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Dengyinnaotong attenuates atherosclerotic lesions, gut dysbiosis and intestinal epithelial barrier impairment in the high fat diet-fed ApoE < sup > -/- < /sup > mice
CONCLUSIONS: Our work provides novel preclinical evidence that underpins the multifaceted effects of DYNT in the control of atherosclerosis.PMID:37453620 | DOI:10.1016/j.jep.2023.116916
Source: Atherosclerosis - July 15, 2023 Category: Cardiology Authors: Minqi Xiong Zilong Zhang Jingang Cui Xiaoye Du Yu Chen Teng Zhang Source Type: research

Clinical Characteristics  of Inpatients With New-Onset Diabetes Mellitus in Eastern China: Based on Novel Clustering Analysis
ConclusionsThe inpatients with new-onset diabetes in Eastern China had the unique clustering distribution. The clinical characteristics, treatments, and diabetes-related complications and comorbidities of the five subgroups were different, which may provide the basis for precise treatments of diabetes.
Source: Frontiers in Endocrinology - July 27, 2022 Category: Endocrinology Source Type: research

Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
CONCLUSION: Eight biased TCM constitutions were closely related to specific diseases, and could be used to guide individualized prevention and treatment. More rigorously designed studies are recommended to further verify the constitution-disease relationship. PMID: 32744037 [PubMed - in process]
Source: Journal of Traditional Chinese Medicine - July 31, 2020 Category: Complementary Medicine Authors: Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L Tags: J Tradit Chin Med Source Type: research

Association between iron metabolism and cognitive impairment in older non-alcoholic fatty liver disease individuals: A cross-sectional study in patients from a Chinese center
This study examined whether iron metabolism is associated with cognitive impairment in older individuals. A cross-sectional study was held in patients from a Chinese center. Individuals with NAFLD aged over 60 years were included if they did not have excessive alcohol intake and were free of stroke or dementia. Their cognitive function was assessed by the same neurologist. 3.0T H proton magnetic resonance spectroscopy (1H-MRS) was performed to evaluate the hippocampus of the participants without contraindication. t test and Chi-square test were used to analyze the data. Binary logistic regression was used for correlation ...
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

A Novel Deep Neural Network Model for Multi-Label Chronic Disease Prediction
Conclusions concludes this work along with future work. Dataset and Data Preprocessing In the work, we mainly focus on multiple chronic disease classification. It can be formulated into a multi-label classification problem. There are three common chronic diseases are selected from the physical examination records: hypertension (H), diabetes (D), and fatty liver (FL). In the experiments, the physical examination datasets are collected from a local medical center, which contain 110,300 physical examination records from about 80,000 anonymous patients (Li et al., 2017a,b). Sixty-two feature items are selected from over 100...
Source: Frontiers in Genetics - April 23, 2019 Category: Genetics & Stem Cells Source Type: research