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Specialty: General Medicine
Condition: Thrombosis

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Total 639 results found since Jan 2013.

In-thrombus thrombin secretion: a new diagnostic marker of atrial fibrillation in cryptogenic stroke
Isr Med Assoc J. 2022 Dec 1;25(12):853-854.ABSTRACTEndovascularly retrieved clots may be a potential resource for diagnosing stroke etiology. This method may influence secondary prevention treatment. We measure thrombin activity eluted by serially washing clots. We concluded that an assay measuring the change in thrombin in clots retrieved during acute stroke endovascular thrombectomy procedures may serve as a diagnostic marker of the origin of the clot. The suggested mechanism for these differences may be the clot location before its retrieval, with high blood flow causing thrombin washout in atherosclerotic clots, in con...
Source: The Israel Medical Association Journal - August 16, 2023 Category: General Medicine Authors: Ze'ev Itsekson Hayosh Eiman Abu Bandora Natalia Shelestovich Maya Nulman Mati Bakon Gal Yaniv Boris Khaitovitch Shmuel Balan Alexandra Gerasimova Tali Drori Stefan Mausbach Yvonne Schwammenthal Arnon Afek Joab Chapman Efrat Shavit Stein David Orion Source Type: research

Diabetes status and other factors as correlates of risk for thrombotic and thromboembolic events during SARS-CoV-2 infection: A nationwide retrospective case-control study using Cerner Real-World Data™
Conclusions Risk of TTE during COVID-19 illness is substantially higher in patients with diabetes. Further, risk for TTEs is higher in those with T1DM versus T2DM. Confirmation of increased diabetes-associated clotting risk in future studies may warrant incorporation of diabetes status into SARS-CoV-2 infection treatment algorithms.
Source: BMJ Open - July 9, 2023 Category: General Medicine Authors: Tallon, E. M., Gallagher, M. P., Staggs, V. S., Ferro, D., Murthy, D. B., Ebekozien, O., Kosiborod, M. N., Lind, M., Manrique-Acevedo, C., Shyu, C.-R., Clements, M. A. Tags: Open access, Diabetes and Endocrinology, COVID-19 Source Type: research

Long-term outcomes of left atrial appendage occlusion in patients with atrial fibrillation and end stage renal disease
CONCLUSIONS: Long-term outcomes of LAAO therapy may be less favorable in patients with AF undergoing dialysis, possibly because of the poor condition of patients with ESRD.PMID:37394333 | DOI:10.1016/j.jfma.2023.06.016
Source: J Formos Med Assoc - July 2, 2023 Category: General Medicine Authors: Sheng-Nan Chang Chin-Feng Tsai Ting-Tse Lin Fu-Chun Chiu Jung-Cheng Hsu Su-Kiat Chua Hsiao-Liang Cheng Li-Ting Ho Pang-Shuo Huang Jien-Jiun Chen Cho-Kai Wu Yi-Chih Wang Juey-Jen Hwang Chia-Ti Tsai Source Type: research

Pharmacological interventions for the prevention of bleeding in people undergoing definitive fixation or joint replacement for  hip, pelvic and long bone fractures
CONCLUSIONS: We cannot draw conclusions from the current evidence due to lack of data. Most published studies included in our analyses assessed the use of tranexamic acid (compared to placebo, or using different routes of administration). We identified 27 prospectively registered ongoing RCTs (total target recruitment of 4177 participants by end of 2023). The ongoing trials create six new comparisons: tranexamic acid (tablet + injection) versus placebo; intravenous tranexamic acid versus oral tranexamic acid; topical tranexamic acid versus oral tranexamic acid; different intravenous tranexamic acid dosing regimes; topical ...
Source: Cochrane Database of Systematic Reviews - June 5, 2023 Category: General Medicine Authors: Victoria N Gibbs Rita Champaneria Louise J Geneen Parag Raval Carolyn Dor ée Susan J Brunskill Alex Novak Antony Jr Palmer Lise J Estcourt Source Type: research

Ischemic stroke in the setting of supratherapeutic International Normalized Ratio following coronavirus disease 2019 infection: a case report
ConclusionsThis case report highlights the potential for thromboembolic events, including stroke, in patients with COVID-19 infection, even when receiving therapeutic anticoagulation therapy. Healthcare providers should be vigilant for signs of thrombosis in COVID-19 patients, particularly those with pre-existing risk factors. Further research is necessary to understand the pathophysiology and optimal management of thrombotic complications in COVID-19 patients.
Source: Journal of Medical Case Reports - May 31, 2023 Category: General Medicine Source Type: research

Different types of percutaneous endovascular interventions for acute ischemic stroke
CONCLUSIONS: This review did not establish any difference in safety and effectiveness between the thrombo-aspiration approach and stent-retrieval thrombectomy for treating people with AIS. Furthermore, the combined group did not show any obvious advantage over either intervention applied alone.PMID:37249304 | PMC:PMC10228464 | DOI:10.1002/14651858.CD014676.pub2
Source: Cochrane Database of Systematic Reviews - May 30, 2023 Category: General Medicine Authors: Xuesong Bai Xiao Zhang Haozhi Gong Tao Wang Xue Wang Wenjiao Wang Kun Yang Wuyang Yang Yao Feng Yan Ma Bin Yang Antonio Lopez-Rueda Alejandro Tomasello Vikram Jadhav Liqun Jiao Source Type: research

Supine headache and papilledema: A case and review of cerebral venous sinus thrombosis
Key clinical messageCerebral venous sinus thrombosis (CVST) should be on the differential for intracranial hypertension, and the preferred diagnostic tests are CT venogram or MR venography.AbstractCerebral venous sinus thrombosis (CVST) is a rare cause of stroke and is on the differential for intracranial hypertension. Non-contrast head CT is often normal. CT venogram or MR venography are the preferred diagnostic tests, as was required in our patient. We review the presentation, diagnosis, and management of CVST.
Source: Clinical Case Reports - May 5, 2023 Category: General Medicine Authors: Sachin V. Pasricha, Rajesh Bhayana, Peter E. Wu Tags: CASE IMAGE Source Type: research