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Diet Clusters in Relation to Cognitive Performance and Decline in the Northern Manhattan Study (S15.003)
Conclusions:Individuals with an unhealthy western diet with limited fruits, vegetables, fish, chicken, and whole grains had worse episodic memory performance and greater decline in executive function over time.Study Supported by: NIH/NINDS (R37 NS 29993)Disclosure: Dr. Gardener has nothing to disclose. Dr. Dong has nothing to disclose. Dr. Rundek has nothing to disclose. Dr. McLaughlin has nothing to disclose. Dr. Cheung has received personal compensation for activities with Remedy as a consultant. Dr. Cheung has received research support from IBM. Dr. Elkind has received personal compensation in an editorial capacity for ...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Gardener, H., Dong, C., Rundek, T., McLaughlin, C., Cheung, K., Elkind, M., Sacco, R., Wright, C. Tags: Neuroepidemiology Source Type: research

Clinical Reasoning: A 43-year-old woman with right limb weakness
A 43-year-old woman presented with a 4-day history of right limb weakness. While biking 4 days earlier, she felt a weakness in her right hand and leg. She had a history of hypertension for more than 2 years, and was taking extended-release nifedipine tablets (40 mg) and perindopril (4 mg) daily, but her blood pressure was difficult to control (fluctuations of 150–180/90–115 mm Hg). The patient did not smoke or drink alcohol, and had no family history of similar diseases.
Source: Neurology - March 19, 2017 Category: Neurology Authors: Li, S., Zhang, J., Liu, P., Wei, R., Yuan, H., Ke, Q. Tags: Stroke in young adults RESIDENT AND FELLOW SECTION Source Type: research

Clinical Reasoning: A case of subacute cognitive decline in a 76-year-old man
A 76-year-old, right-handed man presented to our emergency department with a 3-day history of cognitive decline following a motor vehicle collision. Medical history included hypertension, atrial fibrillation, and renal dysfunction. He was a high-functioning retired advertising executive who formerly smoked cigarettes, and used neither recreational drugs nor alcohol.
Source: Neurology - September 18, 2016 Category: Neurology Authors: MacLellan, A., Breiner, A., Tang-Wai, D. F., Casaubon, L. K. Tags: Other cerebrovascular disease/ Stroke, Clinical neurology history, Clinical neurology examination, All Cognitive Disorders/Dementia RESIDENT AND FELLOW SECTION Source Type: research

Sex differences exist after intracerebral hemorrhage but may not affect outcome
While differences by race/ethnicity and age are commonly evaluated, surprisingly few studies have focused on differences in risk factor and etiology for intracerebral hemorrhage (ICH).1 Epidemiologic data have identified important differences in risk factors for ICH, with hypertension strongly associated with nonlobar, deep ICH, while factors related to cerebral amyloid angiopathy (CAA) predominate for lobar ICH.2 In the current issue of Neurology®, Roquer et al.3 found that women were more likely to have lobar ICH than men, even after adjusting for age. Since men and women had similar proportions of diagnosed CAA, ICH...
Source: Neurology - July 17, 2016 Category: Neurology Authors: Woo, D., James, M. L. Tags: Natural history studies (prognosis), Intracerebral hemorrhage EDITORIALS Source Type: research

Sex-related differences in primary intracerebral hemorrhage
Conclusions: Patients with ICH showed sex-related differences in demographic characteristics, ICH location, and vascular risk factors, but not in stroke care, 3-month mortality, or adjusted poor outcome.
Source: Neurology - July 17, 2016 Category: Neurology Authors: Roquer, J., Rodriguez-Campello, A., Jimenez-Conde, J., Cuadrado-Godia, E., Giralt-Steinhauer, E., Vivanco Hidalgo, R. M., Soriano, C., Ois, A. Tags: Natural history studies (prognosis), Intracerebral hemorrhage ARTICLE Source Type: research

Subacute decline in serum lipids precedes the occurrence of primary intracerebral hemorrhage
Conclusions: Longitudinal lipid levels differ between ICH cases and non-ICH controls, most notably for a decline in serum TC and LDL levels within 6 months preceding primary ICH, independent of statin or alcohol use. These changes in serum TC and LDL trends suggest a biological pathway that precipitates ICH occurrence. Further studies are needed to replicate these results and characterize rate of change in serum lipids as a potential biomarker of impending acute cerebral injury.
Source: Neurology - May 29, 2016 Category: Neurology Authors: Phuah, C.-L., Raffeld, M. R., Ayres, A. M., Viswanathan, A., Greenberg, S. M., Biffi, A., Rosand, J., Anderson, C. D. Tags: All Cerebrovascular disease/Stroke, Intracerebral hemorrhage ARTICLE Source Type: research

Moderate alcohol intake reduces risk of ischemic stroke in Korea
Source: Neurology - May 8, 2016 Category: Neurology Authors: Kang, B., Bae, H.-J. Tags: WRITECLICK & amp;reg; EDITOR ' S CHOICE Source Type: research

Gender Difference in Stroke: Are They Different in India? (P1.261)
Conclusion: The incidence rate was higher in men as compared to women. There were differences in risk factors and stroke type. There were no gender differences seen in stroke outcome. Acknowledgement: The Indian Council of Medical Research Task Force Project.Disclosure: Dr. Kaur has nothing to disclose. Dr. Pandian has received personal compensation for activities with Intas Pharmaceuticals and Sanofi-Aventis as an advisor. Dr. Singh has nothing to disclose. Dr. Bansal has nothing to disclose. Dr. Paul has nothing to disclose. Dr. Singla has nothing to disclose. Dr. Singh has nothing to disclose. Dr. Samuel has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kaur, P., Pandian, J., Singh, G., Bansal, R., Paul, B., Singla, M., Singh, S., Samuel, C. Tags: Cerebrovascular Disease: Health Disparities Source Type: research

