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Evaluation of the JRecan device for thrombus retrieval: efficacy and safety in a swine model of acute arterial occlusion
Conclusions The JRecan is highly effective at clot removal with a favorable safety profile and merits further development as a stent retriever for the treatment of acute ischemic stroke.
Source: Journal of NeuroInterventional Surgery - April 13, 2016 Category: Neurosurgery Authors: Zhu, L., Shao, Q., Li, T., Saver, J. L., Li, L., Li, D., Zhao, W., Jiang, W. Tags: New devices Source Type: research

Stent retriever thrombectomy with the Cover accessory device versus proximal protection with a balloon guide catheter: in vitro stroke model comparison
Conclusions Application of the Cover device in this experimental model resulted in higher successful recanalization rates, no embolic events, and was more effective than use of the conventional guide catheter or BGC.
Source: Journal of NeuroInterventional Surgery - March 15, 2016 Category: Neurosurgery Authors: Mokin, M., Setlur Nagesh, S. V., Ionita, C. N., Mocco, J., Siddiqui, A. H. Tags: Basic science, Ischemic stroke Source Type: research

Reversible changes in diffusion- and perfusion-based imaging in cerebral venous sinus thrombosis
We present a patient with CVST whose abnormal findings on MRI and CT perfusion images were largely reversed after endovascular treatment.
Source: Journal of NeuroInterventional Surgery - January 13, 2016 Category: Neurosurgery Authors: Lin, N., Wong, A. K., Lipinski, L. J., Mokin, M., Siddiqui, A. H. Tags: Electronic pages Source Type: research

Comparative outcomes of carotid artery stenting for asymptomatic and symptomatic carotid artery stenosis: a single-center prospective study
Conclusions Periprocedural and long-term follow-up outcomes of CAS appear similar for ACS and SCS.
Source: Journal of NeuroInterventional Surgery - January 13, 2016 Category: Neurosurgery Authors: Mo, D., Wang, B., Ma, N., Gao, F., Miao, Z. Tags: Ischemic stroke Source Type: research

Multicenter clinical experience in over 125 patients with the Penumbra Separator 3D for mechanical thrombectomy in acute ischemic stroke
Conclusions The results suggest that the Separator 3D enables safe and effective revascularization of occluded large arteries in acute stroke intervention, leading to a high rate of functional independence at 90 days.
Source: Journal of NeuroInterventional Surgery - December 13, 2015 Category: Neurosurgery Authors: Behme, D., Kowoll, A., Mpotsaris, A., Hader, C., Hechelhammer, L., Weber, J., Weber, W. Tags: Ischemic stroke Source Type: research

The Lazarus Funnel: a blinded prospective randomized in vitro trial of a novel CE-marked thrombectomy assist device
Conclusions In this AIS embolism flow model with Solitaire thrombectomy, the Lazarus Funnel resulted in a significant increase in recanalization and significant reduction in distal emboli without increase in time to recanalization.
Source: Journal of NeuroInterventional Surgery - December 13, 2015 Category: Neurosurgery Authors: Fargen, K. M., Mocco, J., Gobin, Y. P. Tags: New devices Source Type: research

Complex decision-making in stroke: preoperative mechanical thrombectomy of septic embolus for emergency cardiac valve surgery
We report a case of cardioembolic stroke in a patient with enterococcal endocarditis, with National Institutes of Health Stroke Scale score of 3. A middle-aged patient with bacterial endocarditis exhibited mild intermittent left hemiparesis and dysarthria in the setting of severe aortic insufficiency requiring urgent aortic valve replacement. Cerebrovascular imaging revealed a partially occlusive thrombus in the M1 segment of the right middle cerebral artery, which became symptomatic during relative hypotension. Given the expected hypotension during the urgently needed aortic valve replacement, there was a significant risk...
Source: Journal of NeuroInterventional Surgery - November 13, 2015 Category: Neurosurgery Authors: Ladner, T. R., Davis, B. J., He, L., Kirshner, H. S., Froehler, M. T., Mocco, J. Tags: Electronic pages Source Type: research

Retrograde access to the posterior inferior cerebellar artery in balloon-assisted coiling of posterior inferior cerebellar artery aneurysms
Conclusions Retrograde access to the PICA to perform balloon-assisted coil embolization of proximal PICA aneurysms with or without additional stenting after coiling is safe and effective. Hypoplastic V4 segment of the contralateral vertebral artery is not a contraindication.
Source: Journal of NeuroInterventional Surgery - October 14, 2015 Category: Neurosurgery Authors: Heye, S., Stracke, C. P., Nordmeyer, H., Heddier, M., Stauder, M., Chapot, R. Tags: Hemorrhagic stroke Source Type: research

Periprocedural and mid-term technical and clinical events after flow diversion for intracranial aneurysms
Conclusions Flow diversion for intracranial aneurysms is a safe and effective treatment. Technical and clinical events are common in the perioperative period. Careful perioperative care and proper management of technical and clinical events encountered is key to achieving low morbidity and mortality. Late clinical events can occur but are unlikely to result in permanent complications.
Source: Journal of NeuroInterventional Surgery - August 12, 2015 Category: Neurosurgery Authors: Burrows, A. M., Cloft, H., Kallmes, D. F., Lanzino, G. Tags: Hemorrhagic stroke, New devices Source Type: research

