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Life-Space Mobility: Normative Values from a National Cohort of U.S. Older Adults
CONCLUSIONS: We report US national norms for LSA among community-dwelling Black and White older adults. These norms can serve as a reference tool for determining if clinical and research samples have greater or lesser life-space mobility than typical older adults in the US for their age and sex.PMID:37480583 | DOI:10.1093/gerona/glad176
Source: Biol Sci Space - July 22, 2023 Category: Science Authors: Alexander X Lo Virginia G Wadley Cynthia J Brown D Leann Long Michael Crowe Virginia J Howard Richard E Kennedy Source Type: research

How John Fetterman Came Out of the Darkness
When he looks back on the past year—a year in which he nearly died, became a U.S. Senator, and nearly died again—it is the debate that John Fetterman identifies as the ­breaking point. “The debate lit the mitch,” he says, then shakes his head in frustration and tries again. The right word is there in his brain, but he struggles to get it out. “Excuse me, that should be lit the mitch—” He stops and tries again. “Lit the match,” he says finally. Oct. 25, 2022: the date is lodged in his mind. “I knew I had to do it,” he tells me. “I knew that the vote...
Source: TIME: Health - July 20, 2023 Category: Consumer Health News Authors: Molly Ball Tags: Uncategorized Congress Cover Story Exclusive feature uspoliticspolicy Source Type: news

Astrocytes in Post-Stroke Depression: Roles in Inflammation, Neurotransmission, and Neurotrophin Signaling
Cell Mol Neurobiol. 2023 Jul 20. doi: 10.1007/s10571-023-01386-w. Online ahead of print.ABSTRACTPost-stroke depression (PSD) is a frequent and disabling complication of stroke that affects up to one-third of stroke survivors. The pathophysiology of PSD involves multiple mechanisms, including neurochemical, neuroinflammatory, neurotrophic, and neuroplastic changes. Astrocytes are a type of glial cell that is plentiful and adaptable in the central nervous system. They play key roles in various mechanisms by modulating neurotransmission, inflammation, neurogenesis, and synaptic plasticity. This review summarizes the latest ev...
Source: Cellular and Molecular Neurobiology - July 20, 2023 Category: Cytology Authors: Dongqing Jing Xiaoli Hou Xiao Guo Xin Zhao Kexin Zhang Jingwen Zhang Chengxia Kan Fang Han Junling Liu Xiaodong Sun Source Type: research

Long-term effectiveness, outcomes and complications of bariatric surgery
World J Clin Cases. 2023 Jul 6;11(19):4504-4512. doi: 10.12998/wjcc.v11.i19.4504.ABSTRACTDietary imbalance and overeating can lead to an increasingly widespread disease - obesity. Aesthetic considerations aside, obesity is defined as an excess of adipose tissue that can lead to serious health problems and can predispose to a number of pathological changes and clinical diseases, including diabetes; hypertension; atherosclerosis; coronary artery disease and stroke; obstructive sleep apnea; depression; weight-related arthropathies and endometrial and breast cancer. A body weight 20% above ideal for age, gender and height is a...
Source: Clinical Breast Cancer - July 20, 2023 Category: Cancer & Oncology Authors: Milena Gulinac Dimitrina Georgieva Miteva Monika Peshevska-Sekulovska Ivan P Novakov Svetozar Antovic Milena Peruhova Violeta Snegarova Plamena Kabakchieva Yavor Assyov Georgi Vasilev Metodija Sekulovski Snezhina Lazova Latchezar Tomov Tsvetelina Velikova Source Type: research