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Ticagrelor monotherapy versus aspirin monotherapy at 12 months after percutaneous coronary intervention: a landmark analysis of the GLOBAL LEADERS trial
CONCLUSIONS: Patients free from events at the end of the first year post-PCI and who adhered to their prescribed regimen had a reduced risk of ischaemic events compared to aspirin monotherapy in the second year post-PCI.CLINICALTRIALS: gov: NCT01813435.PMID:35260381 | DOI:10.4244/EIJ-D-21-00870
Source: EuroIntervention - March 9, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Masafumi Ono Hironori Hara Hideyuki Kawashima Chao Gao Rutao Wang Joanna J Wykrzykowska Jan J Piek Scot Garg Christian Hamm Philippe Gabriel Steg Marco Valgimigli Stephan Windecker Pascal Vranckx Yoshinobu Onuma Patrick W Serruys Source Type: research

A novel risk score to identify the need for triple antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention: a post hoc analysis of the RE-DUAL PCI trial
CONCLUSIONS: Our findings support the use of DAT in the majority of patients. A small subgroup of patients might benefit from TAT and we propose a novel clinical risk score to select these patients.PMID:35105533 | DOI:10.4244/EIJ-D-21-00165
Source: EuroIntervention - February 2, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Bastiaan Zwart Willem Lambertus Bor Anne Johanna Wilhelmina Maria de Veer Bakhtawar Khan Mahmoodi Johannes Christiaan Kelder Gregory Y H Lip Deepak L Bhatt Christopher P Cannon Jurri ën Maria Ten Berg Source Type: research

Safety and Efficacy of Ticagrelor Monotherapy According to Drug-Eluting Stent Type: The TWILIGHT-STENT Study
CONCLUSIONS: As compared with ticagrelor plus aspirin, ticagrelor monotherapy after a short DAPT duration lowered bleeding complications without increasing the ischemic risk, irrespective of DES type. We observed no significant differences among DES-types.PMID:34881696 | DOI:10.4244/EIJ-D-21-00721
Source: EuroIntervention - December 9, 2021 Category: Cardiovascular & Thoracic Surgery Authors: George Dangas Usman Baber Samin K Sharma Gennaro Giustino Samantha Sartori Johny Nicolas Ridhima Goel Shamir R Mehta David J Cohen Dominick J Angiolillo Zhongjie Zhang Anton Camaj Davide Cao Carlo Briguori Dariusz Dudek Javier Escaned Kurt Huber Timothy C Source Type: research

Percutaneous versus surgical transaxillary access for transcatheter aortic valve replacement: a propensity-matched analysis of the US experience
CONCLUSIONS: This study supports the safety and efficacy of percutaneous TAx TAVR compared to traditional surgical cutdown. Percutaneous access was associated with shorter ICU stay and a higher rate of major vascular complication without an increase in life-threatening bleeding.PMID:34794935 | DOI:10.4244/EIJ-D-21-00549
Source: EuroIntervention - November 19, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Christine Chung Tsuyoshi Kaneko Rajiv Tayal Thom G Dahle James M McCabe Source Type: research

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