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Global, regional, and national trends of dementia incidence and risk factors, 1990-2019: A Global Burden of Disease study
CONCLUSION: The declining incidence of dementia in some countries, despite growing prevalence, is encouraging and urges further investigation.PMID:36044376 | DOI:10.1002/alz.12764
Source: The Journal of Alzheimers Association - August 31, 2022 Category: Psychiatry Authors: Abolfazl Avan Vladimir Hachinski Source Type: research

Cardiometabolic multimorbidity accelerates cognitive decline and dementia progression
CONCLUSIONS: CMD multimorbidity accelerates cognitive decline and increases the risk of both CIND and its conversion to dementia.HIGHLIGHTS: We explored the combined impact of cardiometabolic diseases (CMDs) on cognition. An increasing number of CMDs dose-dependently accelerated cognitive decline. CMD multimorbidity increased the risk of both cognitive impairment and dementia. Co-morbid CMDs could be ideal targets for interventions to protect cognitive health.PMID:35708183 | DOI:10.1002/alz.12708
Source: The Journal of Alzheimers Association - June 16, 2022 Category: Psychiatry Authors: Abigail Dove Anna Marseglia Ying Shang Giulia Grande Davide Liborio Vetrano Erika J Laukka Laura Fratiglioni Weili Xu Source Type: research

White matter hyperintensities and longitudinal cognitive decline in cognitively normal populations and across diagnostic categories: A meta-analysis, systematic review, and recommendations for future study harmonization
DISCUSSION: Recommendations and future directions for study of WMHs are provided to improve cross-study comparison and translation of research into consistent clinical interpretation.PMID:35319162 | DOI:10.1002/alz.12642
Source: The Journal of Alzheimers Association - March 23, 2022 Category: Psychiatry Authors: Austyn D Roseborough Lorenzo Saad Maren Goodman Lauren E Cipriano Vladimir C Hachinski Shawn N Whitehead Source Type: research

2022 Alzheimer's disease facts and figures
This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, use and costs of care, and the overall impact on family caregivers, the dementia workforce and society. The Special Report discusses consumers' and primary care physicians' perspectives on awareness, diagnosis and treatment of mild cognitive impairment (MCI), including MCI due to Alzheimer's disease. An estimated 6.5 million Americans age 65 and older are living with Alzheimer's dementia today. This number could grow to 13.8 million by 2060 barring the development of medical breakthrough...
Source: The Journal of Alzheimers Association - March 15, 2022 Category: Psychiatry Source Type: research

The comprehensive, customized, cost-effective approach (CCCAP) to prevention of dementia
This article proposes one way. It requires that the approach be (1) comprehensive, taking into account all relevant environmental, socioeconomic, and individual risk and protective factors; (2) customized, because contributing factors vary by region and among individuals; and (3) cost effective, implemented in actionable units. Savings of scale could occur by preventing stroke, heart disease, and dementia together. They share the same risk factors and pose risks for each other. Brain health could be the unifying, motivating, and actionable key to health, productivity, and well-being.PMID:35103397 | DOI:10.1002/alz.12586
Source: The Journal of Alzheimers Association - February 1, 2022 Category: Psychiatry Authors: Vladimir Hachinski Dementia Prevention Initiative Source Type: research

Tube feeding in patients with dementia is associated with a longer palliative care unit stay
CONCLUSION: The present study showed that, in patients with an established diagnosis of dementia, TF is common and independently associated with a longer length of PCU stay. Nevertheless, the study was underpowered and the results deserve confirmation in larger studies.PMID:34971282 | DOI:10.1002/alz.052919
Source: The Journal of Alzheimers Association - December 31, 2021 Category: Psychiatry Authors: Hilal Zengin Ilker Tasci Source Type: research

Brain health: Key to health, productivity, and well-being
Alzheimers Dement. 2021 Sep 27. doi: 10.1002/alz.12478. Online ahead of print.ABSTRACTBrain health is essential for physical and mental health, social well-being, productivity, and creativity. Current neurological research focuses mainly on treating a diseased brain and preventing further deterioration rather than on developing and maintaining brain health. The pandemic has forced a shift toward virtual working environments that accelerated opportunities for transdisciplinary collaboration for fostering brain health among neurologists, psychiatrists, psychologists, neuro and socio-behavioral scientists, scholars in arts an...
Source: The Journal of Alzheimers Association - September 27, 2021 Category: Psychiatry Authors: Abolfazl Avan Vladimir Hachinski Brain Health Learn and Act Group Source Type: research

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