maciej Haberka, Vassilios P. Vassilikos, Aldo P. Maggioni, Giuseppe Boriani, Gregory Y.H. Lip, EORP-AF Pilot Investigators Source Type: research

Targeting supraventricular ectopic complexes: Which approach should be used and how does it affect atrial fibrillation?
Atrial fibrillation (AF) represents a major global health burden due to its high prevalence and significant impact on morbidity and mortality [1]. In addition to anticoagulation to reduce the risk of stroke, AF management includes normalization of the ventricular response ( ‘rate control’) or restoration and maintenance of normal sinus rhythm (‘rhythm control’). Although several large clinical trials have shown that both rate- and rhythm-control strategies produce similar outcomes, rhythm control is often attempted in symptomatic patients [1].
Source: International Journal of Cardiology - August 5, 2017 Category: Cardiology Authors: Jordi Heijman, Dobromir Dobrev, Harry J.G.M. Crijns Tags: Editorial Source Type: research

Dynamic balance of platelet reactivity in atrial fibrillation PARtially unravelled
The World Heart Federation recently launched a roadmap to reduce the substantial disease and healthcare burden associated with non-valvular atrial fibrillation (AF). AF is the most common and clinically significant form of cardiac arrhythmia, and independently associated with a 5-fold increased risk of ischemic stroke [1]. Thromboembolisms generally arise from structurally and electrically remodelled left atria exhibiting impaired contractility and blood stasis. Increased thrombogenicity may additionally predispose to both AF and stroke.
Source: International Journal of Cardiology - July 23, 2017 Category: Cardiology Authors: Anke C. Fender, Dobromir Dobrev Tags: Editorial Source Type: research

Clinical profile and outcomes in octogenarians with atrial fibrillation: A community-based study in a specific European health care area
Age increases risk of stroke and bleeding. Clinical trial data have had relatively low proportions of elderly subjects. We sought to study a Spanish population of octogenarians with atrial fibrillation (AF) by combining different sources of electronic clinical records from an area where all medical centres utilized electronic health record systems.
Source: International Journal of Cardiology - July 23, 2017 Category: Cardiology Authors: Mois és Rodríguez-Mañero, Estrella López-Pardo, Alberto Cordero, Omar Kredieh, María Pereira-Vazquez, Jose-Luis Martínez-Sande, Alvaro Martínez-Gomez, Carlos Peña-Gil, José Novo-Platas, Javier García-Seara, Pilar Mazón, Ricardo Laje, Isabel Mos Source Type: research

Risk of stroke in congestive heart failure with and without atrial fibrillation
This study estimated the risk of stroke and thromboembolism for patients with congestive heart failure (CHF) in the context of the general population, especially compared to those with atrial fibrillation (AF).
Source: International Journal of Cardiology - July 20, 2017 Category: Cardiology Authors: Si-Hyuck Kang, Joonghee Kim, Jin Joo Park, Il-Young Oh, Chang-Hwan Yoon, Hee-Jun Kim, Kyuseok Kim, Dong-Ju Choi Source Type: research

Left atrial appendage closure using AMPLATZER ™ devices: A large, multicenter, Italian registry
Left atrial appendage occlusion (LAAO) has been proven to be effective for stroke prophylaxis in patients with non-valvular atrial fibrillation (NVAF). We aim to assess the safety and efficacy of LAAO by AMPLATZER ™ devices in a large, multicenter, single-nation cohort of NVAF patients at high-risk of stroke and bleeding.
Source: International Journal of Cardiology - July 16, 2017 Category: Cardiology Authors: Sergio Berti, Gennaro Santoro, Elvis Brscic, Matteo Montorfano, Luigi Vignali, Paolo Danna, Claudio Tondo, Gianpiero D'Amico, Amerigo Stabile, Salvatore Sacc à, Giuseppe Patti, Antonio Rapacciuolo, Arnaldo Poli, Paolo Golino, Paolo Magnavacchi, Alberto D Source Type: research

