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Specialty: Hematology
Condition: Bleeding
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Total 643 results found since Jan 2013.
Real-world comparison of direct-acting oral anticoagulants and vitamin K antagonists in chronic kidney disease: a systematic review and meta-analysis
Conclusion: DOACs are associated with only a modest reduction in stroke or systemic embolism, major bleeding, and mortality when compared to VKA in CKD patients. Reduction in mortality and major bleeding with DOAC may only be seen in moderate-to-severe CKD patients.PMID:33949923 | DOI:10.1080/17474086.2021.1920012
Source: Expert Review of Hematology - May 5, 2021 Category: Hematology Authors: Rongfang Xu Fan Wu Jiarong Lan Peixin Duan Source Type: research
Safety and Efficacy of Different Antithrombotic Strategies After Transcatheter Aortic Valve Implantation: A Network Meta-Analysis
CONCLUSIONS: The present network meta-analysis supports after TAVI the use of SAPT in patients without indication for OAC and OAC alone in those needing long-term anticoagulation.PMID:33930901 | DOI:10.1055/a-1496-8114
Source: Thrombosis and Haemostasis - April 30, 2021 Category: Hematology Authors: Eliano Pio Navarese Leonardo Grisafi Enrico Spinoni Marco Giovanni Mennuni Andrea Rognoni Jakub Ratajczak Przemys ław Podhajski Endrin Koni Jacek Kubica Giuseppe Patti Source Type: research
Thrombocytopenia with acute ischemic stroke and bleeding in a patient newly vaccinated with an adenoviral vector-based COVID-19 vaccine
We describe the first Danish case of presumed inflammatory and thrombotic response to vaccination with an adenoviral (ChAdOx1) vector based COVID-19 vaccine (AZD1222). The case describes a 60-year old woman, who was admitted with intractable abdominal pain seven days after receiving the vaccine. Computer Tomography (CT) of the abdomen revealed bilateral adrenal hemorrhages. On the following day she developed a massive right sided ischemic stroke and Magnetic Resonance Imaging (MRI) angiography showed occlusion of the right internal carotid artery. The ischemic area was deemed too large to offer reperfusion therapy. During ...
Source: Thrombosis and Haemostasis - April 20, 2021 Category: Hematology Authors: Rolf Ankerlund Blauenfeldt S øren Risom Kristensen Siw Leiknes Ernstsen Claudia Christina Hilt Kristensen Claus Ziegler Simonsen Anne-Mette Hvas Source Type: research
Gender differences with short-term vs 12 months dual antiplatelet therapy in patients with acute coronary syndrome treated with the COMBO dual therapy stent: 2-years follow-up results of the REDUCE trial
ConclusionsThe present study shows that among ACS patients randomized in the REDUCE trial, a 3 months DAPT strategy offers comparable results as compared to a standard 12 months DAPT at 2-years follow-up in both male and female gender.
Source: Journal of Thrombosis and Thrombolysis - April 13, 2021 Category: Hematology Source Type: research
Intravenous abciximab as a rescue therapy for immediate reocclusion after successful mechanical thrombectomy in acute ischemic stroke patients
Conclusions - Our results underscore a key role for platelet aggregation and the potential of Glycoprotein IIb/IIIa antagonists as a rescue therapy in post-MT immediate reocclusion.PMID:33840346 | DOI:10.1080/09537104.2021.1894326
Source: Platelets - April 12, 2021 Category: Hematology Authors: Fran çois Delvoye Stephane Loyau Julien Labreuche Guillaume Taylor Benjamin Maier Michel Piotin Raphael Blanc Simon Escalard Lucas Di Meglio Malek Ben Maacha Hocine Redjem Stanislas Smajda Gabriele Ciccio Sol ène Hébert Candice Sabben Martine Jandrot-P Source Type: research
Safety and efficacy of low-dose ticagrelor in Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention
Platelets. 2021 Apr 4:1-8. doi: 10.1080/09537104.2021.1909717. Online ahead of print.ABSTRACTIt remains unclear whether low-dose ticagrelor offers better safety and similar efficacy for Asian patients with acute coronary syndromes (ACS). We aimed to compare the safety and effectiveness of low-dose ticagrelor vs standard-dose ticagrelor in Chinese patients with ACS undergoing percutaneous coronary intervention (PCI). In this observational cohort study, a total of 2110 ACS patients who were event-free at 3 months after the index PCI were divided into standard-dose ticagrelor (90 mg twice daily) (n = 1830) or low-dose ticagre...
Source: Platelets - April 5, 2021 Category: Hematology Authors: Yue Wang Beibei Liu Leilei Chen Yue Wang Zhiqiang Wang Xiaojiang Zhang Min Suo Gary S Mintz Xiaofan Wu Source Type: research
