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Condition: Arthritis
Education: Study
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Total 844 results found since Jan 2013.
Child-Pugh Class B or C Liver Disease Increases the Risk of Early Mortality in Patients With Hepatitis C Undergoing Elective Total Joint Arthroplasty Regardless of Treatment Status
CONCLUSION: Patients with HCV and a Child-Pugh Class B or C at the time of elective TJA had substantially increased odds of death, regardless of liver function, cirrhosis, age, Model for End-Stage Liver Disease level, HCV treatment, and viral load status. This is similar to the risk of early mortality observed in patients with chronic liver disease undergoing abdominal and cardiac surgery. Surgeons should avoid these major elective procedures in patients with Child-Pugh Class B or C whenever possible. For patients who feel their arthritic symptoms and pain are unbearable, surgeons need to be clear that the risk of death is...
Source: Clinical Orthopaedics and Related Research - March 24, 2023 Category: Orthopaedics Authors: Kyle H Cichos Eric Jordan Kian Niknam Antonia F Chen Erik N Hansen Gerald McGwin Elie S Ghanem Source Type: research
Multimorbidity and functional disability among older adults - the role of inflammation and glycemic status: An Observational Longitudinal Study
Conclusion: The findings suggest potential for anti-inflammatory management among older women and optimal glycemic control among older men with these particular multimorbidity combinations as focus for therapeutic/preventive options for maintaining functional health.
Source: Gerontology - March 1, 2023 Category: Geriatrics Source Type: research
Reach and Impact of In-Person and Remote Delivery Formats of Walk with Ease
Inquiry. 2023 Jan-Dec;60:469580231152314. doi: 10.1177/00469580231152314.ABSTRACTThis descriptive study retrospectively evaluates the reach and impact of cohorts enrolled in Group (in-person, 2017-2020) and Self-Directed (remote, 2019-2020) delivery formats of the evidenced-based health promotion program, Walk with Ease, implemented statewide in North Carolina. An existing dataset consisting of pre- and post-surveys were analyzed for 1,890 participants; 454 (24%) from the Group format and 1,436 (76%) from Self-Directed. Self-Directed participants were younger, had more years of education, represented more Black/African Ame...
Source: Rural Remote Health - February 21, 2023 Category: Rural Health Authors: Nadia Z Mazza Amy Joy Lanou Serena Weisner Source Type: research
Association between baseline cardiovascular risk and incidence rates of major adverse cardiovascular events and malignancies in patients with psoriatic arthritis and psoriasis receiving tofacitinib
CONCLUSION: In tofacitinib-treated patients with PsA/PsO, increased ASCVD risk and baseline MetS were associated with higher IRs for MACE and malignancies. Our results support assessing CV risk in patients with PsA/PsO and suggest enhanced cancer monitoring in those with increased ASCVD risk.REGISTRATION CLINICALTRIALSGOV: NCT01877668/NCT01882439/NCT01976364/NCT00678210/NCT01710046/NCT01241591/NCT01186744/NCT01276639/NCT01309737/NCT01163253.PLAIN LANGUAGE SUMMARY: People who have psoriatic arthritis or psoriasis may have more heart-related problems and cancer if they have a higher risk of cardiovascular disease: A study in...
Source: Adv Data - February 13, 2023 Category: Epidemiology Authors: Lars E Kristensen Bruce Strober Denis Poddubnyy Ying-Ying Leung Hyejin Jo Kenneth Kwok Ivana Vranic Dona L Fleishaker Lara Fallon Arne Yndestad Dafna D Gladman Source Type: research
A comprehensive meta-analysis comprising 149 case-control studies to investigate the association between IL-6 gene rs1800795 polymorphism and multiple disease risk
CONCLUSION: This meta-analysis provided strong evidence for the association between IL-6 gene rs1800795 polymorphism and multiple disease risks. The IL-6 gene could be a useful prognostic biomarker for CAD, inflammatory disease, ischemic stroke, and rheumatoid arthritis.PMID:36736866 | DOI:10.1016/j.gene.2023.147234
Source: Gene - February 3, 2023 Category: Genetics & Stem Cells Authors: Md Harun-Or-Roshid Md Nurul Haque Mollah None Jesmin Source Type: research
Epidemiology and survival of systemic sclerosis-sarcoidosis overlap syndrome
CONCLUSION: Sarcoidosis in SSc is rare but appears to occur more frequently than the general population. It is associated with pulmonary, lymph node, cutaneous, joint and hepatic involvement. Stroke occurs more frequently in SSc-sarcoidosis patients but with no differences in survival.PMID:36725057 | DOI:10.3899/jrheum.220877
Source: J Rheumatol - February 1, 2023 Category: Rheumatology Authors: Megan Himmel Meyer Balter Zareen Ahmad Elvira Bangert Shafina Hasmani Rhea Siddha Mohammad Movahedi Sindhu R Johnson Source Type: research
