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Endovascular mechanical thrombectomy for cerebral venous sinus thrombosis: a systematic review
Conclusions EMT is an effective salvage therapy for refractory CVST, with a reasonable safety profile. Chemical thrombolysis, in conjunction with EMT, did not appear to result in additional harm or benefit. Further analysis is warranted to determine predictors of success after EMT for CVST.
Source: Journal of NeuroInterventional Surgery - October 13, 2017 Category: Neurosurgery Authors: Ilyas, A., Chen, C.-J., Raper, D. M., Ding, D., Buell, T., Mastorakos, P., Liu, K. C. Tags: Ischemic stroke Source Type: research

Association of clot burden score with radiographic and clinical outcomes following Solitaire stent retriever thrombectomy: analysis of the SWIFT PRIME trial
Conclusions The combination of IV thrombolysis and stent retriever thrombectomy with the Solitaire device is highly effective in achieving successful recanalization and a good clinical outcome throughout the entire range of CBS values.
Source: Journal of NeuroInterventional Surgery - September 12, 2017 Category: Neurosurgery Authors: Mokin, M., Levy, E. I., Siddiqui, A. H., Goyal, M., Nogueira, R. G., Yavagal, D. R., M Pereira, V., Saver, J. L. Tags: Ischemic stroke Source Type: research

Impact of thrombus length on recanalization and clinical outcome following mechanical thrombectomy in acute ischemic stroke
Conclusions In this study, thrombus length had no relevant impact on recanalization, neurological outcome, or intraprocedural complications following mechanical thrombectomy of middle cerebral artery occlusions. Therefore, mechanical thrombectomy with stent retrievers can be attempted with large clots.
Source: Journal of NeuroInterventional Surgery - September 12, 2017 Category: Neurosurgery Authors: Seker, F., Pfaff, J., Wolf, M., Schönenberger, S., Nagel, S., Herweh, C., Pham, M., Bendszus, M., Möhlenbruch, M. A. Tags: Ischemic stroke Source Type: research

Endovascular treatment for AIS with underlying ICAD
Conclusions Despite AIS with underlying ICAD requiring a more complex, technically demanding recanalization strategy than traditional thromboembolic AIS, it appears safe, and good outcomes are obtainable.
Source: Journal of NeuroInterventional Surgery - September 12, 2017 Category: Neurosurgery Authors: Al Kasab, S., Almadidy, Z., Spiotta, A. M., Turk, A. S., Chaudry, M. I., Hungerford, J. P., Turner, R. D. Tags: Ischemic stroke Source Type: research

Endovascular isolation of intracranial blood blister-like aneurysms with Willis covered stent
Conclusions Willis covered stent implementation may be safe and feasible for BBAs. This strategy might be a promising option for this high-risk type of aneurysm.
Source: Journal of NeuroInterventional Surgery - September 12, 2017 Category: Neurosurgery Authors: Fang, C., Tan, H.-Q., Han, H.-J., Feng, H., Xu, J.-C., Yan, S., Nie, Z.-Y., Jin, L.-J., Teng, F. Tags: Hemorrhagic stroke Source Type: research

P2Y12 hyporesponse (PRU>200) is not associated with increased thromboembolic complications in anterior circulation Pipeline
Conclusions P2Y12 hyporesponse (PRU>200) is not associated with increased periprocedural complications in a contemporary series of patients undergoing anterior circulation PED placement. Titration of antiplatelet medications to P2Y12 >200 remains unindicated and may increase the risk of hemorrhagic complications.
Source: Journal of NeuroInterventional Surgery - September 12, 2017 Category: Neurosurgery Authors: Bender, M. T., Lin, L.-M., Colby, G. P., Lubelski, D., Huang, J., Tamargo, R. J., Coon, A. L. Tags: Clinical neurology Source Type: research

Interaction between the stent strut and thrombus characterized by contrast-enhanced high-resolution cone beam CT during deployment of the Solitaire stent retriever
Conclusions CE-HRCBCT showed that the Solitaire stent retriever rarely expanded fully and the thrombus was mainly near to or outside the strut. It may not be necessary to wait a long time to allow the stent to expand fully into the thrombus because the main capture mechanism seems to be engagement of the clot between the crossings of the struts of the Solitaire.
Source: Journal of NeuroInterventional Surgery - August 17, 2017 Category: Neurosurgery Authors: Tsumoto, T., Tsurusaki, Y., Tokunaga, S. Tags: Ischemic stroke Source Type: research

O-002 Trevo registry: sub-group analysis of passes and devices needed to achieve recanalization
Conclusions The Trevo Retriever Registry represents the first look at real world data with stent retriever use in the era of clinical trials showing the overwhelming benefit of stent retrievers to treat acute ischemic stroke. This data represents real world use of the Trevo Retriever in regards to the typical number of passes and devices required for recanalization. Disclosures M. Binning: None. E. Veznedaroglu: 2; C; stryker. B. Baxter: None. J. English: None. R. Budzik: None. B. Bartolini: None. D. Liebeskind: None. A. Krajina: None. R. Gupta: None. R. Nogueira: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Binning, M., Veznedaroglu, E., Baxter, B., English, J., Budzik, R., Bartolini, B., Liebeskind, D., Krajina, A., Gupta, R., Nogueira, R. Tags: Oral Abstracts Source Type: research

