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P136/338 Intracranial vessel wall imaging - A tertiary centre initial experience
ConclusionOur centre’s experience recognises the role of MR-VWI in the imaging of ischaemic stroke, as well as its potential in management of acute unstable intracranial aneurysm. Clinical-radiological correlation remains imperative and emphasis is placed on understanding the potential technical pitfall of MR-VWI.Disclosure of InterestNothing to disclose for all authors
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Chung, R.-E., Kow, K., Qayyum, N., Joseph, J., Jadun, C. K., Nayak, S., Srivastava, S., Majeed, U., Hashim, Z., Tsang, K. Tags: 2.1 ISCHEMIC - Logistics Source Type: research

Diagnostic Value of Vessel Wall Imaging to Determine the Timing of Extracranial ‒Intracranial Bypass for Moyamoya Syndrome Associated with Active Sjögren's Syndrome: A Case Report
Conclusions Our findings emphasize the diagnostic value of contrast-enhanced MR-VWI in monitoring the effect of immunosuppressive therapy for the major cerebral artery vasculitis and in determining the timing of EC–IC bypass as a “rescue” treatment for moyamoya syndrome associated with active Sjögren's syndrome. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Journal of Neurological Surgery Part A: Central European Neurosurgery - May 23, 2023 Category: Neurosurgery Authors: Shindo, Takafumi Ito, Masaki Sugiyama, Taku Okuyama, Tomohiro Kono, Michihito Atsumi, Tatsuya Fujimura, Miki Tags: Case Report Source Type: research

E-021 Pathophysiology, stroke types, collateral formation and aneurysms in moyamoya disease/moya moya syndrome
ConclusionsMMD is presented most commonly with ischemic stroke in the pediatric age group and with hemorrhagic stroke in the adult age group. MMD-associated intracranial aneurysms frequently occur in patients presenting with hemorrhagic unilateral MMD and are associated with an extremely high rate of rupture. Long-standing hemodynamic stress might contribute to the formation of an aneurysm.Disclosures S. Ahmad: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Ahmad, S. Tags: Electronic poster abstracts Source Type: research

E-060 Endovascular treatment for intracranial giant cell arteritis with angioplasty, stenting, and intra-arterial calcium channel blockers
ConclusionsEndovascular treatment, including PTA (with or without stenting) and CCB infusion, may be effective in medically-refractory GCA with intracranial arterial stenosis but complication rates are considerable. The efficacy of CCB monotherapy implicates vascular smooth muscle dysfunction in the pathogenesis of intracranial GCA.Calcium-channel blocker infusion as monotherapy for intracranial giant cell arteritis. Pre-treatment angiography (lateral right internal carotid artery projection) shows severe focal supraclinoid ICA stenosis (curved white arrow, 1A). Post-verapamil infusion (20mg, 15 min delay) angiogram (1B) s...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Caton, M., Mark, I., Baker, A., Narsinh, K., Halbach, V., Hetts, S., Cooke, D., Higashida, R., Dowd, C., Smith, W., Amans, M. Tags: Electronic poster abstracts Source Type: research

Ischemic stroke as initial manifestation of Takayasu's arteritis
We present a case report where the first clinical manifestation of a large vessel vasculitis occurred within the central nervous system.
Source: Interdisciplinary Neurosurgery - April 10, 2018 Category: Neurosurgery Source Type: research

Case presentation: the dancing man from sierra leone
Discussion Making this diagnosis is challenging, as brain imaging often shows non specific changes and blood results are usually normal. CSF may reveal raised proteins and WBCs. A high index of suspicion is required to arrange a brain biopsy as this confirms the diagnosis.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Al-Rifai, M. S., Salek-Haddadi, A. Tags: Immunology (including allergy), Neuroimaging, Stroke, Radiology, Drugs: musculoskeletal and joint diseases, Vascularitis, Surgical diagnostic tests ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

E-043 Reversible Cerebral Vasoconstriction Syndrome: Non-invasive Imaging Findings and Angiographic Evaluation
We present indirect findings on non-invasive imaging, such as transient cerebral edema, convexal subarachnoid hemorrhage, intraparenchymal hemorrhage and cerebral. Direct signs of single or multivessel arterial vasoconstriction are seen on CTA, MRA and confirmed on DSA. Reversibility of the vasoconstriction is demonstrated after intra-arterial administration of calcium channel blocker. Conditions such as diffuse atherosclerotic arterial narrowing, vasculitis, posterior reversible encephalopathy, cerebral edema secondary to venous congestion and vasospasm secondary to aneurysmal subarachnoid hemorrhage were among the pathol...
Source: Journal of NeuroInterventional Surgery - July 28, 2016 Category: Neurosurgery Authors: de Macedo Rodrigues, K., Hito, R., Takhtani, D., Lozano, J., Wakhloo, A., Puri, A. Tags: Electronic poster abstracts Source Type: research