Alcoholism and In-Hospital Mortality among Hemorrhagic Stroke Patients in Puerto Rico (P1.263)
Conclusions: The adjusted OR of 3.18 suggests a positive association and in-patient hemorrhagic stroke mortality. However the small sample size and low power limit the ability to delineate a clear statistical association, thereby warranting further study into this subject matter as alcoholism is a modifiable risk factor and early interventions may lower hemorrhagic stroke mortality in this population.Disclosure: Dr. Smirnoff has nothing to disclose. Dr. Moses has nothing to disclose. Dr. Zevallos has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Smirnoff, L., Moses, A., Zevallos, J. C. Tags: Cerebrovascular Disease: Health Disparities Source Type: research

Pregnancy in Advanced Age Increases the Risk of Hemorrhagic Stroke in Post-Menopausal Women. Analysis of Women's Health Initiative Study (P6.005)
Conclusions: Women with pregnancy in advanced age have a higher risk for hemorrhagic stroke in post-menopausal period.Disclosure: Dr. Qureshi has nothing to disclose. Dr. Saeed has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Degenhardt has nothing to disclose. Dr. Axt-Fliedner has nothing to disclose. Dr. Kohl has nothing to disclose. Dr. Suri has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Qureshi, A., Saeed, O., Malik, A., Degenhardt, J., Axt-Fliedner, R., Kohl, T., Suri, M. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research

Olfactory and Gustatory Dysfunction and Subsequent Stroke Risk: A Community-Based Cohort Study (P1.107)
CONCLUSIONS: Olfactory and gustatory dysfunction was associated with increased short-term future risks of stroke. Further studies with larger sample size and objective measures of olfactory and gustatory function are warranted to confirm our findings.Disclosure: Dr. Ma has nothing to disclose. Dr. Huang has nothing to disclose. Dr. Wu has nothing to disclose. Dr. Yuan has nothing to disclose. Dr. He has nothing to disclose. Dr. Chen has nothing to disclose. Dr. Wu has nothing to disclose. Dr. Gao has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Ma, C., Huang, Z., Wu, Z., Yuan, X., He, S., Chen, S., Wu, S., Gao, X. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research

Disparity in Decreased Age and Increased Incidence of Stroke in a Low-Income Chinese Population (P1.108)
Conclusions:Two disparities, which including decreased mean age of stroke onset and increased incidence, and decreased mean age of stroke onset and increased life expectancy were found in a low-income Chinese population, especially in men. These findings imply that stroke burden will continue to increase in China if the risk factors remain unchecked. Disclosure: Dr. Wang has nothing to disclose. Dr. Yang has nothing to disclose. Dr. An has nothing to disclose. Dr. Li has nothing to disclose. Dr. Zhao has nothing to disclose. Dr. Gu has nothing to disclose. Dr. Zhan has nothing to disclose. Dr. Bai has nothing to disclo...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Wang, J., Yang, L., An, Z., Li, B., Zhao, W., Gu, H., Zhan, C., Bai, L., Tu, J., Ning, X. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research

Healthy Lifestyle and Functional Outcomes from Stroke in Women (P1.111)
Conclusions: The highest versus lowest scores on the HLI were associated with reductions in risk of total and ischemic strokes with mild, moderate, and severe functional outcomes. The evidence that modest HLI scores reduced risks of total and ischemic stroke with moderate and severe functional outcomes suggests that even modest lifestyle changes may translate to reductions in risk of a disabling stroke event. Study support: CA047988, HL043851, HL080467, HL099355, UM1 CA182913Disclosure: Dr. Rist has nothing to disclose. Dr. Buring has nothing to disclose. Dr. Kase has nothing to disclose. Dr. Kurth has received personal co...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Rist, P., Buring, J., Kase, C., Kurth, T. Tags: Neuroepidemiology: Cerebrovascular Disease Source Type: research

Pattern of Acute Stroke Presentation in a Young Tertiary Hospital in South-South, Nigeria: Appraisal of Risk Factors and Clinical Outcomes (P1.118)
CONCLUSION: Stroke is associated with high mortality with patients presenting relatively young. Hemorrhagic stroke is common though ischemic stroke is still the commonest. Hypertension is the commonest risk factor. Family history of stroke and recurrent or history of previous stroke are also high.Disclosure: Dr. Obiabo has received personal compensation for activities with Novartis as a speaker.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Obiabo, Y. Tags: Cerebrovascular Disease: Epidemiology Source Type: research

Primordial Prevention of Stroke: Identifying the Determinants of Hypertension in Urban Uganda (P3.338)
Conclusions: Primordial interventions at the population and individual levels are needed to address the determinants of hypertension identified in this study. Reducing the prevalence of hypertension will have a major impact on the growing burden of stroke in Uganda and SSA. Study Supported by: NIH Fogarty International CenterDisclosure: Dr. Chin has nothing to disclose. Dr. Twinobuhungiro has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Chin, J., Twinobuhungiro, A. Tags: Neuroepidemiology: Global Health, Neuro Trauma, and CNS Inflammation Source Type: research

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