O-005 preliminary results of the trevo retriever registry
ConclusionsThe Trevo Retriever Registry represents the first look at the real world data with stent retriever use in the era of clinical trials showing the overwhelming benefit of stent retrievers to treat acute ischemic stroke. Future subgroup analysis of this large cohort will help to identify areas of future research to enhance outcomes further with this treatment modality.DisclosuresR. Gupta: 1; C; Wellstar Foundation, Stryker Neurovascular, Penumbra, Covidien, Zoll. 2; C; Stryker Neurovascular, Covidien, Rapid Medical, Penumbra. R. Budzik: 2; C; Stryker Neurovascular. B. Xiang: 2; C; Stryker Neurovascular. J. English:...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Gupta, R., Budzik, R., Xiang, B., English, J., Baxter, B., Ge, S., Veznedaroglu, E. Tags: SNIS 12th Annual Meeting Oral Abstracts Source Type: research

O-009 multicentre experience with aspiration only technique for acute stroke thrombectomy using ace64
In conclusion, we are able to demonstrate the aspiration thrombectomy using the ACE64 to be an effective, easy to use, fast and safe method for treating acute stroke patients.DisclosuresA. Kowoll: None. A. Moreno: None. J. Weber: None. C. Loehr: None. G. Gal: None. H. Körner: None. A. Berlis: None. W. Weber: None. T. Lo: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Kowoll, A., Moreno, A., Weber, J., Loehr, C., Gal, G., Korner, H., Berlis, A., Weber, W., Lo, T. Tags: SNIS 12th Annual Meeting Oral Abstracts Source Type: research

P-011 initial experience with the lazarus cover device to prevent embolization in new territories during mechanical thombectomy
ConclusionsApplicationof the Cover device when performing acute stroke thrombectomy is feasible, appears to be safe, and may result in good successful recanalization rates with less embolic events.ReferenceGascou G, Lobotesis K, Machi P, et al. Stent retrievers in acute ischemic stroke: complications and failures during the perioperative period. AJNR Am J Neuroradiol 2014;35:734–40DisclosuresM. Piotin: 4; C; Lazarus Effect. B. Bartolini: None. H. Redjem: None. P. Paraschakis: None. R. Blanc: 4; C; Lazarus Effect.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Piotin, M., Bartolini, B., Redjem, H., Paraschakis, P., Blanc, R. Tags: SNIS 12th Annual Meeting Oral Poster Abstracts Source Type: research

P-013 initial experience with the ace and ace64 cerebral reperfusion catheters in the endovascular treatment of acute ischemic stroke
ConclusionIn our initial experience, the ACE/ACE64 reperfusion catheters provide a safe and effective tool for the treatment of acute ischemic stroke using direct aspiration, in which we were able to recanalize (TICI 2B/3) 96.4% of cases, achieving good clinical results.DisclosuresP. Navia: None. J. Massó: None. J. Larrea: None. E. Pardo: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Navia, P., Masso, J., Larrea, J., Pardo, E. Tags: SNIS 12th Annual Meeting Oral Poster Abstracts Source Type: research

P-015 flow stasis after the deployment of stent-retriever predicts successful final recanalization in acute stroke patients
ConclusionLoss of IFR effect during the embedding time after deployment of stent retriever was associated with successful recanalization. It may be an angiographic sign of adequate thrombus engagement with the stent retriever. This observation may be useful in order to optimize the embedding time during which a stent retriever cuts into the occlusive thrombus particularly when a new stent retriever is introduced to the clinical practice.DisclosuresS. Tateshima: 2; C; Covidien. M. Okawa: None. D. Liebeskind: None. R. Jahan: 2; C; Covidien. N. Gonzalez: None. V. Szeder: None. N. Rao: None. L. Ali: None. D. Kim: None. J. Save...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Tateshima, S., Okawa, M., Liebeskind, D., Jahan, R., Gonzalez, N., Szeder, V., Rao, N., Ali, L., Kim, D., Saver, J., Duckwiler, G. Tags: SNIS 12th Annual Meeting Oral Poster Abstracts Source Type: research

P-017 time to treatment effect on visual recovery after intra-arterial thrombolysis for acute central retinal artery occlusion
ConclusionsIAT therapy demonstrates a significant improvement in logMAR scores when comparing pre- and post-IAT therapy visual assessments. Time to treatment showed a trend towards superior improvement in patients treated in less than 4 h but this was not significant.ReferencesLange C, Feltgen N, Junker B, et al. Graefes Arch Clin Exp Ophthalmol. 2009;247(1):137–42Butz B. Acta Radiol. 2003;44(6):680–4Mercier J. J Neurorad. Epub Ahead of Print 2014-Nov 15Peterson J. Can J Neurol Sci. 2005;32:507–11Richard G. Ophthalmology 1999;106(4):768–73Schumacher M. Neuroradiology 1993;35:600–55DisclosuresP...
Source: Journal of NeuroInterventional Surgery - July 26, 2015 Category: Neurosurgery Authors: Page, P., Cambon, A., James, R. Tags: SNIS 12th Annual Meeting Oral Poster Abstracts Source Type: research

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