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Protection of Salvianolate Lyophilized Injection combined with Xueshuantong Injection (Lyophilized) against focal cerebral ischemia/reperfusion injury in rats through suppression of inflammatory response
ConclusionsThis study shows that SLI combined with XST (1X1S) can protect cerebral ischemia-reperfusion injury due to its anti-inflammatory property, and may provide a potential promising new therapeutic strategy for acute ischemic stroke.
Source: Chinese Herbal Medicines - July 10, 2018 Category: Complementary Medicine Source Type: research

Salvianolate Lyophilized Injection combined with Xueshuantong Injection (Lyophilized) Protects against Focal Cerebral Ischemia/Reperfusion Injury in Rats through Suppression of the Inflammatory Response
Conclusions This study shows that SLI combined with XST (1 × 1S) can protect cerebral ischemia-reperfusion injury due to its anti-inflammatory property, and may provide a potential promising new therapeutic strategy for acute ischemic stroke.
Source: Chinese Herbal Medicines - December 29, 2017 Category: Complementary Medicine Source Type: research

Protective Effects of Spatholobi Caulis Extract on Neuronal Damage and Focal Ischemic Stroke/Reperfusion Injury
AbstractNeuronal apoptotic cell death plays an important role in many neurological disorders, including Alzheimer ’s disease, Parkinson’s disease, and ischemic stroke. Spatholobi Caulis (SC) has been widely used in traditional herbal medicine for the treatment of cancer, inflammation, viral infection, and anemia. However, the protective effects of SC extract (SCE) against apoptotic cell death in the brain h ave not been reported. We investigated the protective effects of SCE against neuronal injury etoposide-induced neurotoxicity and in rats subjected to focal transient ischemic stroke middle cerebral artery occlusion ...
Source: Molecular Neurobiology - July 13, 2017 Category: Neurology Source Type: research

Panax notoginseng saponins administration modulates pro- /anti-inflammatory factor expression and improves neurologic outcome following permanent MCAO in rats
AbstractIschemic stroke, particularly permanent occlusion, accounts for the overwhelming majority of all strokes. In addition to the occlusion of arteries, the inflammatory response plays a pivotal role in the severity of the cerebral injury and its clinical prognosis. Here,panax notoginseng saponins (PNS) extracted from a traditional Chinese herbal medicine was administered following permanent middle cerebral artery occlusion (MCAO) in rats to explore the neuroprotective mechanisms against ischemic injury. The results showed that MCAO surgery was successful in producing an infarct and that PNS and nimodipine could amelior...
Source: Metabolic Brain Disease - September 1, 2016 Category: Neurology Source Type: research

Rooibos: Better Than Green Tea For Many Reasons
When I hiked Table Mountain on my last trip to South Africa, the locals told me about an herb that is better than green tea that kept them disease-free. African Bushmen have used this herb since before recorded history, but it’s still pretty rare here in America. Studies on this plant are being done all over the world. But not in the U.S. Because Big Pharma and the FDA aren’t interested in a natural cure that can’t be patented — or profited from. What is This South African Herb? I’m talking about an herb called Rooibos — or red bush in Afrikaans. Rooibos (pronounced roy-boss) provides a whole lo...
Source: Al Sears, MD Natural Remedies - May 27, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Natural Cures Source Type: news

Clinacanthus nutans Protects Cortical Neurons Against Hypoxia-Induced Toxicity by Downregulating HDAC1/6
This study further opens a new avenue for the use of herbal medicines to regulate epigenetic control of brain injury.
Source: NeuroMolecular Medicine - May 9, 2016 Category: Neurology Source Type: research

Pinkies Up! There Could Be Some Real Health Benefits To Drinking Tea
Tea gets short shrift as coffee’s milder little sister. But these leaves may have a lot more to offer drinkers than just their subtle taste. Large, observational studies have found lifelong tea drinkers are less likely to face early cognitive decline and get certain types of cancer, stroke, coronary heart disease, and type 2 diabetes. We should also note that by “tea,” we mean the leaves from the Camellia sinensis plant that are plucked and processed in different ways to make black, green, white, oolong and pu’er teas -- not herbal infusions like peppermint, hibiscus and chamomile teas. Researchers ...
Source: Healthy Living - The Huffington Post - March 25, 2016 Category: Consumer Health News Source Type: news

The neuroprotective effect of a traditional herbal (kyung‐ok‐ko) on transient middle cerebral artery occlusion‐Induced ischemic rat brain
We examined whether KOK improves functional recovery and has a neuroprotective effect on infarction volume after transient middle cerebral artery occlusion (MCAO). KOK (50, 100, and 200 mg/kg) was administered orally following reperfusion and twice per day for 14 days post‐MCAO. Infarction volume was measured using 2% 2‐3‐5 triphenylterazolium (TTC) staining at 14 days post‐MCAO and alteration in regional cerebral blood flow (rCBF) after KOK treatment was monitored. Functional improvement was evaluated using adhesive removal and treadmill tests at 1, 7, and 14 days post‐MCAO. Also, apoptotic cell death was assess...
Source: International Journal of Imaging Systems and Technology - May 19, 2015 Category: Radiology Authors: Sang-In Park, Jin‐Hee Lee, Yong‐An Chung, Moon‐Seo Park, Hyun Sunwoo, Kwan‐Sung Lee, Yun‐Young Sunwoo Tags: Research Article Source Type: research

Magnolol protects neurons against ischemia injury via the downregulation of p38/MAPK, CHOP and nitrotyrosine.
Abstract Magnolol is isolated from the herb Magnolia officinalis, which has been demonstrated to exert pharmacological effects. Our aim was to investigate whether magnolol is able to act as an anti-inflammatory agent bring about neuroprotection using a global ischemic stroke model and to determine the mechanisms involved. Rats were treated with and without magnolol after ischemia reperfusion brain injury by occlusion of the two common carotid arteries. The inflammatory cytokine production in serum and the volume of infarction in the brain were measured. The proteins present in the brains obtained from the stroke a...
Source: Toxicology and Applied Pharmacology - July 16, 2014 Category: Toxicology Authors: Chen JH, Kuo HC, Lee KF, Tsai TH Tags: Toxicol Appl Pharmacol Source Type: research

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