O-012 Acute clot formation on the surface of flow diverters can be reduced by using phosphoryl-choline surface modification
Conclusion Our preliminary study supported our hypothesis that using phosphoryl-choline surface modified flow diverter can be useful to decrease the occurrence of micro-clot formation, especially post-angioplasty. Importantly, S-PED reduced clot formation at the origin of covered side-branches. References . AJNR 2015;36:98–107. . J. Neurosurg 2016;1–6. Disclosures M. Marosfoi: None. F. Clarencon: None. E. Langan: None. R. King: None. O. Brooks: None. T. Tamura: None. M. Gounis: 1; C; Medtronic Neurovascular. A. Puri: 1; C; Medtronic Neurovascular.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Marosfoi, M., Clarencon, F., Langan, E., King, R., Brooks, O., Tamura, T., Gounis, M., Puri, A. Tags: Oral Abstracts Source Type: research

O-030 Aspiration catheter with extension tip exhibits improved suction
Conclusion The Mi-R4Q demonstrates a substantial increase in aspiration catheter capability by applying known relationships in Fluid Dynamics to more effectively convey vacuum and aspirate fluid than anything else currently on the market. Simulated use validates effectiveness of design and paves the way for in-vivo study. Disclosures A. Halaszyn: 1; C; MIVI Neuroscience Inc. A. Berenstein: 6; C; MIVI Neuroscience Inc.. T. Shigematsu: None. P. Coletti: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Halaszyn, , Berenstein, A., Shigematsu, T., Coletti, P. Tags: Oral Abstracts Source Type: research

O-035 Risk factors for delayed deterioration after cerebral venous thrombosis: a model to identify patients for early aggressive endovascular therapy
Conclusion We found that decreased mental status, seizure activity, papilledema, number of involved sinuses, sodium level, and platelet level to be the most important factors in predicting deterioration after CVT. This group may represent a subset of patients in who early thrombectomy may be considered. Further prospective trials are needed to confirm this hypothesis. Abstract O-035 Figure 1Odds ratios of clinical deterioration for the predictors of the multivariable logistic regression model. To get the ratio of deterioration for catergory 1 versus 0, one needs to take the reciprocal Disclosures S. Bushnaq: None. T. ...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Bushnaq, S., Thacker, T., Abbas, M., Qeadan, F., Carlson, A. Tags: Oral Abstracts Source Type: research

E-018 Post endovascular treatment of acute vertebro-basilar stroke: anticoagulation versus antiplatelet therapy
Conclusion Preliminary analysis of this ongoing systematic review did not show any differences in outcome or hemorrhagic complications in patients with AVBS on APT versus ACT post intervention. Either modality of treatment was superior to no treatment with a higher risk of hemorrhagic complications. Disclosures M. Weber: None. N. Khan: None. F. Siddiqui: None. J. Blessman: None. A. Elias: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Weber, M., Khan, N., Siddiqui, F., Blessman, J., Elias, A. Tags: Electronic Poster Abstracts Source Type: research

E-077 Laboratory analogs of challenging thromboemboli in acute ischemic stroke
Conclusion Thrombus analogs with mechanical characteristics similar to those of challenging clinical thrombi were successfully developed. The calcium apatite thrombus analog was found to be stiffer than the fibrin-rich thrombus analog. References . Saver JL et al: Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 2015, 372(24):2285–2295. . Dorn F et al: Endovascular treatment of acute intracerebral artery occlusions with the solitaire stent: single-centre experience with 108 recanalization procedures. Cerebrovasc Dis 2012, 34(1):70–77. Disclosures: J. Chueh: None. J....
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Chueh, J., Litchman, J., Arslanian, R., Carniato, S., Rex, D., Howk, M., Gounis, M., Puri, A. Tags: Electronic Poster Abstracts Source Type: research

E-082 Aggressive endovascular management of massive dural venous sinus thrombosis in the setting of acute myelogenous leukemia
Conclusion DVST is an uncommon cause of stroke. The appropriate diagnosis is imperative as the treatment for DVS is vastly different from the treatment of arterial stroke. Patients who suffer from DVST have a good prognosis and often achieve complete recovery. This case demonstrates the utility of more invasive endovascular treatments for extreme cases that fail to improve, or worsen, following a trial of conventional care. When thrombolysis and thrombectomy alone were not successful, stenting of an underlying dural sinus stenosis was ultimately required for successful recanalization. Disclosures: D. Leonard: None. A. Ha...
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Leonard, D., Haider, A., Thakur, R., Gottlich, C., Khan, U., Layton, K. Tags: Electronic Poster Abstracts Source Type: research

E-088 Investigation of safety termination of antiplatelet therapy after lvis stent-assisted cerebral aneurysm coiling
Conclusion Termination of AT at 3 months postoperatively did not result in ischemic events among patients who underwent LSAC. Neointimal formation of Lvis stent may be a criterion for termination of AT without increasing the risk of ischemic event. Disclosures: K. Takayama: None. K. Myouchin: None. T. Wada: None. S. Kurokawa: None. K. Kichikawa: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2017 Category: Neurosurgery Authors: Takayama, K., Myouchin, K., Wada, T., Kurokawa, S., Kichikawa, K. Tags: Electronic Poster Abstracts Source Type: research

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