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Morin and Its Role in Chronic Diseases.
Authors: Sinha K, Ghosh J, Sil PC Abstract Chronic diseases can be referred to the long-term medical conditions which are mostly progressive in nature, i.e., it deteriorates over time. Diabetes, arthritis, heart disease, stroke, cancer, and chronic respiratory problems (e.g., COPD) are not a few examples of chronic diseases and chronic diseases are the leading causes of death and disability all over the world. Chronic diseases and conditions are among the most common, costly, and preventable of all health problems. Affordable cost, presence mostly in the consumables, and minimal side effects make the naturally occu...
Source: Advances in Experimental Medicine and Biology - September 29, 2016 Category: Research Tags: Adv Exp Med Biol Source Type: research

Chronic Health Conditions as a Risk Factor for Falls among the Community-Dwelling US Older Adults: A Zero-Inflated Regression Modeling Approach.
In this study, Behavioral Risk Factor Surveillance System (BRFSS) 2014 participants aged 65 years and older (n = 159,336) were evaluated. It was found that 29.7% (n = 44,550) of the sample experienced at least one fall and 16.3% (n = 20,444) experienced more than one fall in the past 12 months. According to the study findings, having a medical history of stroke, CKD, arthritis, depression, and diabetes independently predict the risk of first-time falling as well as the risk of recurrent falling in older adult population while controlling for other factors. On the other hand, having a medical history of the heart attack, an...
Source: Biomed Res - May 2, 2017 Category: Research Authors: Paliwal Y, Slattum PW, Ratliff SM Tags: Biomed Res Int Source Type: research

Influences of Corydalis decumbens on the Activities of CYP450 Enzymes in Rats with a Cocktail Approach.
Abstract Corydalis decumbens, a Traditional Chinese Medicine, has been widely used for the alternative and/or complementary therapy of hypertension, arrhythmias rheumatoid arthritis, sciatica, stroke, hemiplegia, paraplegia, and vascular embolism. The aim of this study was to determinate the potential effects of Corydalis decumbens on the five cytochrome P450 (CYP) enzyme activities (CYP1A2, CYP3A4, CYP2C9, CYP2C19, and CYP2D6) by cocktail approach. To evaluate whether concurrent use of Corydalis decumbens interferes with the effect of several prescription drugs, saline (control group) or Corydalis decumbens (XTW ...
Source: Biomed Res - February 28, 2019 Category: Research Authors: Cheng C, Qian J, Wang Z, Li W, Huang C, Chen M, Dong Y, Lian L, Sun W Tags: Biomed Res Int Source Type: research

TECHNIQUES Vagus Nerve Stimulation and the Cardiovascular System
The vagus nerve plays an important role in maintaining physiological homeostasis, which includes reflex pathways that regulate cardiac function. The link between vagus nerve activity and the high-frequency component of heart rate variability (HRV) has been well established, correlating with vagal tone. Recently, vagus nerve stimulation (VNS) has been investigated as a therapeutic for a multitude of diseases, such as treatment-resistant epilepsy, rheumatoid arthritis, Crohn's disease, and asthma. Because of the vagus nerve's innervation of the heart, VNS has been identified as a potential therapy for cardiovascular disorder...
Source: Cold Spring Harbor perspectives in medicine - February 2, 2020 Category: Research Authors: Capilupi, M. J., Kerath, S. M., Becker, L. B. Tags: Bioelectronic Medicine TECHNIQUES Source Type: research

Associations between High-Sensitivity C-Reactive Protein and Non-Communicable Diseases in an Asian Population: Findings from the IFLS Study
Biomarkers. 2021 May 29:1-34. doi: 10.1080/1354750X.2021.1936177. Online ahead of print.ABSTRACTThere has been no comprehensive study on how high-sensitivity C-reactive protein (hs-CRP) level, a biomarker of inflammation, is associated with subsequent diagnoses of various non-communicable diseases (NCDs) in Asians. Our study is the first to do so to better compare these associations in an Asian population. This is a nationwide longitudinal study of 3,410 male and 4,004 female participants of the RAND Indonesian Family Life Survey with a mean age of 42.4 years, to examine associations between increasing hs-CRP levels and ri...
Source: Biomarkers - May 31, 2021 Category: Research Authors: Nirmin Juber Chien-Chang Lee Jason J Liu Source Type: research

Effective treatment of intractable diseases using nanoparticles to interfere with vascular supply and angiogenic process
AbstractAngiogenesis is a vital biological process involving blood vessels forming from pre-existing vascular systems. This process contributes to various physiological activities, including embryonic development, hair growth, ovulation, menstruation, and the repair and regeneration of damaged tissue. On the other hand, it is essential in treating a wide range of pathological diseases, such as cardiovascular and ischemic diseases, rheumatoid arthritis, malignancies, ophthalmic and retinal diseases, and other chronic conditions. These diseases and disorders are frequently treated by regulating angiogenesis by utilizing a va...
Source: European Journal of Medical Research - November 4, 2022 Category: Research Source Type: research

Prevalence and influence of hypouricemia on cardiovascular diseases in patients with rheumatoid arthritis
ConclusionsHypouricemia may be a potential risk factor of CVDs in RA patients
Source: European Journal of Medical Research - November 21, 2022 Category: Research Source Type: research

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