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Condition: Hemorrhagic Stroke
Countries: Japan Health

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Total 300 results found since Jan 2013.

Interference of New Antiseizure Agents with Hospital Transfer of Stroke Patients in Japan: A Retrospective Cohort Study
Biol Pharm Bull. 2023;46(3):440-445. doi: 10.1248/bpb.b22-00787.ABSTRACTPatients in Japan often have difficulty in screening and selecting chronic-care and rehabilitation hospitals for transfer because of the high cost and unavailability of new antiseizure medications, such as perampanel and lacosamide. To investigate whether the requirement for perampanel and lacosamide interfered with patients' hospital transfer by comparing the number of days required for hospital transfer. Data were obtained from patients 1) who were diagnosed with intracerebral hemorrhage or cerebral infarction, 2) who were treated with antiseizure me...
Source: Biological and Pharmaceutical Bulletin - March 1, 2023 Category: Drugs & Pharmacology Authors: Satoru Matsunuma Shigeki Sunaga Koichi Yoshimoto Hiroyuki Jimbo Source Type: research

Rare RNF213 variant in adolescent with moyamoya disease
CONCLUSION: To our knowledge, the p.(Arg406262Gln) variant has been reported in three Japanese moyamoya disease patients and one European. Therefore, our patient was the second European moyamoya disease patient with this variant identified.PMID:36843178 | DOI:10.33588/rn.7605.2021392
Source: Revista de Neurologia - February 27, 2023 Category: Neurology Authors: I Cardoso M Pinto A Ara újo M Vila-Real Source Type: research

In-vitro antioxidant, lipoxygenase inhibitory, and in-vivo muscle relaxant potential of the extract and constituent isolated from Diospyros kaki (Japanese Persimmon)
This study excellently rationalizes the traditional usage of D. kaki in curing various diseases. Furthermore, the docking results indicate, that the isolated compound fits well into the active site of the lipoxygenase, and makes strong interactions with the target protein.PMID:36895410 | PMC:PMC9989937 | DOI:10.1016/j.heliyon.2023.e13816
Source: Atherosclerosis - March 10, 2023 Category: Cardiology Authors: Adil Mujawah Abdur Rauf Sami Bawazeer Abdul Wadood Hassan A Hemeg Saud Bawazeer Source Type: research

Type I Thyroplasty Is Safe in Patients Undergoing Antithrombotic Therapy
Conclusion: Type I thyroplasty with careful pre- and postoperative management is safe in patients undergoing antithrombotic therapy.ORL
Source: ORL - April 26, 2023 Category: ENT & OMF Source Type: research

Roche enters partnership with Alnylam to co-develop and co-commercialise RNAi therapeutic zilebesiran to treat hypertension in patients with high cardiovascular risk
Partnership combines Roche ’s proven track record of successfully developing and launching innovative medicines worldwide withAlnylam ’s leadership in RNAi therapeuticsZilebesiran, a Phase 2 RNAi therapeutic, has best-in-disease potential for patients with hypertension at high risk of cardiovascular morbidity and mortality, by robustly and durably lowering blood pressureHypertension, the leading cause of cardiovascular disease, affects more than 1.2 billion adults worldwide. While several therapies exist, a significant unmet need, especially for high risk patients, remains.1Basel, 24 July 2023 - Roche (SIX: RO, ROG; OT...
Source: Roche Media News - July 24, 2023 Category: Pharmaceuticals Source Type: news

E-040 Natural history of vertebrobasilar dolichoectasia - multinational study
ConclusionThis study verifies malignancy of VBADA and encourage invasive treatment in early phase of disease progression based on radiological characteristics, age and sex of the patients when treatment option is seen suitable.Disclosures B. Rezai Jahromi: None. N. Ota: None. V. Srinivasan: None. S. Henriksson: None. R. Dashti: None. C. Schwartz: None. J. Jääskeläinen: None. A. Lindgren: None. T. Koivisto: None. B. Jahromi: None. K. Noda: None. M. Potts: None. R. Tanikawa: None. Y. Kalani: None. P. Vajkoczy: None. R. Spetzler: None. F. Göhre: None. J. Hernesniemi: None. M. Lawton: None. M. N...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Rezai Jahromi, B., Ota, N., Srinivasan, V., Henriksson, S., Dashti, R., Schwartz, C., Jääskeläinen, J., Lindgren, A., Koivisto, T., Jahromi, B., Noda, K., Potts, M., Tanikawa, R., Kalani, Y., Vajkoczy, P., Spetzler, R., Göh Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

Spontaneous middle cerebral artery dissection: a series of six cases and literature review
AbstractMiddle cerebral artery (MCA) dissection is rare, and various clinical presentations, including hemorrhage, ischemia, or comorbidities, and the changes in imaging findings over time hinder treatment decisions. The European Stroke Organization guidelines exclude MCA dissection. Few cases have been reported with no review of the relevant literature. Therefore, we reviewed the relevant literature and our own experience with non-traumatic MCA dissection cases to determine appropriate treatment strategies. At our institution and affiliated institutions, we encountered six cases of MCA dissection —five with infarction a...
Source: Neurosurgical Review - September 7, 2023 Category: Neurosurgery Source Type: research

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