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Specialty: Neurology
Condition: Thrombosis

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Total 3681 results found since Jan 2013.

Predictors of Stroke in Patients With Impaired Glucose Tolerance: Results From the Nateglinide and Valsartan in Impaired Glucose Tolerance Outcomes Research Trial Brief Reports
Conclusions— The most powerful predictors of stroke in patients with impaired glucose tolerance included a combination of established risk factors and novel variables, such as previous venous thromboembolism and elevated waist circumference, allowing moderately effective identification of high-risk individuals.
Source: Stroke - August 26, 2013 Category: Neurology Authors: Preiss, D., Giles, T. D., Thomas, L. E., Sun, J.-L., Haffner, S. M., Holman, R. R., Standl, E., Mazzone, T., Rutten, G. E., Tognoni, G., Chiang, F.-T., McMurray, J. J. V., Califf, R. M. Tags: Cerebrovascular disease/stroke, Risk Factors, Glucose intolerance Brief Reports Source Type: research

Variations in Acute Hospital Stroke Care and Factors Influencing Adherence to Quality Indicators in 6 European Audits Brief Reports
Conclusions— Detected variations in performance of acute stroke services were found. Differences in adherence to quality indicators might indicate population subgroups with specific needs for improving care delivery.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Wiedmann, S., Hillmann, S., Abilleira, S., Dennis, M., Hermanek, P., Niewada, M., Norrving, B., Asplund, K., Rudd, A. G., Wolfe, C. D. A., Heuschmann, P. U., on behalf of the European Implementation Score Collaboration Tags: Health policy and outcome research, Emergency treatment of Stroke, Other Stroke Treatment - Medical Brief Reports Source Type: research

Drip and Ship Thrombolytic Therapy for Acute Ischemic Stroke: Use, Temporal Trends, and Outcomes Clinical Sciences
Conclusions— Drip and ship tPA is common, used in 1 in 4 patients treated with tPA in the United States. Modest differences in mortality and symptomatic intracranial hemorrhage may be because of patient selection bias, post-tPA care differences, or unmeasured confounding. The drip and ship paradigm may facilitate widespread tPA use in patients with acute stroke.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Sheth, K. N., Smith, E. E., Grau-Sepulveda, M. V., Kleindorfer, D., Fonarow, G. C., Schwamm, L. H. Tags: Acute Cerebral Infarction, Acute Stroke Syndromes, Embolic stroke, Emergency treatment of Stroke, Thrombolysis Clinical Sciences Source Type: research

Day-by-Day Blood Pressure Variability and Functional Outcome After Acute Ischemic Stroke: Fukuoka Stroke Registry Clinical Sciences
Conclusions— These data suggest that intraindividual day-by-day BP variability during the subacute stage is associated with the 3-month functional outcome after acute ischemic stroke.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Fukuda, K., Kai, H., Kamouchi, M., Hata, J., Ago, T., Nakane, H., Imaizumi, T., Kitazono, T., on behalf of the FSR Investigators, The steering committee of the Fukuoka Stroke Registry included, Ishitsuka, Fujimoto, Ibayashi, Kusuda, Arakawa, Irie, Fujii, Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Does b1000-b0 Mismatch Challenge Diffusion-Weighted Imaging-Fluid Attenuated Inversion Recovery Mismatch in Stroke? Brief Reports
Conclusions— b1000–b0 mismatch may identify patients with ischemic stroke of the within 4.5 hours of onset with high positive predictive value, perhaps constituting an alternative imaging tissue clock.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Geraldo, A. F., Berner, L.-P., Haesebaert, J., Chabrol, A., Cho, T.-H., Derex, L., Hermier, M., Louis-Tisserand, G., Chamard, L., Klaerke Mikkelsen, I., Ribe, L., Ostergaard, L., Hjort, N., Pedraza, S., Thomalla, G., Baron, J.-C., Nighoghossian, N., Berth Tags: Cardiopulmonary Resuscitation and Emergency Cardiac Care, Magnetic Resonance Imaging (MRI), Cerebrovascular Disease/Stroke, Ischemic Stroke, Thrombosis Brief Reports Source Type: research

Genetic Drivers of von Willebrand Factor Levels in an Ischemic Stroke Population and Association With Risk for Recurrent Stroke Clinical Sciences
Background and Purpose—von Willebrand factor (vWF) plays an important role in thrombus formation during cerebrovascular damage. We sought to investigate the potential role of circulating vWF in recurrent cerebrovascular events and identify genetic contributors to variation in vWF level in an ischemic stroke population.Methods—We analyzed the effect of circulating vWF on risk of recurrent stroke using survival models in the VISP trial (Vitamin Intervention for Stroke Prevention) and the use of vWF in reclassification over traditional factors. We conducted a genome-wide association study) with imputation, based on 1000 G...
Source: Stroke - May 22, 2017 Category: Neurology Authors: Stephen R. Williams, Fang–Chi Hsu, Keith L. Keene, Wei–Min Chen, Godfrey Dzhivhuho, Joe L. Rowles III, Andrew M. Southerland, Karen L. Furie, Stephen S. Rich, Bradford B. Worrall, Michele M. Sale Tags: Biomarkers, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Enhanced Detection of Edema in Malignant Anterior Circulation Stroke (EDEMA) Score Brief Report
Conclusions—The EDEMA score identifies patients at high risk for potentially lethal malignant edema. Although it requires external validation, this scale could help expedite triage decisions in this patient population.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Charlene Jennifer Ong, Jeffrey Gluckstein, Osvaldo Laurido-Soto, Yan Yan, Rajat Dhar, Jin-Moo Lee Tags: Clinical Studies, Cerebrovascular Disease/Stroke, Ischemic Stroke, Thrombosis Brief Reports Source Type: research