Long-term stroke and bleeding risk in patients with atrial fibrillation treated with oral anticoagulants in contemporary practice: Providing evidence for shared decision-making
Oral anticoagulation is recommended as a lifelong therapy for most patients with atrial fibrillation (AF). However, data on long-term outcomes in clinical practice on these drugs are scarce, particularly for the recently approved agents. We aimed to describe differences in characteristics between patients in everyday practice and those enrolled in the pivotal trials, and to report long-term outcomes on oral anticoagulation in practice.
Source: International Journal of Cardiology - July 13, 2017 Category: Cardiology Authors: Peter A. Noseworthy, Xiaoxi Yao, Bernard J. Gersh, Ian Hargraves, Nilay D. Shah, Victor M. Montori Tags: Short communication Source Type: research

Pre-admission CHA2DS2-VASc score and outcome of patients with acute cerebrovascular events
The CHA2DS2-VASc score has been recommended for the assessment of thromboembolic risk in patients with atrial fibrillation. Data regarding the association between the pre-admission CHA2DS2-VASc score and the outcome of patients with stroke and TIA are scarce. We aimed to assess the predictive value of pre-admission CHA2DS2-VASc score for early risk stratification of patients with acute cerebrovascular event.
Source: International Journal of Cardiology - June 15, 2017 Category: Cardiology Authors: Guy Topaz, David Pereg, Mony Shuvy, Stefan Mausbach, Itzhak Kimiagar, Gregory Telman, Yona Kitay-Cohen, Dina Vorobeichik, Nir Shlomo, David Tanne Source Type: research

Long-term Detection of Atrial Fibrillation with Insertable Cardiac Monitors in a Real-world Cryptogenic Stroke Population
The long-term incidence of atrial fibrillation (AF) in cryptogenic stroke (CS) patients has been explored in carefully controlled clinical trials but real-world data are limited. We investigated the two-year incidence of AF in real-world clinical practice among a large cohort of patients with an insertable cardiac monitor (ICM) placed for AF detection following CS.
Source: International Journal of Cardiology - June 10, 2017 Category: Cardiology Authors: Paul D. Ziegler, John D. Rogers, Scott W. Ferreira, Allan J. Nichols, Mark Richards, Jodi L. Koehler, Shantanu Sarkar Source Type: research

Non-vitamin K antagonist oral anticoagulants compared with warfarin at different levels of INR control in atrial fibrillation: A meta-analysis of randomized trials
The efficacy and safety of warfarin for stroke prevention in atrial fibrillation (AF) depend on the time in the therapeutic range (TTR) with an international normalised ratio (INR) of 2.0 –3.0. This meta-analysis focused the relative efficacy and safety of non-VKA oral anticoagulants (NOAC) compared with warfarin at different thresholds of centre's TTR (cTTR).
Source: International Journal of Cardiology - June 2, 2017 Category: Cardiology Authors: Jo ão Carmo, Jorge Ferreira, Francisco Costa, Pedro Carmo, Diogo Cavaco, Salomé Carvalho, Francisco Morgado, Pedro Adragão, Miguel Mendes Source Type: research

Telomere length: A newly marker for predicting atrial fibrillation?
We read with great interest a recent article published in your journal entitled “Telomere shortening and telomerase activity in ischaemic cardiomyopathy patients – Potential markers of ventricular arrhythmia”. This paper demonstrated that telomere length (TL) was associated with fatal ventricular arrhythmia without a causal relationship being reported [1]. Shortening in T L has been linked to an increase in the risks of cardioembolic stroke [2] and cardiovascular diseases [3]. Recently, the potential relationship between TL and with atrial fibrillation (AF) has been investigated with conflicting results.
Source: International Journal of Cardiology - May 29, 2017 Category: Cardiology Authors: Nixiao Zhang, Gary Tse, Xue Liang, Guangping Li, Tong Liu Tags: Letter to the Editor Source Type: research