Fulminant vasculitis associated with extracranial dissections and occlusion, ischemic strokes, and aneurysm rupture: Case report and review of the literature
Central nervous system (CNS) vasculitis has multiple presentations, including stroke, seizures, cranial nerve palsies, and encephalopathy.
Source: World Neurosurgery - April 21, 2016 Category: Neurosurgery Authors: Osama Jamil, Philipp Taussky, Richard H. Schmidt, Min S. Park Tags: Case Report Source Type: research

Stroke associated with giant cell arteritis: a population-based study
Conclusions This population-based study demonstrated that GCA-related stroke essentially affects the vertebrobasilar territory and mainly occurs in old men with associated vascular risk factors. Although rare, GCA symptoms must be searched for in elderly patients with stroke, and optimal vascular prevention must be conducted carefully in patients with GCA with a high vascular risk before initiating GCA treatment.
Source: Journal of Neurology, Neurosurgery and Psychiatry - January 14, 2015 Category: Neurosurgery Authors: Samson, M., Jacquin, A., Audia, S., Daubail, B., Devilliers, H., Petrella, T., Martin, L., Durier, J., Besancenot, J.-F., Lorcerie, B., Giroud, M., Bonnotte, B., Bejot, Y. Tags: Immunology (including allergy), Stroke, Vascularitis Cerebrovascular disease Source Type: research

Probable bilateral posterior cerebral artery dissection
We present the clinical features of this highly unusual case and discuss the radiological findings. In the absence of another identified cause and given the proximity to tentorium, we presume the cause is bilateral PCA dissection.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 9, 2014 Category: Neurosurgery Authors: Lam, D., Siripurapu, R., H, S., Punter, M. Tags: Abstracts Source Type: research

Moving to connective tissue disease
We present an approach to the neurological presentations of CTD and reveal possible manifestations and important treatment considerations.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 9, 2014 Category: Neurosurgery Authors: Singh, A., Sivagnanasundaram, J., Doshi, A., Kock, N. Tags: Abstracts Source Type: research

Circulating endothelial cells as potential diagnostic biomarkers in primary central nervous system vasculitis
Conclusions For the first time it is shown that CEC are significantly elevated in patients with active PCNSV in contrast to other pathologies associated with brain infarction and correlate with disease activity. Sensitivity and specificity of the method for diagnosing PCNSV and the use of the method for treatment monitoring should be addressed in future prospective studies with a larger patient group.
Source: Journal of Neurology, Neurosurgery and Psychiatry - June 9, 2013 Category: Neurosurgery Authors: Deb, M., Gerdes, S., Heeren, M., Lambrecht, J., Worthmann, H., Goldbecker, A., Tryc, A. B., Lovric, S., Schulz-Schaeffer, W., Brandis, A., Dengler, R., Weissenborn, K., Haubitz, M. Tags: Immunology (including allergy), Stroke, Radiology, Vascularitis, Surgical diagnostic tests Cerebrovascular disease Source Type: research

Decompressive hemicraniectomy without clot evacuation in dominant-sided intracerebral hemorrhage with ICP crisis.
Conclusions Decompressive hemicraniectomy without clot evacuation appears feasible in patients with large ICH and deserves further investigation, preferably in a randomized controlled setting. PMID: 23634923 [PubMed - in process]
Source: Neurosurgical Focus - May 1, 2013 Category: Neurosurgery Authors: Heuts SG, Bruce SS, Zacharia BE, Hickman ZL, Kellner CP, Sussman ES, McDowell MM, Bruce RA, Connolly ES Tags: Neurosurg Focus Source Type: research

Thrombolysis for acute stroke in patients with vasculitis: Case report and literature discussion
We present a case of ICH after tPA administration in a patient with known Churg–Strauss Syndrome (CSS) and discuss the implications of thrombolysis in patients with vasculitis.
Source: Clinical Neurology and Neurosurgery - June 20, 2012 Category: Neurosurgery Authors: Pooia Fattahi, Faheem Sheriff, Nandakumar S. Narayanan, David M. Greer, Joseph Schindler Tags: Case Reports Source Type: research