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Role of Platelet to Lymphocyte Ratio (PLR) and its Correlation with NIHSS (National Institute of Health Stroke Scale) for Prediction of Severity in Patients of Acute Ischemic Stroke
CONCLUSION: Platelet to lymphocyte ratio (PLR) is a simple, cost effective and easily obtainable novel inflammatory marker that may help in predicting the severity of disease and prognosis in terms of functional outcome as evidenced by its increased value in patients of acute ischemic stroke as well as its linear positive correlation with NIHSS score.PMID:34227777
Source: Journal of the Association of Physicians of India - July 6, 2021 Category: General Medicine Authors: Deepti Sharma Nikhil Gandhi Source Type: research

Sex differences in outcomes after spontaneous intracerebral hemorrhage among patients with low total cholesterol levels
CONCLUSIONS: Our study showed that there were no sex differences in clinical outcomes of patients with ICH and low TC levels, which suggests that the effect of low cholesterol as a risk factor for cerebral hemorrhage is the same on patients of different sexs. The possible mechanisms need larger, prospective, multicenter studies to further research.PMID:33992602 | DOI:10.1016/j.amjms.2021.05.007
Source: The American Journal of the Medical Sciences - May 16, 2021 Category: General Medicine Authors: Qian Liu Wenjuan Zhao Xuan Zou Yonghong Xing Guanen Zhou Xin Li Source Type: research

Disability-free survival after major cardiac surgery: a population-based retrospective cohort study
CMAJ Open. 2021 Apr 16;9(2):E384-E393. doi: 10.9778/cmajo.20200096. Print 2021 Apr-Jun.ABSTRACTBACKGROUND: Cardiovascular research has traditionally been dedicated to "tombstone" outcomes, with little attention dedicated to the patient's perspective. We evaluated disability-free survival as a patient-defined outcome after cardiac surgery.METHODS: We conducted a retrospective cohort study of patients aged 40 years and older who underwent coronary artery bypass grafting (CABG) or single or multiple valve (aortic, mitral, tricuspid) surgery in Ontario between Oct. 1, 2008, and Dec. 31, 2016. The primary outcome was disability...
Source: cmaj - April 17, 2021 Category: General Medicine Authors: Louise Y Sun Anan Bader Eddeen Thierry G Mesana Source Type: research

Alcohol consumption and risk of cardiovascular outcomes and bleeding in patients with established atrial fibrillation
CMAJ. 2021 Jan 25;193(4):E117-E123. doi: 10.1503/cmaj.200778.ABSTRACTBACKGROUND: Little is known about the association between alcohol consumption and risk of cardiovascular events in patients with established atrial fibrillation (AF). The main aim of the current study was to investigate the associations of regular alcohol intake with incident stroke or systemic embolism in patients with established AF.METHODS: To assess the association between alcohol consumption and cardiovascular events in patients with established AF, we combined data from 2 comparable prospective cohort studies that followed 3852 patients with AF for ...
Source: Canadian Medical Association Journal - March 5, 2021 Category: General Medicine Authors: Philipp Reddiess Stefanie Aeschbacher Pascal Meyre Michael Coslovsky Michael K ühne Nicolas Rodondi Oliver Baretella J ürg H Beer Richard Kobza Giorgio Moschovitis Marcello Di Valentino Cyrill M üller Fabienne Steiner Leo H Bonati Christian Sticherling Source Type: research

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