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Prevalence and associated relating factors in patients with hereditary retinal dystrophy: a nationwide population-based study in Taiwan
Conclusions 74% of the diagnosed HRD are retinitis pigmentosa. Population-based data suggested an increased incidence of cataract in younger patients, whereas older HRD patients are more susceptible to develop CME. Further work is needed to elucidate the mechanism between these ophthalmological disorders and HRD.
Source: BMJ Open - April 8, 2022 Category: General Medicine Authors: Woon, P. Y., Chien, J.-Y., Wang, J.-H., Chou, Y.-Y., Lin, M.-C., Huang, S.-P. Tags: Open access, Ophthalmology Source Type: research

Amoxicillin/clavulanic acid-associated severe neutropenia
A 72-year-old man presented with an abnormal blood count and was admitted. His history included hypertension and hyperlipidaemia with an old myocardial infarction and mild stroke; liver cirrhosis due to non-alcoholic steatohepatitis (NASH) with hypersplenism and oesophageal varices but no ascites, oedema or bleeding; and benign prostatic hypertrophy. His medications (unchanged for years) included furosemide, spironolactone, bisoprolol, rosuvastatin, alfuzosin and omeprazole. Two weeks prior, he was discharged from our department after left leg cellulitis and Streptococcus pyogenes bacteraemia responsive to parenteral clind...
Source: Postgraduate Medical Journal - March 22, 2022 Category: General Medicine Authors: Schattner, A., Dubin, I. Tags: Adverse drug reactions Source Type: research

Multimorbidity patterns and association with mortality in 0.5 million Chinese adults
CONCLUSION: Cardiometabolic multimorbidity and respiratory multimorbidity posed the highest threat on mortality risk and deserved particular attention in Chinese adults.PMID:35191418 | DOI:10.1097/CM9.0000000000001985
Source: Chinese Medical Journal - February 22, 2022 Category: General Medicine Authors: Junning Fan Zhijia Sun Canqing Yu Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Dianjianyi Sun Yuanjie Pang Jun Zhang Simon Gilbert Daniel Avery Junshi Chen Zhengming Chen Jun Lyu Liming Li China Kadoorie Biobank Collaborative Group Source Type: research

Chronic diseases and socioeconomic inequalities in quality of life among Brazilian adults: findings from a population-based study in Southern Brazil
ConclusionsThe occurrence of long-lasting chronic diseases is associated with inequalities in QoL (physical and psychological domains), with stronger adverse effects among older adults, blacks and individuals with lower income or educational levels.
Source: The European Journal of Public Health - December 25, 2017 Category: General Medicine Source Type: research

Cirrhosis Could Raise Stroke Risk
MONDAY, June 5, 2017 -- Cirrhosis -- a stiffening of liver tissue that ' s often tied to excessive drinking of alcohol -- may also raise an older person ' s odds for a stroke, a new study suggests. " In a nationally representative sample of elderly...
Source: Drugs.com - Daily MedNews - June 5, 2017 Category: General Medicine Source Type: news

Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980 –2015: a systematic analysis for the Global Burden of Disease Study 2015
Publication date: 8–14 October 2016 Source:The Lancet, Volume 388, Issue 10053 Author(s): GBD 2015 Mortality and Causes of Death CollaboratorsHaidongWangMohsenNaghaviChristineAllenRyan MBarberZulfiqar ABhuttaAustinCarterDaniel CCaseyFiona JCharlsonAlan ZianChenMatthew MCoatesMeganCoggeshallLalitDandonaDaniel JDickerHolly EErskineAlize JFerrariChristinaFitzmauriceKyleForemanMohammad HForouzanfarMaya SFraserNancyFullmanPeter WGethingEllen MGoldbergNicholasGraetzJuanita AHaagsmaSimon IHayChantalHuynhCatherine OJohnsonNicholas JKassebaumYohannesKinfuXie RachelKulikoffMichaelKutzHmwe HKyuHeidi JLarsonJanniLeungXiaofengLiangS...
Source: The Lancet - October 6, 2016 Category: Journals (General) Source Type: research

