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Timing of Tracheostomy in Patients with Intracerebral Haemorrhage: A Propensity-Matched Analysis
CONCLUSION: We recommend ET for high-risk patients with ICH. Although ET cannot reduce in-hospital mortality or improve patient prognosis, it may help reduce hospital costs and ICU LOS as well as the use of antibiotics, sedatives and muscle relaxants.PMID:36125838 | DOI:10.2174/1567202619666220920122935
Source: Current Neurovascular Research - September 20, 2022 Category: Neurology Authors: Bo Luo Hua-Xuan Chen Xu-Dong Song Lin Wang Xue-Yun Deng Xiao-Ping Tang Source Type: research

Crosstalk between the angiotensin and endothelin-system in the cerebrovasculature.
Abstract Investigations have shown a multifactorial process as cause for the poor outcome after subarachnoid hemorrhage (SAH), including inflammation, early brain injury, cortical spreading depression, lack of cerebral autoregulation and the cerebral vasospasm (CVS) itself. Losartan may have a beneficial effect after SAH - preventing CVS, restoring cerebral autoregulation, reducing inflammation and early brain injury. Also some data is available for an AT1-receptor-upregulation and upregulated gene expression after subarachnoid hemorrhage, but the functional role of angiotensin on the cerebrovascular contractility...
Source: Current Neurovascular Research - August 30, 2013 Category: Neurology Authors: Konczalla J, Wanderer S, Mrosek J, Schuss P, Platz J, Güresir E, Seifert V, Vatter H Tags: Curr Neurovasc Res Source Type: research

Iron Overload is Associated with Perihematoma Edema Growth following Intracerebral Hemorrhage that May Contribute to in-Hospital Mortality and Long-Term Functional Outcome.
Abstract Iron overload may contribute to brain damage that involves delayed brain atrophy, edema, and neuronal cell death as well as unfavorable outcome following ischemic stroke and intracerebral hemorrhage (ICH).This prospective study wasperformed to determine the association of serum ferritin level, an iron storage protein, with perihematoma edema (PHE) growth as well as in-hospital mortality and long-term clinical outcome of patients with ICH.Data was collected prospectively from patients with ICH between February 2011 and April 2012. Demographicand clinical datawere recorded and serum ferritin was measured on...
Source: Current Neurovascular Research - May 30, 2014 Category: Neurology Authors: Bakhshayesh B, Hosseininezhad M, Nazanin S, Saadat SN, Ansar MM, Ramezani H, Saadat SM Tags: Curr Neurovasc Res Source Type: research

Cyclooxygenase-2 and Prostaglandin E2 are Associated with Middle Cerebral Artery Occlusion and Hemorrhage in Patients with Moyamoya Disease.
In this study, tiny pieces of middle cerebral artery (MCA) and superficial temporal artery (STA) were surgically harvested from 18 adult MMD patients and 5 surgical control patients. The expression levels of COX-2 and microsomal prostaglandin E2 synthase-1 (mPGES-1) in the vascular walls were immunohistochemically detected. With additional 10 healthy controls, the plasma levels of PGE2 were also measured by enzyme-linked immunosorbent assay (ELISA). Obvious intimal thickening was observed in both STA and MCA of MMD patients, but not in the controls. However, the MCA had a thicker intima than the STA (P < 0.01). Although...
Source: Current Neurovascular Research - October 27, 2015 Category: Neurology Authors: Zhang J, Xiong Z, Wang S, He Y, Sun S, Wu X, Wang L, Zhang H, You C, Wang Y, Chen J Tags: Curr Neurovasc Res Source Type: research

Prognostic significance of serum magnesium in acute intracerebral hemorrhage patients.
CONCLUSIONS: Elevated admission serum magnesium level is associated with lower odds of mortality but not poor functional outcome at 3 months in patients with acute ICH. PMID: 30977445 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - April 11, 2019 Category: Neurology Authors: Han X, You S, Huang Z, Han Q, Zhong C, Xu J, Shi R, Chen D, Xiao G, Zhang Y, Cao Y, Liu CF Tags: Curr Neurovasc Res Source Type: research

Posterior internal frontal artery vascularization of the precentral gyrus responsible for proximal arm movement: insight from a case of coil migration.
CONCLUSION: This case adds to our understanding of the vascularization of the precentral gyrus by distal ACA branches, in particular the PIFA. PMID: 32807055 [PubMed - as supplied by publisher]
Source: Current Neurovascular Research - August 16, 2020 Category: Neurology Authors: Bergeron D, Westwick HJ, Obaid S, Bojanowski MW Tags: Curr Neurovasc Res Source Type: research

U-Shaped Association Between Serum Uric Acid and Hemorrhagic Transformation After Thrombolysis
CONCLUSION: The data show the U-shaped relationship between serum UA levels and the risk of HT and sICH after intravenous thrombolysis.PMID:35796447 | DOI:10.2174/1567202619666220707093427
Source: Current Neurovascular Research - July 7, 2022 Category: Neurology Authors: Zicheng Cheng Zhenxiang Zhan Yaming Fu WenYuan Zhang Lingfan Xia Tong Xu Hongfang Chen Zhao Han Source Type: research

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