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Gastrointestinal Bleeding in Acute Ischemic Stroke: Recent Trend and Predictors. (P6.040)
CONCLUSIONS:GIB is relatively known complication in setting of AIS. Decremental trend in recent years does not have any association with chemical or mechanical thrombolysis but instead was predicted by chronic altered metabolic states like NSAID use, alcohol abuse and Atrial fibrillation.Disclosure: Dr. Shah has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Hazra has nothing to disclose. Dr. Lunagariya has nothing to disclose. Dr. Jani has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Kassab has nothing to disclose. Dr. Hussain has nothing to disclose. Dr. Qure...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Shah, H., Patel, A., Patel, U., Hazra, A., Lunagariya, A., Mishra, P., Jani, V., Mehta, S., Kassab, M., Hussain, S., Qureshi, A. Tags: In-Hospital Stroke and Stroke Complications Source Type: research

Household Secondhand Smoke Exposure Confers Higher Stroke Risk and Poorer Stroke Prognosis (S42.005)
CONCLUSIONS: Household SHS is associated with a 1.5-fold increase in stroke risk and a 2-fold increase in mortality after stroke among never-smokers. While prospective studies are needed to assess causality, this study highlights the importance of obtaining SHS exposure history and counseling patients and their families on the potential impact of SHS on post-stroke outcomes.Disclosure: Dr. Lin has nothing to disclose. Dr. Ovbiagele has nothing to disclose. Dr. Markovic has nothing to disclose. Dr. Towfighi has nothing to disclose.
Source: Neurology - February 7, 2016 Category: Neurology Authors: Lin, M., Ovbiagele, B., Markovic, D., Towfighi, A. Tags: Stroke Mechanism and Modifiers Source Type: research

Moderate alcohol intake reduces risk of ischemic stroke in Korea
Conclusions: Our findings suggest that light to moderate distilled alcohol consumption may reduce the risk of ischemic stroke in Koreans.
Source: Neurology - November 30, 2015 Category: Neurology Authors: Lee, S. J., Cho, Y.-J., Kim, J. G., Ko, Y., Hong, K.-S., Park, J.-M., Kang, K., Park, T. H., Park, S.-S., Lee, K. B., Cha, J. K., Kim, D.-H., Lee, J., Kim, J.-T., Lee, J., Lee, J. S., Jang, M. S., Han, M.-K., Gorelick, P. B., Bae, H.-J., On behalf of the Tags: All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Case control studies ARTICLE Source Type: research

IV thrombolysis in patients with ischemic stroke and alcohol abuse
Conclusions: IS patients with chronic alcohol consumption or acute intoxication have decreased likelihood of receiving IVT and are not at an increased risk of associated SICH. This supports current practice guidelines, which do not list chronic alcohol consumption or acute intoxication as an exclusion criterion.
Source: Neurology - November 2, 2015 Category: Neurology Authors: Gattringer, T., Enzinger, C., Fischer, R., Seyfang, L., Niederkorn, K., Khalil, M., Ferrari, J., Lang, W., Brainin, M., Willeit, J., Fazekas, F. Tags: Alcohol, Cohort studies, Infarction ARTICLE Source Type: research

Clinical Reasoning: A 58-year-old man with right facial numbness
A 58-year-old man with a history of uncontrolled hypertension presented to the emergency department for evaluation of right facial numbness. He went to bed feeling normal and woke up with numbness and tingling in the right face limited to the right perioral area. He denied any associated neurologic symptoms or having similar experiences in the past. His medical history was significant for uncontrolled hypertension; surgical history was negative. Social history was pertinent for occasional alcohol use, but no smoking or drug use. Family history was significant for hypertension in both parents and essential tremor in his sis...
Source: Neurology - October 19, 2015 Category: Neurology Authors: Egan, K. A., Sevush-Garcy, J. L., Lukovic, E., Sherzai, A. Z., Yaghi, S. Tags: Tremor, All Cerebrovascular disease/Stroke, Infarction RESIDENT AND FELLOW SECTION Source Type: research

Watch your neighbor's garden, or Delphi's oracle for unruptured intracranial aneurysm treatment
Current management recommendations for patients with unruptured intracranial aneurysms (UIAs) include surgical clipping, endovascular coiling, or noninterventional follow-up.1 Several population-based studies and meta-analyses identified risk factors associated with aneurysm growth and rupture,2 some of which are modifiable (arterial hypertension, smoking, and excessive alcohol consumption) and some of which are not (increasing age, female sex, ethnic origin, aneurysm size, and morphology); however, no randomized controlled data exist on the potential benefit of preventive intervention for UIAs. The multinational TEAM (Tri...
Source: Neurology - September 7, 2015 Category: Neurology Authors: Bijlenga, P., Stapf, C. Tags: All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Primary prevention of stroke by a healthy lifestyle in a high-risk group
Conclusions: A healthy lifestyle is associated with a substantially reduced risk of stroke in men at higher risk of stroke.
Source: Neurology - June 1, 2015 Category: Neurology Authors: Larsson, S. C., Akesson, A., Wolk, A. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