Patients With Undetermined Stroke Have Increased Atrial Fibrosis Brief Report
Conclusions—The LA phenotype that was found in patients with undetermined cause supports the hypothesis that an atrial disease may be associated with stroke.
Source: Stroke - February 26, 2018 Category: Neurology Authors: Ana Catarina Fonseca, Pedro Alves, Nuno Inacio, Joao Pedro Marto, Miguel Viana–Baptista, Teresa Pinho–e–Melo, Jose M. Ferro, Ana G. Almeida Tags: Magnetic Resonance Imaging (MRI), Ischemic Stroke, Embolism Brief Reports Source Type: research

Atrial Cardiopathy and the Risk of Ischemic Stroke in the CHS (Cardiovascular Health Study) Clinical Sciences
Conclusions—In addition to clinically apparent AF, other evidence of abnormal atrial substrate is associated with subsequent ischemic stroke. This finding is consistent with the hypothesis that thromboembolism from the left atrium may occur in the setting of several different manifestations of atrial disease.
Source: Stroke - March 26, 2018 Category: Neurology Authors: Hooman Kamel, Traci M. Bartz, Mitchell S.V. Elkind, Peter M. Okin, Evan L. Thacker, Kristen K. Patton, Phyllis K. Stein, Christopher R. deFilippi, Rebecca F. Gottesman, Susan R. Heckbert, Richard A. Kronmal, Elsayed Z. Soliman, W.T. Longstreth Jr Tags: Arrhythmias, Cardiomyopathy, Echocardiography, Electrocardiology (ECG), Ischemic Stroke Original Contributions Source Type: research

Prevalence of aphasia after stroke in a hospital population in southern Brazil: a retrospective cohort study.
Conclusions: PWA may need more health care during hospitalization, because of the severity of the stroke, and their frailty. Further studies are needed to assess the direct impact of aphasia on inpatients. PMID: 31687916 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - November 4, 2019 Category: Neurology Authors: Lima RR, Rose ML, Lima HN, Cabral NL, Silveira NC, Massi GA Tags: Top Stroke Rehabil Source Type: research

Thrombolysis for Ischemic Stroke Associated With Infective Endocarditis: Results From the Nationwide Inpatient Sample Brief Reports
Conclusions— High rates of post-thrombolytic intracerebral hemorrhage and low rates of favorable outcome mandate caution in using IVT in acute ischemic stroke patients with IE.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Asaithambi, G., Adil, M. M., Qureshi, A. I. Tags: Embolic stroke, Thrombolysis Brief Reports Source Type: research

Diagnostic Yield of Pelvic Magnetic Resonance Venography in Patients With Cryptogenic Stroke and Patent Foramen Ovale Clinical Sciences
Conclusions— Among patients with ischemic stroke/transient ischemic attack and patent foramen ovale, the majority of detected DVTs were in LE veins rather than the pelvic veins and did not differ by stroke subtype. The routine inclusion of pelvic magnetic resonance venography in the diagnostic evaluation of CS warrants further prospective investigation.
Source: Stroke - July 28, 2014 Category: Neurology Authors: Liberman, A. L., Daruwalla, V. J., Collins, J. D., Maas, M. B., Botelho, M. P. F., Ayache, J. B., Carr, J., Ruff, I., Bernstein, R. A., Alberts, M. J., Prabhakaran, S. Tags: Deep vein thrombosis, Other diagnostic testing, Acute Cerebral Infarction, Embolic stroke Clinical Sciences Source Type: research

Impact of Living Alone on the Care and Outcomes of Patients With Acute Stroke Brief Reports
Conclusions— Patients living alone had delayed hospital arrival, less thrombolytic therapy, and were less likely to return home. Greater understanding of the inter-relationships among living alone, social isolation, access to stroke care, and outcomes is needed.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Reeves, M. J., Prager, M., Fang, J., Stamplecoski, M., Kapral, M. K. Tags: Acute Stroke Syndromes Brief Reports Source Type: research

Medicolegal considerations with intravenous tissue plasminogen activator in stroke: a systematic review.
Conclusion. Physicians and hospitals are at an increased risk of litigation in patients with AIS when in IV-tPA is being considered for treatment. While majority of the cases litigated were cases where tPA was not administered, only about 1 in 20 cases was litigated when complications occurred. PMID: 24083048 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Reducing haemorrhagic transformation after thrombolysis for stroke: a strategy utilising minocycline.
Authors: Blacker DJ, Prentice D, Alvaro A, Bates TR, Bynevelt M, Kelly A, Kho LK, Kohler E, Hankey GJ, Thompson A, Major T Abstract Haemorrhagic transformation (HT) of recently ischaemic brain is a feared complication of thrombolytic therapy that may be caused or compounded by ischaemia-induced activation of matrix metalloproteinases (MMPs). The tetracycline antibiotic minocycline inhibits matrix MMPs and reduces macroscopic HT in rodents with stroke treated with tissue plasminogen activator (tPA). The West Australian Intravenous Minocycline and TPA Stroke Study (WAIMATSS) aims to determine the safety and efficacy ...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research