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For Your Eyes Only: 007 Tips for the Management of Cardiovascular Risk Factors in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis
J Rheumatol. 2023 Apr 15:jrheum.2023-0219. doi: 10.3899/jrheum.2023-0219. Online ahead of print.ABSTRACTPremature atherosclerosis has been observed during the course of different systemic inflammatory diseases, such as rheumatoid arthritis (RA), systemic lupus erythematosus, and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV).1-3 As a result, cardiovascular (CV) events, including myocardial infarction, stroke, heart failure, coronary artery disease, and death, occur 1.65 to 3 times more commonly in patients with AAV as compared to the general population, and the risk appears to be highest in the firs...
Source: Journal of Rheumatology - April 15, 2023 Category: Rheumatology Authors: Jan Willem Cohen Tervaert Source Type: research
A review on the role of SNHG8 in human disorders
Pathol Res Pract. 2023 Apr 7;245:154458. doi: 10.1016/j.prp.2023.154458. Online ahead of print.ABSTRACTSmall nucleolar RNA host gene 8 (SNHG8) is a long non-coding RNA that has physiological roles in epithelial and muscle satellite cells. This lncRNA has been reported to be over-expressed in a variety of cancer cell lines. Its silencing has attenuated tumor growth in animal models of cancers. SNHG8 can be served as a molecular sponge for some miRNAs to regulate their target genes. miR-634/ZBTB20, miR-335-5p/PYGO2, miR588/ATG7, miR-152/c-MET, miR-1270/BACH1, miR-491/PDGFRA, miR-512-5p/TRIM28, miR-149-5p/PPM1F, miR-542-3p/CC...
Source: Atherosclerosis - April 12, 2023 Category: Cardiology Authors: Soudeh Ghafouri-Fard Atefeh Harsij Bashdar Mahmud Hussen Mohammad Taheri Seyed Abdulmajid Ayatollahi Source Type: research
Galangin as an inflammatory response modulator: An updated overview and therapeutic potential
Chem Biol Interact. 2023 Apr 10:110482. doi: 10.1016/j.cbi.2023.110482. Online ahead of print.ABSTRACTNumerous chronic diseases, such as cancer, diabetes, rheumatoid arthritis, cardiovascular disease, and gastrointestinal disorders, all have an inflammation-based etiology. In cellular and animal models of inflammation, flavonols were used to show potent anti-inflammatory activity. The flavonols enhanced the synthesis of the anti-inflammatory cytokines transforming growth factor and interleukin-10 (IL-10) and reduced the synthesis of the prostaglandins IL-6, tumor necrosis factor-alpha (TNF-α), and prostaglandin E2 (PGE2),...
Source: Chemico-Biological Interactions - April 12, 2023 Category: Molecular Biology Authors: Riya Thapa Obaid Afzal Abdulmalik Saleh Alfawaz Altamimi Ahsas Goyal Waleed Hassan Almalki Sami I Alzarea Imran Kazmi Vikash Jakhmola Sachin Kumar Singh Kamal Dua Ritu Gilhotra Gaurav Gupta Source Type: research
A review on the role of SNHG8 in human disorders
Pathol Res Pract. 2023 Apr 7;245:154458. doi: 10.1016/j.prp.2023.154458. Online ahead of print.ABSTRACTSmall nucleolar RNA host gene 8 (SNHG8) is a long non-coding RNA that has physiological roles in epithelial and muscle satellite cells. This lncRNA has been reported to be over-expressed in a variety of cancer cell lines. Its silencing has attenuated tumor growth in animal models of cancers. SNHG8 can be served as a molecular sponge for some miRNAs to regulate their target genes. miR-634/ZBTB20, miR-335-5p/PYGO2, miR588/ATG7, miR-152/c-MET, miR-1270/BACH1, miR-491/PDGFRA, miR-512-5p/TRIM28, miR-149-5p/PPM1F, miR-542-3p/CC...
Source: Pathology, Research and Practice - April 12, 2023 Category: Pathology Authors: Soudeh Ghafouri-Fard Atefeh Harsij Bashdar Mahmud Hussen Mohammad Taheri Seyed Abdulmajid Ayatollahi Source Type: research
Galangin as an inflammatory response modulator: An updated overview and therapeutic potential
Chem Biol Interact. 2023 Apr 10:110482. doi: 10.1016/j.cbi.2023.110482. Online ahead of print.ABSTRACTNumerous chronic diseases, such as cancer, diabetes, rheumatoid arthritis, cardiovascular disease, and gastrointestinal disorders, all have an inflammation-based etiology. In cellular and animal models of inflammation, flavonols were used to show potent anti-inflammatory activity. The flavonols enhanced the synthesis of the anti-inflammatory cytokines transforming growth factor and interleukin-10 (IL-10) and reduced the synthesis of the prostaglandins IL-6, tumor necrosis factor-alpha (TNF-α), and prostaglandin E2 (PGE2),...
Source: Chemico-Biological Interactions - April 12, 2023 Category: Molecular Biology Authors: Riya Thapa Obaid Afzal Abdulmalik Saleh Alfawaz Altamimi Ahsas Goyal Waleed Hassan Almalki Sami I Alzarea Imran Kazmi Vikash Jakhmola Sachin Kumar Singh Kamal Dua Ritu Gilhotra Gaurav Gupta Source Type: research
