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Source: Frontiers in Neurology
Condition: Hemorrhagic Stroke

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Total 496 results found since Jan 2013.

Computational Approaches for Acute Traumatic Brain Injury Image Recognition
In recent years, there have been major advances in deep learning algorithms for image recognition in traumatic brain injury (TBI). Interest in this area has increased due to the potential for greater objectivity, reduced interpretation times and, ultimately, higher accuracy. Triage algorithms that can re-order radiological reading queues have been developed, using classification to prioritize exams with suspected critical findings. Localization models move a step further to capture more granular information such as the location and, in some cases, size and subtype, of intracranial hematomas that could aid in neurosurgical ...
Source: Frontiers in Neurology - March 9, 2022 Category: Neurology Source Type: research

Association Between Preonset Anti-hypertensive Treatment and Intracerebral Hemorrhage Mortality: A Cohort Study From CHEERY
ConclusionsPreonset anti-hypertensive therapy was associated with lower mortality of ICH, which somewhat depended on hematoma volume.
Source: Frontiers in Neurology - March 7, 2022 Category: Neurology Source Type: research

Epidemiology of Moyamoya Angiopathy in Eastern India
ConclusionMMA is an important etiological consideration in patients with stroke, especially in children. It can present with a myriad of transient neurological symptoms, frequently overlooked, leading to delayed diagnosis, and contributing to socio-economic burden. Indian MMA showed aberrations in its gender predisposition, age distribution, frequency of familial cases, disease manifestation, and type of stroke, in comparison to its Japanese and Caucasian counterparts pointing to the inter- and intra-continent differences of MMA phenotype. Future development of the Indian MMA national registry is of essence.
Source: Frontiers in Neurology - March 4, 2022 Category: Neurology Source Type: research

Sex-Differences in Oral Anticoagulant-Related Intracerebral Hemorrhage
ConclusionSignificant sex-differences were observed in age, risk factors, access to treatment, and DNRs while no significant differences were observed in comorbidity burden, stroke severity, or hematoma volume. Outcomes, such as adjusted mortality, ability to walk, and neurological deterioration, were comparable. This study supports the presence of sex-differences in risk factors and care but not in presentation and outcomes.
Source: Frontiers in Neurology - March 3, 2022 Category: Neurology Source Type: research

J147 Reduces tPA-Induced Brain Hemorrhage in Acute Experimental Stroke in Rats
ConclusionOur results demonstrate that J147 treatment alone exerts cerebral cytoprotective effects in a suture model of acute ischemic stroke, while in an embolic stroke model co-administration of J147 with tPA reduces delayed tPA-induced intracerebral hemorrhage and confers cerebroprotection. These findings suggest that J147-tPA combination therapy could be a promising approach to improving the treatment of ischemic stroke.
Source: Frontiers in Neurology - March 2, 2022 Category: Neurology Source Type: research

Editorial: Blood-Based Biomarkers in Acute Ischemic Stroke and Hemorrhagic Stroke
Source: Frontiers in Neurology - February 24, 2022 Category: Neurology Source Type: research

Minimally Invasive Surgery for Intracerebral and Intraventricular Hemorrhage
Spontaneous intracerebral hemorrhage (ICH), especially related to intraventricular hemorrhage (IVH), is the most devastating type of stroke and is associated with high mortality and morbidity. Optimal management of ICH remains one of the most controversial areas of neurosurgery and no effective treatment exists for ICH. Studies comparing conventional surgical interventions with optimal medical management failed to show significant benefit. Recent exploration of minimally invasive surgery for ICH and IVH including catheter- and mechanical-based approaches has shown great promise. Early phase clinical trials have confirmed t...
Source: Frontiers in Neurology - February 22, 2022 Category: Neurology Source Type: research

Effects of Repetitive Peripheral Sensory Stimulation in the Subacute and Chronic Phases After Stroke: Study Protocol for a Pilot Randomized Trial
DiscussionThe results of this study are relevant to inform future clinical trials to tailor RPSS to patients more likely to benefit from this intervention.Trial RegistrationNCT03956407.
Source: Frontiers in Neurology - February 16, 2022 Category: Neurology Source Type: research

New Remote Cerebral Microbleeds on T2*-Weighted Echo Planar MRI After Intravenous Thrombolysis for Acute Ischemic Stroke
ConclusionIn this study, new CMBs were found in nearly 30% of patients with AIS on the 7–9 days after rtPA treatment. Baseline CMBs correlated with a higher risk of new CMBs appearing after the rtPA treatment, independently of other factors. At the same time, in our sample, baseline CMBs did not correlate with an increased risk of hemorrhagic transformation. Since the associations between the CMBs load and cognitive impairment have already been proved, further studies are warranted to investigate possible associations between the thrombolytic treatment of patients with AIS, mainly those with baseline CMBs, and the risk o...
Source: Frontiers in Neurology - February 15, 2022 Category: Neurology Source Type: research

General Anesthesia vs. Local Anesthesia During Endovascular Treatment for Acute Large Vessel Occlusion: A Propensity Score-Matched Analysis
ConclusionIn the real-world setting, LA ± CS might provide more outcomes benefits than GA in patients with AIS-LVO during the procedure.
Source: Frontiers in Neurology - February 14, 2022 Category: Neurology Source Type: research

Triglyceride-Glucose Index and Intravenous Thrombolysis Outcomes for Acute Ischemic Stroke: A Multicenter Prospective –Cohort Study
ConclusionThis study supports the strong association between the increased TyG index and increased unfavorable functional outcomes at 90 days in patients with acute ischemic stroke treated with IVT. These findings were found to be robust in patients with moderate and high stroke severity.
Source: Frontiers in Neurology - February 14, 2022 Category: Neurology Source Type: research

A Novel Endovascular Therapy Strategy for Acute Ischemic Stroke Due to Intracranial Atherosclerosis-Related Large Vessel Occlusion: Stent-Pass-Aspiration-resCuE-Micowire-Angioplasty (SPACEMAN) Technique
ConclusionsThis study suggests that SPACEMAN exhibits a shorter operation revascularization time than the standard thrombectomy. Complications and prognosis were comparable between the two groups. The safety and efficacy of this novel technique need to be studied in larger patient series.
Source: Frontiers in Neurology - February 14, 2022 Category: Neurology Source Type: research

Pre-Existing Non-Disabling Encephalomalacia Confers Risk to Stroke Outcomes After Endovascular Treatment
ConclusionsA pre-existing non-disabling EM is common and safe in patients undergoing EVT. However, a contralateral EM and the large size of EM may predict an unfavorable outcome at 90 days, which should receive more attention before EVT.
Source: Frontiers in Neurology - February 11, 2022 Category: Neurology Source Type: research

Efficacy and Safety of Tirofiban in Clinical Patients With Acute Ischemic Stroke
ConclusionOur trial supports that tirofiban was safe and effective and might be a remedial treatment for patients with AIS who did not receive recanalization treatments.Clinical Trial Registrationhttp://www.chictr.org.cn/, identifier: ChiCTR2000031297.
Source: Frontiers in Neurology - February 8, 2022 Category: Neurology Source Type: research

Intracranial Arterial Calcification and Intracranial Atherosclerosis: Close but Different
ConclusionOur multimodal imaging-based comparison study on intracranial arteriosclerosis demonstrated that intimal IAC, compared with medial IAC, was more often accompanied by the luminal stenosis, larger plaque burden, eccentricity, and IPH, providing strong evidence for clinical evaluation on the mechanism, risk, and prognosis of ischemic stroke.
Source: Frontiers in Neurology - February 8, 2022 Category: Neurology Source Type: research