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History of cardiovascular disease and cardiovascular biomarkers are associated with 30-day mortality in patients with hip fracture
ConclusionPreexisting CVD was associated with increased 30-day mortality after a hip fracture. Furthermore, high levels of NT-proBNP and low levels of HDL cholesterol were associated with increased 30-day mortality.
Source: Osteoporosis International - July 3, 2019 Category: Orthopaedics Source Type: research

Decreased physical health-related quality of life —a persisting state for older women with clinical vertebral fracture
ConclusionsClinical vertebral fracture was associated with lower self-rated physical HRQoL, for up to 18.9  years after time of fracture.
Source: Osteoporosis International - June 20, 2019 Category: Orthopaedics Source Type: research

Saving bones without risking brain —bisphosphonates and risk of stroke: matched case-control study
ConclusionsWe found no association between bisphosphonate treatment and risk of stroke, after adjusting for other confounders.
Source: Osteoporosis International - June 16, 2019 Category: Orthopaedics Source Type: research

The Design and Validation of a New Algorithm to Identify Incident Fractures in Administrative Claims Data
This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - June 5, 2019 Category: Orthopaedics Authors: Nicole C. Wright, Shanette G. Daigle, Mary E. Melton, Elizabeth S. Delzell, Akhila Balasubramanian, Jeffrey R. Curtis Tags: ORIGINAL ARTICLE Source Type: research

25(OH) vitamin D and functional outcomes in older adults admitted to rehabilitation units: the safari study
ConclusionsIn our study, 25(OH)D concentration showed a positive association with functional outcomes at 3  months. The association is stronger below the usual cutoff for “deficiency.” Dosage of 25(OH)D concentration may help identify geriatric rehabilitation patients at risk for a worse functional recovery.
Source: Osteoporosis International - January 16, 2019 Category: Orthopaedics Source Type: research

Vascular Involvement in Axial Spondyloarthropathies
Publication date: Available online 19 May 2018Source: Joint Bone SpineAuthor(s): Clément Prati, Céline Demougeot, Xavier Guillot, Maxime Sondag, Frank Verhoeven, Daniel WendlingAbstractAnkylosing spondylitis (AS) is a chronic inflammatory joint disease that involves the entheses, causing inflammatory pain and functional impairments. Patients may experience extraarticular manifestations such as uveitis, psoriasis, and inflammatory bowel disease. These, together with the increased risk of cardiovascular disease and osteoporosis and the development of spinal fusion, are the main determinants of adverse disease outcomes. As ...
Source: Joint Bone Spine - July 10, 2018 Category: Orthopaedics Source Type: research

Predictors of near-term fracture in osteoporotic women aged ≥65 years, based on data from the study of osteoporotic fractures
ConclusionsSeveral clinical characteristics predictive of hip and non-vertebral fracture within a 1-year follow-up period among elderly women with osteoporosis were identified, and a subset of those for hip fracture was incorporated into a risk assessment tool. Assessment of these risk factors may help guide osteoporosis treatment choices by identifying patients in whom there is urgency to treat. Additional research is needed to validate the findings of this study and the accuracy of the risk assessment tool.
Source: Osteoporosis International - June 7, 2017 Category: Orthopaedics Source Type: research

Osteoporosis and ischemic cardiovascular disease
Publication date: Available online 9 November 2016 Source:Joint Bone Spine Author(s): Michel Laroche, Virginie Pécourneau, Hubert Blain, Véronique Breuil, Roland Chapurlat, Bernard Cortet, Bruno Sutter, Yannick Degboe Osteoporosis and cardiovascular disease were long viewed as independent of each other. However, numerous epidemiological studies, which are discussed in the first part of this review, have provided incontrovertible evidence of a link. Thus, the risk of coronary artery disease and stroke is higher in patients with a history of osteoporotic fracture or low bone mineral density than in non-osteoporotic patien...
Source: Joint Bone Spine - November 9, 2016 Category: Orthopaedics Source Type: research

Risk and prevention of fracture in patients with major medical illnesses: A mini ‐review
This article is protected by copyright. All rights reserved
Source: Journal of Bone and Mineral Research - November 3, 2016 Category: Orthopaedics Authors: Steven R. Cummings, Richard Eastell Tags: Review Source Type: research

Clinical characteristics and risk factors of postoperative pneumonia after hip fracture surgery: a prospective cohort study
ConclusionIntrinsic factors and major clinical interventions were all important risk factors of POP in patients after hip fracture surgery. Targeted preventive measures to mitigate the above risk factors may help in reducing the incidence of POP.
Source: Osteoporosis International - September 30, 2016 Category: Orthopaedics Source Type: research

Risk of hip fracture following stroke, a meta-analysis of 13 cohort studies
This study systematically reviews prospective and retrospective cohort studies evaluating the risk of hip fracture following stroke. Stroke survivors are at high risk of hip fracture and had a 1.5-fold increased risk compared to stroke-free men and women of the same age. Hip fracture often occurs in ageing and female stroke patients. We performed a meta-analysis to summarize evidence from prospective and retrospective cohort studies about the risk of hip fracture following stroke. We identified English and non-English publications in MEDLINE and EMBASE using stroke and fracture as keywords to 31 December 2015. The data of ...
Source: Osteoporosis International - August 12, 2016 Category: Orthopaedics Source Type: research

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