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Cancer: Colorectal Cancer
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Total 470 results found since Jan 2013.
Increased standardised incidence ratio of cardiovascular diseases among colorectal cancer patients
ConclusionsColorectal cancer patients are at an increased risk of developing CVD, especially coronary heart disease, during the first 3 years following colorectal cancer diagnosis.
Source: International Journal of Colorectal Disease - March 17, 2022 Category: Gastroenterology Source Type: research
Total, red and processed meat consumption and human health: an umbrella review of observational studies
Int J Food Sci Nutr. 2022 Mar 15:1-12. doi: 10.1080/09637486.2022.2050996. Online ahead of print.ABSTRACTMeat consumption has represented an important evolutionary step for humans. However, modern patterns of consumption, including excess intake, type of meat and cooking method have been the focus of attention as a potential cause of rise in non-communicable diseases. The aim of this study was to investigate the association between total, red and processed meat with health outcomes and to assess the level of evidence by performing a systematic search of meta-analyses of prospective cohort studies. Convincing evidence of th...
Source: International Journal of Food Sciences and Nutrition - March 16, 2022 Category: Nutrition Authors: Giuseppe Grosso Sandro La Vignera Rosita A Condorelli Justyna Godos Stefano Marventano Maria Tieri Francesca Ghelfi Lucilla Titta Alessandra Lafranconi Angelo Gambera Elena Alonzo Salvatore Sciacca Silvio Buscemi Sumantra Ray Daniele Del Rio Fabio Galvano Source Type: research
Increased standardised incidence ratio of cardiovascular diseases among colorectal cancer patients
ConclusionsColorectal cancer patients are at an increased risk of developing CVD, especially coronary heart disease, during the first 3 years following colorectal cancer diagnosis.
Source: International Journal of Colorectal Disease - March 17, 2022 Category: Gastroenterology Source Type: research
Impact of Comorbidities on Lung Cancer Screening Evaluation
CONCLUSION: Patient and procedure-level factors may alter the benefits of lung cancer screening. Data concerning individual risk factors and high-risk complications should therefore be incorporated into diagnostic algorithms to optimize clinical benefit and minimize harm. Further study and validation of the risk factors identified herein are warranted.PMID:35641376 | DOI:10.1016/j.cllc.2022.03.012
Source: Clinical Prostate Cancer - May 31, 2022 Category: Cancer & Oncology Authors: Eric M Robinson Benjamin Y Liu Keith Sigel Chung Yin Juan Wisnivesky Minal S Kale Source Type: research
Cardiovascular Disease Risk Among Cancer Survivors: The Atherosclerosis Risk In Communities (ARIC) Study
CONCLUSIONS: Compared with persons without cancer, adult cancer survivors have significantly higher risk of CVD, especially HF, independent of traditional cardiovascular risk factors. There is an unmet need to define strategies for CVD prevention in this high-risk population.PMID:35772913 | DOI:10.1016/j.jacc.2022.04.042
Source: Atherosclerosis - June 30, 2022 Category: Cardiology Authors: Roberta Florido Natalie R Daya Chiadi E Ndumele Silvia Koton Stuart D Russell Anna Prizment Roger S Blumenthal Kunihiro Matsushita Yejin Mok Ashley S Felix Josef Coresh Corinne E Joshu Elizabeth A Platz Elizabeth Selvin Source Type: research
PARP14 regulates EP4 receptor expression in human colon cancer HCA-7 cells
Biochem Biophys Res Commun. 2022 Jul 19;623:133-139. doi: 10.1016/j.bbrc.2022.07.055. Online ahead of print.ABSTRACTE type prostanoid 4 (EP4) receptors and their signaling pathways have been implicated in the development and malignant transformation of colorectal cancer. We herein demonstrated that the mono(ADP-ribosyl)ation of histone deacetylase (HDAC)1 and HDAC2 by poly(ADP-ribose) polymerase 14 (PARP14) may be required to induce the expression of EP4 receptors. The suppression of PARP14 activity by siRNA and/or its inhibitors reduced the mRNA expression of EP4 receptors. Thus, the expression of their proteins to approx...
Source: Biochemical and Biophysical Research communications - August 1, 2022 Category: Biochemistry Authors: Masato Mashimo Asuka Shimizu Aimi Mori Ayaka Hamaguchi Keijo Fukushima Naofumi Seira Takeshi Fujii Hiromichi Fujino Source Type: research
Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases
Vasa. 2022 Oct 6. doi: 10.1024/0301-1526/a001031. Online ahead of print.ABSTRACT Vascular adhesion protein-1 (VAP-1) also known as amino oxidase copper containing 3 (AOC3) is a pro-inflammatory and versatile molecule with adhesive and enzymatic properties. VAP-1 is a primary amine oxidase belonging to the semicarbazide-sensitive amine oxidase (SSAO) family, which catalyzes the oxidation of primary amines leading to the production of ammonium, formaldehyde, methylglyoxal, and hydrogen peroxide. VAP-1 is mainly expressed by endothelial cells, smooth muscle cells, adipocytes and pericytes. It is involved in a repertoire of bi...
Source: VASA. Zeitschrift fur Gefasskrankheiten. Journal for Vascular Diseases - October 6, 2022 Category: Surgery Authors: Marianna Danielli Roisin Clare Thomas Lauren Marie Quinn Bee Kang Tan Source Type: research
