• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Comparative Safety Analysis of Oral Antipsychotics for In-Hospital Adverse Clinical Events in Older Adults After Major Surgery : A Nationwide Cohort Study
CONCLUSION: These results suggest that atypical antipsychotics and haloperidol have similar rates of in-hospital adverse clinical events in older patients with postoperative delirium who receive an oral low-to-moderate dose antipsychotic drug.PRIMARY FUNDING SOURCE: National Institute on Aging.PMID:37665998 | DOI:10.7326/M22-3021
Source: Annals of Internal Medicine - September 4, 2023 Category: Internal Medicine Authors: Dae Hyun Kim Su Been Lee Chan Mi Park Raisa Levin Eran Metzger Brian T Bateman E Wesley Ely Pratik P Pandharipande Margaret A Pisani Richard N Jones Edward R Marcantonio Sharon K Inouye Source Type: research

Dosing antipsychotics in special populations of patients with schizophrenia: Severe psychotic agitation, first psychotic episode and elderly patients
Expert Opin Pharmacother. 2021 Aug 2. doi: 10.1080/14656566.2021.1958781. Online ahead of print.ABSTRACTIntroduction: Antipsychotic (AP) dosing is well established in nonelderly patients with acute exacerbations of schizophrenia, but not in special populations.Areas covered: This review describes the AP dosing procedures that have been used in clinical studies for acute psychotic agitation, a first episode of psychosis (FEP), and elderly patients. AP dosing data was extracted from the databases of drug regulatory authorities, and from clinical studies available in the medical literature.Expert opinion: In acute psychotic a...
Source: Expert Opinion on Pharmacotherapy - August 2, 2021 Category: Drugs & Pharmacology Authors: Fay çal Mouaffak Florian Ferreri Julie Bourgin-Duchesnay Emmanuelle Baloche Olivier Blin Pierre Vandel Ricardo P Garay Pierre Vidailhet Emmanuelle Corruble Pierre-Michel Llorca Source Type: research

Autism in the Son of a Woman with Mitochondrial Myopathy and Dysautonomia: A Case Report
Conclusion Given emerging evidence that mitochondrial dysfunction, particularly in the electron transport chain needed for cellular energy production, is an underlying pathophysiological mechanism for some varieties of ASD, clinicians should have a high index of suspicion for mitochondrial disease, especially when they encounter a patient with unusual neurological or constitutional symptoms. The prevalence of mitochondrial disease in ASD patients may be as high as five percent, which means that it is not the “zebra”[27] diagnosis that it might be in a non-ASD patient, where prevalence is about 0.01 percent.10 Reference...
Source: Innovations in Clinical Neuroscience - October 9, 2015 Category: Neuroscience Authors: ICN Online Editor Tags: Anxiety Disorders Asperger's syndrome Autism Behavioral and Cognitive Neurology Case Report Current Issue Intellectual Disability Neurologic Systems and Symptoms Pervasive Developmental Disorders ASD autism spectrum disorder dysauton Source Type: research