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Real-World Study Confirms Benefit of XARELTO ® (rivaroxaban) for Secondary Prevention of Venous Thromboembolism in Cancer Patients
TITUSVILLE, NJ, December 9, 2022 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced observational data from eight years of clinical practice showing that the oral Factor Xa inhibitor XARELTO® (rivaroxaban) is associated with comparable effectiveness and safety to the Factor Xa inhibitor apixaban for the treatment of cancer-associated thromboembolism (CAT) in a broad cohort of patients with various cancer types. Patients with CAT are at a higher risk of venous thromboembolism (VTE), which is the second-leading cause of death in people with cancer.1Data from the Observational Study in Cancer-A...
Source: Johnson and Johnson - December 9, 2022 Category: Pharmaceuticals Tags: Latest News Source Type: news

Tumor Embolism Through Right-to-Left Shunt Due to Venous Invasion of Esophageal Carcinoma
A 69-year-old man was admitted to the hospital with right hemiparesis and global aphasia. Perfusion computed tomography imaging revealed ischemic penumbra in the middle cerebral artery territory. Angiography showed left middle cerebral artery occlusion. Mechanical thrombectomy with one pass was performed, and successful recanalization was obtained. Embolic material was retrieved; it contained tumor fragments with atypical keratinizing squamous cell carcinoma. Contrast computed tomography imaging indicated tumor invasion into the superior vena cava, and contrast transcranial Doppler indicated the presence of a right-to-left...
Source: Journal of Stroke and Cerebrovascular Diseases - October 1, 2020 Category: Neurology Authors: Suguru Araki, Kota Maekawa, Kazuto Kobayashi, Takanori Sano, Tadashi Yabana, Masunari Shibata, Fumitaka Miya Tags: Case Report Source Type: research

Medium and long-term risks of specific cardiovascular diseases in survivors of 20 adult cancers: a population-based cohort study using multiple linked UK electronic health records databases
In this study, we used large-scale electronic health records data from multiple linked UK databases to address these evidence gaps.MethodsFor this population-based cohort study, we used linked primary care, hospital, and cancer registry data from the UK Clinical Practice Research Datalink to identify cohorts of survivors of the 20 most common cancers who were 18 years or older and alive 12 months after diagnosis and controls without history of cancer, matched for age, sex, and general practice. We compared risks for a range of cardiovascular disease outcomes using crude and adjusted Cox models. We fitted interactions to in...
Source: The Lancet - August 21, 2019 Category: General Medicine Source Type: research

A Study on Etiopathogenesis of Vocal Cord Paresis and Palsy in a Tertiary Centre
AbstractTo identify patients of vocal cord paresis and palsy and to establish an etiological diagnosis based on a study performed in a tertiary centre. Study was done prospectively in the Department of ENT in KIMS Hospital, Bangalore, for 1  year, from June 2016 to June 2017. 100 patients with vocal cord paresis and palsy were identified and examined by using various tests and investigations to establish the etiology. Most of the patients presented with complaints of change in voice (92%). Some of the other common presenting complaint s included noisy breathing and difficulty in swallowing, difficulty in voice production ...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - October 8, 2018 Category: ENT & OMF Source Type: research

How to Quit Smoking
By Stacy Simon Tobacco use remains the single largest preventable cause of disease and premature death in the United States. Since the release of the Surgeon General’s Report on Smoking and Health 50 years ago, there have been 20 million deaths due to tobacco. Almost half the deaths from 12 different types of cancer combined – including lung, voice box, throat, esophagus, and bladder cancers – are attributable to cigarette smoking alone. In addition to cancer, smoking greatly increases the risk of debilitating long-term lung diseases like emphysema and chronic bronchitis. It also raises the risk for heart...
Source: American Cancer Society :: News and Features - November 16, 2016 Category: Cancer & Oncology Tags: Smoking/Tobacco Source Type: news

A Day in the Life of an Acute Care SLP
Editor’s Note: This is an excerpt from a guest blog post that originally appeared on Tactus Therapy. In the post, speech-language pathologist Brenda Arend shares highlights of a typical day working in acute care at Providence St. Peter Hospital in Olympia, Washington. 8:30 a.m.: Assigning patients The first part of my day is spent opening up patient charts in our EPIC electronic medical record and assigning three SLPs to see patients in our 380-bed hospital. Two or three SLPs cover a caseload that ranges from 15 to 30 patients, although recently we see as many as 42. In addition, we also provide outpatient video fluo...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - June 9, 2016 Category: Speech Therapy Authors: Brenda Arend Tags: Speech-Language Pathology acute care Aphasia Cognitive Rehabilitation Dysphagia Health Care Swallowing Disorders Source Type: blogs

The Feasibility and Outcome of Oro-esophageal Tube Feeding in Patients with Various Etiologies
Abstract The oro-esophageal tube (OE tube) is widely used in dysphagia patients although its success rate for transition to oral feeding is reported only in stroke patients. The aim of this study was to evaluate the feasibility and outcome of OE tube feeding for patients with dysphagia resulting from various etiologies. The authors reviewed the medical records of 1995 dysphagic patients that had undergone videofluoroscopic swallowing study (VFSS) in a tertiary hospital from April 2002 through December 2009. Of these, 97 patients were recommended to use OE tube feeding based on the VFSS findings. Follow-up VFSS wer...
Source: Dysphagia - August 13, 2015 Category: Speech Therapy Source Type: research