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Specialty: Cardiology
Condition: Abdominal Aortic Aneurysm
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Total 81 results found since Jan 2013.
The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis
Curr Opin Lipidol. 2023 Jul 28. doi: 10.1097/MOL.0000000000000890. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: To explore the multiple roles that lysophosphatidic acid (LPA) plays in vascular disease and atherosclerosis.RECENT FINDINGS: A high-fat high-cholesterol diet decreases antimicrobial activity in the small intestine, which leads to increased levels of bacterial lipopolysaccharide in the mucus of the small intestine and in plasma that increase systemic inflammation, and enhance dyslipidemia and aortic atherosclerosis. Decreasing LPA production in enterocytes reduces the impact of the diet. LPA signaling inhibit...
Source: Atherosclerosis - July 27, 2023 Category: Cardiology Authors: Arnab Chattopadhyay Srinivasa T Reddy Alan M Fogelman Source Type: research
Associations of Tissue and Soluble LOX-1 with Human Abdominal Aortic Aneurysm
Conclusions In AAA, sLOX-1 was differently affected by age, cardiometabolic diseases, and corresponding medical therapies. Comparison with nonatherosclerotic disease would be beneficial to further elucidate the diagnostic potential of sLOX-1, although it was not useful for risk stratification. Aneurysmal LOX-1 mRNA expression was increased and positively associated with smooth muscle cells and collagen content, suggesting that LOX-1 is eventually not deleterious in human AAA and could counteract AAA rupture.PMID:37421287 | DOI:10.1161/JAHA.122.027537
Source: Atherosclerosis - July 8, 2023 Category: Cardiology Authors: Anja Hofmann Yazan Khorzom Anna Klimova Steffen Wolk Albert Busch Pamela Sabarstinski Margarete M üglich Dmitry Egorov Irakli Kopaliani David M Poitz Marvin Kapalla Bianca Hamann Frieda Frank Christian J änichen Coy Brunssen Henning Morawietz Christian Source Type: research
Procedural and long-term outcomes of elective endovascular abdominal aortic aneurysm repair in octogenarians
CONCLUSION: In octogenarian patients with AAA, EVAR represents a safe procedure both during the index hospitalization and during long-term follow-up.PMID:37355984 | DOI:10.24875/ACM.22000289
Source: Archivos de Cardiologia de Mexico - June 25, 2023 Category: Cardiology Authors: Fernando Garagoli Juan Guido-Chiabrando Jos é Gaspar-Chas Mart ín Rabellino Ignacio Mart ín Bluro Source Type: research
Outcomes of endovascular repair of infrarenal penetrating aortic ulcers
Conclusions: According to this registry data, endovascular repair of PAU is technically feasible with acceptable perioperative outcomes, but further studies investigating mid- and long-term data are needed before invasive treatment of PAU disease in an elderly and comorbid patient population should be recommended.PMID:36880201 | DOI:10.1024/0301-1526/a001060
Source: Atherosclerosis - March 7, 2023 Category: Cardiology Authors: Johannes Hatzl Christian-Alexander Behrendt Thomas Schmitz-Rixen Reinhart Thomas Grundmann Markus Steinbauer Dittmar B öckler Christian Uhl DIGG Investigators Source Type: research
Comparison of Unibody and Non-Unibody Endografts for Abdominal Aortic Aneurysm Repair in Medicare Beneficiaries: The SAFE-AAA Study
CONCLUSIONS: In the SAFE-AAA Study, unibody endografts failed to meet noninferiority compared with non-unibody endografts with respect to aortic reintervention, rupture, and mortality. These data support the urgency of instituting a prospective longitudinal surveillance program for monitoring safety events related to aortic stent grafts.PMID:36866664 | DOI:10.1161/CIRCULATIONAHA.122.062123
Source: Circulation - March 3, 2023 Category: Cardiology Authors: Eric A Secemsky Yang Song Tianyu Sun Carmen Gacchina Johnson Megan Gatski Li Wang Andrew Farb Robert E Lee Aurko Shaw Jiaman Xu Robert W Yeh Source Type: research
Why do guidelines recommend screening for abdominal aortic aneurysms, but not for asymptomatic carotid stenosis? A Plea for a randomized controlled trial
CONCLUSIONS: Although mass screening should not be recommended, there are several arguments suggesting that selective screening for AsxCS should be considered. The rationale supporting such selective screening is to optimize risk factor control and to initiate intensive medical therapy for prevention of future cardiovascular events, rather than to identify candidates for an intervention.PMID:36162523 | DOI:10.1016/j.ijcard.2022.09.045
Source: Atherosclerosis - September 26, 2022 Category: Cardiology Authors: Kosmas I Paraskevas J David Spence Dimitri P Mikhailidis Pier Luigi Antignani Peter Gloviczki Hans-Henning Eckstein Francesco Spinelli Francesco Stilo Luca Saba Pavel Poredos Alan Dardik Christos D Liapis Armando Mansilha Gianluca Faggioli Rodolfo Pini Ma Source Type: research
Role of DNA damage in the pathogenesis of atherosclerosis
J Cardiol. 2022 Sep 12:S0914-5087(22)00218-0. doi: 10.1016/j.jjcc.2022.08.010. Online ahead of print.ABSTRACTAtherosclerosis is a cause of coronary artery disease, abdominal aortic aneurysm, and stroke. The pathogenesis underlying atherosclerosis is complex but it is clear that inflammation plays a pivotal role. Inflammation in atherosclerosis is triggered by the recognition of intracellular contents released from damaged cells by pattern recognition receptors, and is therefore sterile and chronic. Because the DNA of these cells is damaged, cellular senescence is also involved in this inflammation. Here, we will discuss th...
Source: Journal of Cardiology - September 15, 2022 Category: Cardiology Authors: Mari Ishida Chiemi Sakai Takafumi Ishida Source Type: research