An Unusual Cause Of Recurrent Ischemic Stroke: Trousseau's Syndrome From Gastric Cancer (P4.231)
CONCLUSIONS: Trousseau’s Syndrome must be considered in those presenting with recurrent strokes with an otherwise negative embolic work up especially in the elderly and those with cancer risk factors. It must prompt the clinician to look for an associated malignancy.Disclosure: Dr. JADEJA has nothing to disclose. Dr. Johnson has nothing to disclose. Dr. Soetanto has nothing to disclose. Dr. Nalleballe has nothing to disclose. Dr. DeNiro has nothing to disclose. Dr. Qureshi has nothing to disclose. Dr. Graber has received personal compensation for activities with Stemedica Inc., Novocure Inc., and Biogen Idec.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Jadeja, N., Johnson, J., Soetanto, A., Nalleballe, K., DeNiro, L., Qureshi, I., Graber, J. Tags: Neuro-oncology: Paraneoplastic Disorders Source Type: research

Fluctuating Mental Status and Fever of Unknown Origin (P1.030)
Conclusion: Central nervous system involvement as the initial manifestation of microscopic polyangiitis is rare and can result in a challenging clinical picture including recurrent ischemic strokes.Disclosure: Dr. Daniel has nothing to disclose. Dr. Brink has nothing to disclose. Dr. Hosley has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Daniel, A., Brink, J., Hosley, C. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Seizure as the Presenting Symptom of ICH Patient Characteristics and EEG Utilization (P3.087)
Conclusions: Patients who presented with seizure were younger, black, and a higher proportion had a history of alcohol and substance abuse compared to patients with ICH who did not present with a seizure. Only 66[percnt] of those presenting with clinical seizure underwent EEG. Despite the prevalence of subclinical seizures in ICH patients, only 19[percnt] of patients who did not present with a seizure underwent EEG. Our study suggests that there may be room for improvement on the part of stroke neurologists in the diagnosis and management seizure of ICH patients.Disclosure: Dr. Gadpaille has nothing to disclose. Dr. Albrig...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Gadpaille, A., Albright, K., Boehme, A., Alvi, M., Sands, K., Khawaja, A., Shiue, H., Harrigan, M. Tags: Cerebrovascular Disease and Interventional Neurology: Intracerebral Hemorrhage Source Type: research

The Longitudinal Relationship between Inflammatory Burden and Gait Speed is Influenced by White Matter Microstructural Characteristics: Secondary Analysis of the Health ABC Study. (I10-2A)
CONCLUSIONS: Sustained exposure to high IL-6 rather than the rate of change in IL-6 may adversely affect walking speed, potentially by influencing WM microstructural characteristics in older adults. Funding: N01-AG-6-2101, N01-AG-6-2103, N01-AG-6-2106, R01-AG028050, R01AG 027017, K07AG033174, R01-NR012459, Pittsburgh Pepper Center (P30 AG024827).Disclosure: Dr. Nadkarni has nothing to disclose. Dr. Boudreau has nothing to disclose. Dr. Lopez has received personal compensation for activities with Merz Pharma as a consultant. Dr. Aizenstein has nothing to disclose. Dr. Kritchevsky has nothing to disclose. Dr. Yaffe has recei...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Nadkarni, N., Boudreau, R., Lopez, O., Aizenstein, H., Kritchevsky, S., Yaffe, K., Studenski, S., Newman, A., Rosano, C. Tags: The Dynamic Brain in Health and Disease: Plasticity and Reprogramming Poster Presentations Source Type: research

Bilateral ascending weakness in a patient with Azygous Anterior Cerebral Artery Stroke. (P1.040)
CONCLUSION: Our patient’s clinical presentation was challenging because ascending pattern of weakness is usually seen in Acute Inflammatory Demyleinating Neuropathy or spinal cord injury. During the early stages deep tendon reflexes may be perserved in many conditions but may change on serial clinical examination. Hyperreflexia noted on follow-up examination and the absence of sensory involvemnt were the key feature suggesting a cerebral insult. Our study calls to attention to this rare vascular anomaly and its misleading clinical presentation.Disclosure: Dr. Melkumova has nothing to disclose. Dr. Noroozi has nothing...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Melkumova, E., Noroozi, J., Zisman, C., Sahni, R. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Carotid plaque thickness is positively associated with decreased bone mineral density (P2.264)
CONCLUSIONS: This study showed that increased maximum carotid IMT/plaque value is significantly associated with decreased BMD after controlling for the effects of age, gender, and BMI in acute stroke patients. Study Supported by: NoneDisclosure: Dr. Han has nothing to disclose. Dr. Park has nothing to disclose. Dr. Park has nothing to disclose. Dr. Lee has nothing to disclose. Dr. Lee has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Han, S. W., Park, J. H., Park, J. H., Lee, J. Y., Lee, K.-Y. Tags: Cerebrovascular Disease and Interventional Neurology: Carotid Disease and IMT Source Type: research

Port Harcourt Stroke Registry: A Prospective Hospital Based Study. (P1.074)
CONCLUSION: This Stroke Registry, first of its kind from this region of Nigeria presents a handy tool to track the epidemiology of stroke in this region. It will contribute to stroke prevention by providing the evidence required to formulate policies and measures required to control identified risk factors.Disclosure: Dr. Okunoye has nothing to disclose. Dr. Asekomeh has nothing to disclose. Dr. Iyagba has nothing to disclose. Dr. Onwuchekwa has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Okunoye, C., Asekomeh, G., Iyagba, A., Onwuchekwa, A. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Transient ischemic attacks in post-menopausal women with history of migraines have lower risk for subsequent ischemic strokes (P2.306)
CONCLUSIONS: The risk of ischemic stroke is lower following TIA in women with migraine history (compared with those without migraine) suggesting potentially different pathophysiology in such women.Disclosure: Dr. Rahman has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Thomas has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Rahman, H., Malik, A., Thomas, A., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Education and TIA Source Type: research

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