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Condition: Hemorrhagic Stroke
Countries: Japan Health

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Total 300 results found since Jan 2013.

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

Roche and Alnylam report positive topline results from Phase 2 study KARDIA-1 of zilebesiran, an investigational RNAi therapeutic in development to treat hypertension in patients at high risk of cardiovascular disease
Zilebesiran met primary endpoint demonstrating greater than 15 mmHg reduction of systolic blood pressure at three months of treatment compared to placeboStudy met key secondary endpoints showing consistent and sustained reductions of systolic blood pressure at six monthsZilebesiran demonstrated an encouraging safety and tolerability profile in adult patients with mild-to-moderate hypertensionFull study results to be presented at an upcoming scientific conferenceBasel, 7 September 2023 - Roche (SIX: RO, ROG; OTCQX: RHHBY) and Alnylam announced today that the Phase 2 study KARDIA-1 of zilebesiran, an investigational RNAi the...
Source: Roche Media News - September 7, 2023 Category: Pharmaceuticals Source Type: news

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

Efficacy of Endovascular Revascularization in Elderly Patients with Acute Large Vessel Occlusion: Analysis from the RESCUE-Japan Retrospective Nationwide Survey
Conclusions: The elderly population could achieve favorable outcomes comparable to the nonelderly population, especially when they achieve any recanalization by EVT. Elderly patients should not be excluded from recanalization therapy with EVT because of age.
Source: Journal of Stroke and Cerebrovascular Diseases - December 30, 2011 Category: Neurology Authors: Yusuke Egashira, Shinichi Yoshimura, Nobuyuki Sakai, Naoya Kuwayama, Recovery by Endovascular Salvage for Cerebral Ultra-acute Embolism (RESCUE)-Japan Retrospective Survey Group Tags: Original Articles Source Type: research

Teaching NeuroImages: Artery of Percheron aneurysm masquerading as ICH spot sign
A 50-year-old Japanese woman presented with left thalamic intracerebral hemorrhage (ICH). CT angiography demonstrated an ICH spot sign and intracranial vasculopathy consistent with Moyamoya disease (figure 1). Conventional angiography demonstrated that the spot sign was actually a pseudoaneurysm arising from the artery of Percheron (figure 2). Intracranial aneurysms may complicate Moyamoya disease and occur at the circle of Willis, distal peripheral arteries, or Moyamoya vessels at a ratio of 3:1:1.1 Aneurysms in thalamo-perforating arteries are rare2 and an artery of Percheron aneurysm in Moyamoya disease has not been rep...
Source: Neurology - August 7, 2017 Category: Neurology Authors: Moughamian, A. J., Morshed, R. A., Colorado, R. A., Liner, Z., Cooke, D., Hemphill, J. C. Tags: All Cerebrovascular disease/Stroke, Intracerebral hemorrhage RESIDENT AND FELLOW SECTION Source Type: research

Efficacy and safety of rivaroxaban in extreme elderly patients with atrial fibrillation: Analysis of the Shikoku Rivaroxaban Registry Trial (SRRT).
CONCLUSION: These results suggest that rivaroxaban is effective and safe in extreme elderly patients with atrial fibrillation. PMID: 28969968 [PubMed - as supplied by publisher]
Source: Journal of Cardiology - September 29, 2017 Category: Cardiology Authors: Bando S, Nishikado A, Hiura N, Ikeda S, Kakutani A, Yamamoto K, Kaname N, Fukatani M, Takagi Y, Yukiiri K, Fukuda Y, Nakaya Y Tags: J Cardiol Source Type: research

Dual energy computed tomography for the head
AbstractDual energy CT (DECT) is a promising technology that provides better diagnostic accuracy in several brain diseases. DECT can generate various types of CT images from a single acquisition data set at high kV and low kV based on material decomposition algorithms. The two-material decomposition algorithm can separate bone/calcification from iodine accurately. The three-material decomposition algorithm can generate a virtual non-contrast image, which helps to identify conditions such as brain hemorrhage. A virtual monochromatic image has the potential to eliminate metal artifacts by reducing beam-hardening effects. DEC...
Source: Japanese Journal of Radiology - November 9, 2017 Category: Radiology Source Type: research

Effect of actual age on outcome at discharge in patients by surgical clipping and endovascular coiling for ruptured cerebral aneurysm in Japan
In conclusion, the cutoff age for poor m RS score>  2 was 3 to 9 years older for EC than for SC. Actual age was one of the indications for elderly patients to achieve the optimum outcome; however, the treatment indication should be carefully considered based on the condition in each country.
Source: Neurosurgical Review - January 15, 2018 Category: Neurosurgery Source Type: research