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Trends in Substance Abuse Preceding Stroke in Young Adults: An Update (S55.004)
Conclusions: Substance abuse is an important and highly prevalent risk factor for stroke in young adults. More efforts are needed to curb the increasing relationship between stroke in young adults and illicit drugs, alcohol, and smoking.Study supported by: NIH NINDS grant R01 NS30678Disclosure: Dr. De Los Rios La Rosa has nothing to disclose. Dr. Kleindorfer has received personal compensation for activities with Genentech, Inc. and for medicolegal case review. Dr. Khoury has nothing to disclose. Dr. Broderick has received research support from Significant, Genentech Inc., and Schering-Plough Corporation, and the National I...
Source: Neurology - April 9, 2014 Category: Neurology Authors: De Los Rios La Rosa, F., Kleindorfer, D., Khoury, J., Broderick, J., Alwell, K., Moomaw, C., Khatri, P., Adeoye, O., Flaherty, M., Woo, D., Eilerman, J., Ferioli, S., Kissela, B. Tags: Pediatric Stroke and Stroke in the Young Source Type: research

Risk factors for dementia with Lewy bodies: A case-control study
Conclusion: DLB risk factors are an amalgam of those for AD and PD. Smoking and education, which have opposing risk effects on AD and PD, are not risk factors for DLB; however, depression and low caffeine intake, both risk factors for AD and PD, increase risk of DLB more strongly than in either.
Source: Neurology - August 26, 2013 Category: Neurology Authors: Boot, B. P., Orr, C. F., Ahlskog, J. E., Ferman, T. J., Roberts, R., Pankratz, V. S., Dickson, D. W., Parisi, J., Aakre, J. A., Geda, Y. E., Knopman, D. S., Petersen, R. C., Boeve, B. F. Tags: Parkinson's disease/Parkinsonism, All Cognitive Disorders/Dementia, Alzheimer's disease, Dementia with Lewy bodies, Case control studies ARTICLE Source Type: research

Mild cognitive impairment: Incidence and vascular risk factors in a population-based cohort
Conclusion: Incidence of MCI increased with age regardless of definition and did not vary by sex or education. Several vascular risk factors elevated the risk of incident MCI, whether defined cognitively or functionally, but most were associated with nonamnestic MCI and CDR = 0.5. Controlling vascular risk may potentially reduce risk of MCI.
Source: Neurology - June 3, 2013 Category: Neurology Authors: Ganguli, M., Fu, B., Snitz, B. E., Hughes, T. F., Chang, C.-C. H. Tags: MCI (mild cognitive impairment), Cohort studies, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research

Prevalence, Incidence and Associated Risk Factors of Stroke in Older Adults in Havana and Matanzas Provinces, Cuba (P03.152)
CONCLUSIONS: Prevalence and incidence of stroke in this study is similar to that reported for Europe and North America, and higher than that observed in other Latin American countries. The risk profile identified includes classic risk factors plus anemia and APOE 4 genotype.Disclosure: Dr. Lombardi has nothing to disclose. Dr. Valhuerdy has nothing to disclose. Dr. Fernández has nothing to disclose. Dr. Llibre has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Llibre, J., Valhuerdy, A., Fernandez, O., Llibre, J. Tags: P03 Cerebrovascular Disease III Source Type: research

Determinants of White Matter Hyperintensity Burden in Patients with Fabry Disease (P03.171)
CONCLUSIONS: In FD subjects, the severity of cerebrovascular disease manifested by MRI-detectable WMH is greater than that of general population. WMH burden is associated with CMP in this cohort independently of age, and it may be affected by different disease processes in men and women and at different disease stages. Further studies exploring associations between WMHV, ERT, age- and gender-specific characteristics, as well as longitudinal WMH progression are warranted.Supported by: Genzyme, Sanofi Company; NIH-NINDS K23NS064052.Disclosure: Dr. Rost has received personal compensation for activities with Genzyme Corporatio...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Rost, N., Metterville, D., Cloonan, L., Fitzpatrick, K., Kanakis, A., Politei, J., Sims, K. Tags: P03 Cerebrovascular Disease III Source Type: research

Predictive Risk Factors of In-Hospital Mortality Following Acute Stroke in the United States: Data from the Nationwide Inpatient Database, 2006-2010 (P02.015)
CONCLUSIONS: The rate of in-hospital mortality is relatively high following acute stroke (8.42%). We identified multiple risk factors of in-hospital mortality in acute stroke patients. The strongest risk factor is the type stroke (hemorrhagic). The present finding suggests that patients at increased risk of mortality can be identified and additional treatment for prevention might be warranted.Disclosure: Dr. Naderi has nothing to disclose. Dr. Abcede has nothing to disclose. Dr. Al-Khoury has nothing to disclose. Dr. Mozaffar has received personal compensation for activities with California Stem Cell Inc., NuFactor, Cresce...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Naderi, N., Abcede, H., Al-Khoury, L., Mozaffar, T., Jain, V. Tags: P02 Cerebrovascular Disease II Source Type: research

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