Point-of-Care Echocardiography Improves Assessment of Volume Status in Cirrhosis and Hepatorenal Syndrome.
Abstract The management of patients with cirrhosis along with acute kidney injury is complex and depends in large part on accurate assessment of intravascular volume status. Assessment of intravascular volume status by point-of-care echocardiography often relies solely on inferior vena cava size and variability evaluation; however, this parameter should be interpretated with an understanding of right ventricular function integrated with stroke volume and flow. Attempts to optimize intra-abdominal hemodynamics favorably are clearly problematic when physical examination findings or rudimentary assessments of central...
Source: The American Journal of the Medical Sciences - April 30, 2016 Category: Journals (General) Authors: Huggins JT, Doelken P, Walters C, Rockey DC Tags: Am J Med Sci Source Type: research

Cardiac manifestations in alcoholic liver disease
Alcoholic liver disease is the most prevalent cause of progressive liver disease in Europe. Alcoholic cirrhosis occurs in 8%–20% of cases of alcoholic liver disease. It has significant influence on cardiovascular system and haemodynamics through increased heart rate, cardiac output, decreased systemic vascular resistance, arterial pressure and plasma volume expansion. Cirrhotic cardiomyopathy is characterised by systolic and diastolic dysfunction and electrophysiological abnormalities, if no other underlying cardiac disease is present. It is often unmasked only during pharmacological or physiological stress, when com...
Source: Postgraduate Medical Journal - March 21, 2016 Category: Journals (General) Authors: Milic, S., Lulic, D., Stimac, D., Ruzic, A., Zaputovic, L. Tags: Reviews Source Type: research

Point-of-Care Echocardiography Improves Assessment of Volume Status in Cirrhosis and Hepatorenal Syndrome.
Abstract The management of cirrhotic patients with acute kidney injury is complex and depends in large part on accurate assessment of intravascular volume status. Assessments of intravascular volume status by point-of-care echocardiography often rely solely on inferior vena cava size/variability evaluation; however, this parameter should be intrepretated with an understanding of right ventricular function integrated with stroke volume/flow. Attempts to optimize intra-abdominal hemodynamics favorably are clearly problematic when physical examination findings or rudimentary assessments of central venous pressure or ...
Source: The American Journal of the Medical Sciences - April 17, 2015 Category: Journals (General) Authors: Huggins JT, Doelken P, Walters C, Rockey DC Tags: Am J Med Sci Source Type: research

FloTrac® Monitoring System: What Are Its Uses in Critically Ill Medical Patients?
Abstract: The FloTrac®/Vigileo device uses arterial pressure waveform analysis to calculate stroke volume and cardiac output; it does not require calibration against an independent measurement of cardiac output. Consequently, it provides a method to determine hemodynamic status, changes in the clinical course and responses to therapeutic interventions in patients who have arterial catheters in place. These devices perform relatively well in stable patients undergoing surgery and having an acceptable percentage error in differences between the FloTrac® device and invasive monitoring using pulmonary catheters. However, in ...
Source: The American Journal of the Medical Sciences - March 31, 2015 Category: Journals (General) Tags: Review Article Source Type: research

FloTrac® Monitoring System: What Are Its Uses in Critically Ill Medical Patients?
Abstract : The FloTrac®/Vigileo device uses arterial pressure waveform analysis to calculate stroke volume and cardiac output; it does not require calibration against an independent measurement of cardiac output. Consequently, it provides a method to determine hemodynamic status, changes in the clinical course and responses to therapeutic interventions in patients who have arterial catheters in place. These devices perform relatively well in stable patients undergoing surgery and having an acceptable percentage error in differences between the FloTrac® device and invasive monitoring using pulmonary catheters. Ho...
Source: The American Journal of the Medical Sciences - January 12, 2015 Category: Journals (General) Authors: Argueta E, Berdine G, Pena C, Nugent KM Tags: Am J Med Sci Source Type: research