• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Risk factors for dementia in older intensive care unit (ICU) survivors
DISCUSSION: Future studies will need to examine whether interventions targeting post-ICU stroke and depression can lower dementia incidence in ICU survivors.HIGHLIGHTS: Risk factors for post-intensive care unit (ICU) dementia were distinct from those of Alzheimer's disease. Cardiovascular risk factors were not associated with dementia in older ICU survivors. Post-ICU stroke was associated with a higher risk of dementia in older ICU survivors. Post-ICU depression was associated with a higher risk of dementia in older ICU survivors.PMID:37589315 | DOI:10.1002/alz.13423
Source: The Journal of Alzheimers Association - August 17, 2023 Category: Psychiatry Authors: Sophia Wang Anthony J Perkins Rosalyn Chi Brandon A Yates Sikandar H Khan Sujuan Gao Malaz Boustani Babar A Khan Source Type: research

Brain health and mental health: Common vascular risk factors and practical implications
Alzheimers Dement. 2023 May 22. doi: 10.1002/alz.13153. Online ahead of print.ABSTRACTThe pandemic dramatized the close links among cognitive, mental, and social health; a change in one reflects others. This realization offers the opportunity to bridge the artificial separation of brain and mental health, as brain disorders have behavioral consequences and behavioral disorders affect the brain. The leading causes of mortality and disability, namely stroke, heart disease, and dementia, share the same risk and protective factors. It is emerging that bipolar disorders, obsessive compulsive disorders, and some depressions shar...
Source: The Journal of Alzheimers Association - May 22, 2023 Category: Psychiatry Authors: Vladimir Hachinski Ennapadam Krishnamoorthy Levent Kuey Laurence J Kirmayer Source Type: research

Prevalent stroke, age of its onset, and post-stroke lifestyle in relation to dementia: A prospective cohort study
DISCUSSION: Stroke onset in earlier life stage predicted a higher risk for dementia, but a favorable post-stroke lifestyle may protect against dementia.PMID:37157186 | DOI:10.1002/alz.13122
Source: The Journal of Alzheimers Association - May 9, 2023 Category: Psychiatry Authors: Wansi Zhong Hui Chen Xiaoxian Gong Lusha Tong Xin Xu Geng Zong Changzheng Yuan Min Lou Source Type: research

2023 Alzheimer's disease facts and figures
This article describes the public health impact of Alzheimer's disease, including prevalence and incidence, mortality and morbidity, use and costs of care, and the overall impact on family caregivers, the dementia workforce and society. The Special Report examines the patient journey from awareness of cognitive changes to potential treatment with drugs that change the underlying biology of Alzheimer's. An estimated 6.7 million Americans age 65 and older are living with Alzheimer's dementia today. This number could grow to 13.8 million by 2060 barring the development of medical breakthroughs to prevent, slow or cure AD. Off...
Source: The Journal of Alzheimers Association - March 15, 2023 Category: Psychiatry Source Type: research

Cognitive trajectories and incident dementia after a cardiovascular event in older adults
DISCUSSION: Findings highlight the importance of monitoring cognition after a CVD event.PMID:36856152 | DOI:10.1002/alz.13006
Source: The Journal of Alzheimers Association - March 1, 2023 Category: Psychiatry Authors: Swarna Vishwanath Ingrid Hopper Rory Wolfe Galina Polekhina Christopher M Reid Andrew M Tonkin Anne M Murray Raj C Shah Elsdon Storey Robyn L Woods John McNeil Suzanne G Orchard Mark R Nelson Claire J Steves Joanne Ryan Source Type: research

High cholesterol levels change the association of biomarkers of neurodegenerative diseases with dementia risk: Findings from a population-based cohort
This study assessed whether in a population with comorbidity of neurodegenerative and cerebrovascular disease (mixed pathology) the association of glial fibrillary acidic protein (GFAP), neurofilament light chain (NfL), and phosphorylated tau181 (p-tau181) with dementia risk varied depending on levels of total cholesterol and apolipoprotein E (APOE) ε4 genotype.METHODS: Plasma biomarkers were measured using Simoa technology in 768 participants of a nested case-control study embedded within an ongoing population-based cohort. Logistic and spline regression models, and receiver operating characteristic curves were calculate...
Source: The Journal of Alzheimers Association - January 13, 2023 Category: Psychiatry Authors: Laura Perna Ute Mons Hannah Stocker L éon Beyer Konrad Beyreuther Kira Trares Bernd Holleczek Ben Sch öttker Robert Perneczky Klaus Gerwert Hermann Brenner Source Type: research

Prevalence of neuropsychiatric conditions and cognitive impairment in two parallel, aging study cohorts from rural and urban India
DISCUSSION: Longitudinal assessment of these neuropsychiatric conditions, with parallel cognitive monitoring, will help identify their causal relationship with dementia.PMID:36573020 | DOI:10.1002/alz.12741
Source: The Journal of Alzheimers Association - December 27, 2022 Category: Psychiatry Authors: Jonas S Sundarakumar Abhishek L Menesgere Shubham Jain Shafeeq K S Hameed SANSCOG & TLSA Study Teams Vijayalakshmi Ravindranath Source Type: research

Multimorbidity burden and developmental trajectory in relation to later-life dementia: A prospective study
CONCLUSIONS: Both multimorbidity burden and its developmental trajectory were prospectively associated with risk of dementia.PMID:36427050 | DOI:10.1002/alz.12840
Source: The Journal of Alzheimers Association - November 25, 2022 Category: Psychiatry Authors: Hui Chen Yaguan Zhou Liyan Huang Xiaolin Xu Changzheng Yuan Source Type: research

We are preventing some dementias now-But how? The Potamkin lecture
Alzheimers Dement. 2022 Sep 22. doi: 10.1002/alz.12770. Online ahead of print.ABSTRACTMost dementias are untreatable and their prevalence is increasing around the world. However, the incidence of dementia is declining in some countries. We need to find out urgently why and how and apply the lessons promptly and widely. Given the multiplicity and variability of environmental, socioeconomic, and individual risk and protective factors, the approach needs to be comprehensive, customized to work in a particular setting, and cost effective, to justify the needed funding. Stroke, heart disease, and dementia share the same major p...
Source: The Journal of Alzheimers Association - September 22, 2022 Category: Psychiatry Authors: Vladimir Hachinski Dementia Prevention/Brain Health Initiative Source Type: research

Pages: 1  2  3  4  5