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Specialty: Internal Medicine
Condition: Thrombosis

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Total 353 results found since Jan 2013.

Stent placement ‘effective alternative to IVT in stroke patients’
In stroke patients in whom intravenous thrombolysis is either contraindicated or has failed, intra-arterial revascularization with cerebral angioplasty and stent placement is an effective and well-tolerated treatment, say Czech researchers.
Source: MedWire News - Thrombosis - December 31, 2012 Category: Internal Medicine Source Type: news

Review: Contemporary oral contraceptives are associated with venous thromboembolism and stroke.
PMID: 24343404 [PubMed - in process]
Source: Annals of Internal Medicine - December 17, 2013 Category: Internal Medicine Authors: Deloughery T Tags: Ann Intern Med Source Type: research

Novel anticoagulants in patients with mechanical heart valves
Commentary on: Eikelboom JW, Connolly SJ, Brueckmann M, et al.. Dabigatran versus warfarin in patients with mechanical heart valves. N Engl J Med 2013;369:1206. Context Novel anticoagulants (including the direct thrombin inhibitor dabigatran etixilate) and oral factor Xa inhibitors have similar or superior efficacy and safety to warfarin for reducing thromboembolic stroke in patients with atrial fibrillation, and for prevention of deep venous thrombosis. Eikelboom and colleagues set out to examine whether these novel anticoagulants could be used as an alternative to warfarin in patients with mechanical heart valves. Method...
Source: Evidence-Based Medicine - May 19, 2014 Category: Internal Medicine Authors: Stewart, R. A. H. Tags: Drugs: cardiovascular system, Stroke, Venous thromboembolism Therapeutics Source Type: research

Risk of thromboembolism and fatal stroke in patients with psoriasis and non‐valvular atrial fibrillation: a Danish nationwide cohort study
ConclusionsIn patients with non‐valvular atrial fibrillation not treated with oral anticoagulation severe psoriasis was associated with increased risk of thromboembolism. In these patients CHA2DS2VASc underestimated the risk of thromboembolism.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - May 1, 2014 Category: Internal Medicine Authors: Ole Ahlehoff, Gunnar Gislason, Morten Lamberts, Fredrik Folke, Jesper Lindhardsen, Carsten Toftager Larsen, Christian Torp‐Pedersen, Peter Riis Hansen Tags: Original Article Source Type: research

Risk of thromboembolism and fatal stroke in patients with psoriasis and nonvalvular atrial fibrillation: a Danish nationwide cohort study
ConclusionsIn patients with nonvalvular atrial fibrillation not treated with oral anticoagulation, severe psoriasis was associated with increased risk of thromboembolism. In these patients, CHA2DS2VASc underestimated the risk of thromboembolism.
Source: Journal of Internal Medicine - June 13, 2014 Category: Internal Medicine Authors: O. Ahlehoff, G. Gislason, M. Lamberts, F. Folke, J. Lindhardsen, C. T. Larsen, C. Torp‐Pedersen, P. R. Hansen Tags: Original Article Source Type: research

Large thrombus entrapped in a patent foramen ovale complicated by stroke and pulmonary embolism.
Authors: Szymańska UA, Rosiak M, Rozbicka J, Kosior DA PMID: 26200927 [PubMed - as supplied by publisher]
Source: Polskie Archiwum Medycyny Wewnetrznej - July 24, 2015 Category: Internal Medicine Tags: Pol Arch Med Wewn Source Type: research

ISC: Imaging supplants clocks for targeting stroke reperfusion
LOS ANGELES – Can brain imaging surpass the clock for identifying acute ischemic stroke patients who will benefit from thrombolytic or thrombectomy treatment? That’s what experts now envision, based...
Source: Internal Medicine News - February 26, 2016 Category: Internal Medicine Source Type: research

