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Specialty: Internal Medicine
Condition: Patent Foramen Ovale

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Total 47 results found since Jan 2013.

Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis.
Conclusion: In patients with PFO and cryptogenic stroke, transcatheter device closure decreases risk for recurrent stroke compared with medical therapy alone. Because recurrent stroke rates are low even with medical therapy alone and PFO closure might affect AF risk, shared decision making is crucial for this treatment. Primary Funding Source: None. PMID: 29310136 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - January 9, 2018 Category: Internal Medicine Authors: Shah R, Nayyar M, Jovin IS, Rashid A, Bondy BR, Fan TM, Flaherty MP, Rao SV Tags: Ann Intern Med Source Type: research

Residual Shunt After Patent Foramen Ovale Closure and Long-Term Stroke Recurrence.
CONCLUSION: Among patients undergoing PFO closure to prevent future stroke, the presence of residual shunt, particularly a moderate or large residual shunt, was associated with an increased risk for stroke or TIA recurrence. PRIMARY FUNDING SOURCE: National Institutes of Health. PMID: 32422058 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - May 11, 2020 Category: Internal Medicine Authors: Deng W, Yin S, McMullin D, Inglessis-Azuaje I, Elmariah S, Hung J, Lo EH, Palacios IF, Buonanno FS, Ning M Tags: Ann Intern Med Source Type: research

Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis.
Conclusion: Compared with medical treatment, PFO closure prevents recurrent stroke and TIA but increases the incidence of AF or AFL in PFO carriers with cryptogenic stroke. Primary Funding Source: Italian Ministry of Education, University and Research (MIUR). (PROSPERO: CRD42017074686). PMID: 29310133 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - January 9, 2018 Category: Internal Medicine Authors: De Rosa S, Sievert H, Sabatino J, Polimeni A, Sorrentino S, Indolfi C Tags: Ann Intern Med Source Type: research

Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism: A Prospective Cohort Study.
Conclusion: Frequency of recent ischemic stroke in patients with symptomatic PE was higher in patients with PFO than in those without PFO. This finding supports the hypothesis that paradoxical embolism is an important mechanism of ischemic stroke in patients with PFO. Primary Funding Source: French Ministry of Health. PMID: 31060047 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - May 6, 2019 Category: Internal Medicine Authors: Le Moigne E, Timsit S, Ben Salem D, Didier R, Jobic Y, Paleiron N, Le Mao R, Joseph T, Hoffmann C, Dion A, Rousset J, Le Gal G, Lacut K, Leroyer C, Mottier D, Couturaud F Tags: Ann Intern Med Source Type: research

Closure of a patent foramen ovale with a device does not offer a greater benefit than medical therapy alone for the prevention of recurrent cerebrovascular events
Commentary on: Furlan AJ, Reisman M, Massaro J, et al.. CLOSURE I Investigators. Closure or medical therapy for cryptogenic stroke with patent foramen ovale. N Engl J Med 2012;366:991–9. Context Stroke can rarely be caused by paradoxical emboli passing from the right side of the circulatory system to the left side. Case reports have shown that the most common site of right to left shunt is the patent foramen ovale (PFO), and case control studies have shown a higher prevalence of PFO in patients with cryptogenic stroke as compared to stroke victims with a known cause or non-stroke controls. Therefore, the question ari...
Source: Evidence-Based Medicine - January 17, 2013 Category: Internal Medicine Authors: Mattle, H. P., Mono, M.-L. Tags: Smoking and tobacco, Epidemiologic studies, Drugs: cardiovascular system, Stroke, Hypertension, Lipid disorders, Arrhythmias, Health education, Smoking Therapeutics Source Type: research

Oral anticoagulants vs antiplatelets in cryptogenic stroke with potential cardiac emboli: Meta-analysis
CONCLUSIONS: OACs compared with antiplatelet therapies were associated with a reduced recurrent ischemic stroke risk and OACs might be a viable non-procedural alternative in patients with cryptogenic stroke and potential cardiac emboli.PMID:34419310 | DOI:10.1016/j.ejim.2021.08.002
Source: European Journal of Internal Medicine - August 22, 2021 Category: Internal Medicine Authors: Wen-Yi Huang Bruce Ovbiagele Meng Lee Source Type: research

24-hour ambulatory blood pressure and cryptogenic ischemic stroke in young adults
CONCLUSIONS: Non-dipping patterns of BP were associated with CIS in the absence of a PFO but not in the absence of hypertension. This may reflect differing pathophysiology underlying CIS in patients with versus without a PFO. Due to limitations of the study, results regarding absolute ABP levels should be interpreted with caution.Key MessagesNocturnal non-dipping patterns of blood pressure were associated with cryptogenic ischemic stroke except in participants with a patent foramen ovale and in those without hypertension by any definition, which may indicate differing pathophysiology underlying cryptogenic ischemic stroke ...
Source: Annals of Medicine - April 23, 2023 Category: Internal Medicine Authors: Lauri Tulkki Nicolas Martinez-Majander Petri Haapalahti Heli Tolppanen Juha Sinisalo Olli Repo Tomi Sarkanen Heikki Numminen Essi Ry ödi Pauli Ylikotila Risto O Roine Riikka Lautam äki Antti Saraste Tuuli Miettinen Jaana Autere Pekka J äkälä Marja He Source Type: research

Patent foramen ovale and cryptogenic stroke: from studies to clinical practice
ConclusionAfter many years of interest on PFO and many concluded studies, there are still no definitive data. However, we are on good track for an appropriate management of PFO patients and cryptogenic stroke.
Source: International Journal of Clinical Practice - July 6, 2016 Category: Internal Medicine Authors: K. Savino, M. Maiello, F. Pelliccia, G. Ambrosio, P. Palmiero Tags: Systematic Review Source Type: research

Patent foramen ovale closure or medical therapy for secondary prevention of cryptogenic stroke: An update meta-analysis of randomized controlled trials
Conclusion: PFO closure, as compared with medical therapy, was associated with decreased risk of recurrent stroke and increased risk of atrial fibrillation in cryptogenic stroke patients with PFO.
Source: Medicine - August 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Successful lysis in a stroke following endovenous laser ablation and extensive miniphlebectomy of varicose veins.
This report describes a successful lysis in a patient with an ischemic stroke associated with bilateral endovenous heat-induced thrombosis class I after endovenous laser ablation of both great saphenous vein and extensive miniphlebectomy in a patient with an unknown patent foramen ovale. PMID: 26447137 [PubMed - as supplied by publisher]
Source: Phlebology - October 6, 2015 Category: Internal Medicine Authors: Spinedi L, Staub D, Uthoff H Tags: Phlebology Source Type: research

Dilemma in approach to stroke in sickle cell disease patient: A case report
Conclusion: Recommendations need to be put in place regarding screening for PFO in patients with SCD, in addition to highlighting issues of whether screening needs to be done in patients who have not developed stroke, and if PFO were to be found, what would be the best management approach and how will prognosis be affected.
Source: Medicine - July 15, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Adding patent foramen ovale closure to antiplatelet therapy reduced stroke after cryptogenic stroke.
Authors: PMID: 29335719 [PubMed - in process]
Source: Annals of Internal Medicine - January 16, 2018 Category: Internal Medicine Tags: Ann Intern Med Source Type: research

Adding patent foramen ovale closure to antiplatelet drugs reduced ischemic stroke after cryptogenic stroke.
PMID: 29335718 [PubMed - in process]
Source: Annals of Internal Medicine - January 16, 2018 Category: Internal Medicine Authors: Alberts MJ Tags: Ann Intern Med Source Type: research