New reversal agent for factor Xa inhibitors shows promise
Commentary on: Siegal DM, Curnette JT, Connolly SJ, et al.. Andexanet alfa for the reversal of Factor Xa inhibitor activity. N Engl J Med 2015;373:2413–24. Context Direct oral anticoagulants (DOACs) have emerged as alternatives to vitamin K-antagonists (eg, warfarin) for the long-term management of stroke prevention for non-valvular atrial fibrillation or venous thromboembolic disease. Favourable side-effect profiles and absence of therapeutic monitoring are important benefits of these newer agents. Warfarin is readily reversed with fresh frozen plasma (FFP) or prothrombin complex concentrates.1 The first reversal ag...
Source: Evidence-Based Medicine - May 22, 2016 Category: Internal Medicine Authors: Ghadimi, K., Welsby, I. J. Tags: Clinical trials (epidemiology), Immunology (including allergy), Drugs: cardiovascular system, Stroke, Venous thromboembolism, Unwanted effects / adverse reactions Therapeutics/Prevention Source Type: research

Restarting oral anticoagulation among patients with atrial fibrillation with gastrointestinal bleeding was associated with lower risk of all-cause mortality and thromboembolism
This study assesses risks of all-cause mortality, thromboembolism, major bleeding and recurrent GIB associated with resuming antithrombotic treatment after GIB among patients with AF. Methods This prospective cohort study included non-valvular patients with AF who experienced GIB while receiving single or combined antithrombotic treatment with an antiplatelet and/or anticoagulant in a Danish cohort from 1996...
Source: Evidence-Based Medicine - July 25, 2016 Category: Internal Medicine Authors: Qureshi, W. T., Nasir, U. Tags: EBM Prognosis, Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Drugs: CNS (not psychiatric), Stroke, Venous thromboembolism, Pulmonary embolism Source Type: research

Early ST-segment elevation acute myocardial infarction after thrombolytic therapy for acute ischemic stroke: A case report
We report a case of STEMI occurring 40 minutes after thrombolytic therapy for AIS and discuss the possible mechanisms and therapeutic approaches. Patient concerns: A 87-year-old woman with a history of arterial hypertension was admitted for acute onset of right-sided limb weakness 2 hours before arrival at the emergency department. Forty minutes after intravenous recombinant tissue plasminogen activator (i.v. rtPA) administration for AIS, STEMI occurred (signaled by a third-degree atrioventricular block). Diagnoses: The diagnoses were AIS and STEMI. Coronary angiography confirmed right coronary artery occlusion. ...
Source: Medicine - December 1, 2018 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Association of clinical and laboratory variables with in-hospital incidence of deep vein thrombosis in patients after acute ischemic stroke: A retrospective study
Deep vein thrombosis (DVT) is a serious complication in patients with acute ischemic stroke (AIS). Early prediction of DVT could enable physicians to perform a proper prevention strategy. We analyzed the association of clinical and laboratory variables with DVT to evaluate the risk of DVT in patients after AIS. AIS patients admitted to the Changsha Central Hospital between January 2017 and December 2019 with length of stay in hospital ≥7 days were included. Clinical and laboratory variables for DVT at baseline were collected, and the diagnosis of DVT was confirmed by ultrasonography. Independent factors were developed...
Source: Medicine - February 12, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Chinese herbal injections combined with rt-PA intravenous thrombolysis for acute ischemic stroke: A systematic review and meta-analysis protocol
Conclusion: The conclusion of the meta-analysis will provide a basis for judging whether CHIs combined with intravenous thrombolysis is an effective measure for the treatment of AIS. Ethics and dissemination: Ethical approval is not needed because this study will be based on data that already published. We will publish the findings of this study in a peer-reviewed journal and related conferences. PROSPERO registration number: CRD42020215546.
Source: Medicine - March 12, 2021 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Clinical Experience of Percutaneous Patent Foramen Ovale Closure using the Amplatzer PFO Occluder in Japanese Patients to Prevent the Recurrence of Cryptogenic Stroke
Conclusion: Percutaneous closure using Amplatzer PFO occluder is a safe procedure for Japanese patients However, further investigations with a larger sample and longer follow-up are needed to confirm this result.PMID:34024855 | DOI:10.2169/internalmedicine.7188-21
Source: Internal Medicine - May 24, 2021 Category: Internal Medicine Authors: Hiroya Takafuji Kotaro Obunai Yu Makihara Nahoko Kato Hiroyuki Watanabe Source Type: research