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Total 1065 results found since Jan 2013.

Cardiovascular imaging techniques for the assessment of coronary artery disease
Br J Hosp Med (Lond). 2022 Aug 2;83(8):1-11. doi: 10.12968/hmed.2022.0176. Epub 2022 Aug 19.ABSTRACTCoronary artery disease continues to be the leading cause of morbidity and mortality worldwide. Recent clinical trials have not demonstrated any mortality benefit of percutaneous coronary intervention compared to medical management alone in the treatment of stable angina. While invasive coronary angiography remains the gold standard for diagnosing coronary artery disease, it comes with significant risks, including myocardial infarction, stroke and death. There have been significant advances in imaging techniques to diagnose ...
Source: British Journal of Hospital Medicine - September 6, 2022 Category: Internal Medicine Authors: Raheel Ahmed Caleb Carver James Rj Foley Graham J Fent Pankaj Garg David P Ripley Source Type: research

COVID-19 Can Increase Risk of Psychiatric Disorders for Up to Two Years
The increased risk of depression and anxiety that patients experience after developing COVID-19 typically subsides within two months, according to astudy published yesterday inThe Lancet Psychiatry. However, patients may have an elevated risk for developing other psychiatric and neurological conditions, such as psychosis, brain fog, and seizures, for up to two years after their infections.“The results have important implications for patients and health services as it suggests new cases of neurological conditions linked to COVID-19 infection are likely to occur for a considerable time after the pandemic has subsided,” s...
Source: Psychiatr News - August 18, 2022 Category: Psychiatry Tags: adults anxiety brain fog children COVID-19 delta dementia depression older adults omicron psychotic disorder seizures The Lancet Psychiatry Source Type: research

Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups
CONCLUSIONS: Any benefit of inhibiting IL-6 signaling for CVD risk reduction is likely to be proportional to absolute reductions in hsCRP levels. Therapeutic inhibition of IL-6 signaling for CVD risk reduction should therefore prioritize those individuals with the highest baseline levels of hsCRP.PMID:35948913 | DOI:10.1186/s12916-022-02446-6
Source: Atherosclerosis - August 10, 2022 Category: Cardiology Authors: Marios K Georgakis Rainer Malik Tom G Richardson Joanna M M Howson Christopher D Anderson Stephen Burgess G Kees Hovingh Martin Dichgans Dipender Gill Source Type: research

Association of an evolutionary-concordance lifestyle pattern score with cardiovascular disease incidence among Black and White men and women
Br J Nutr. 2022 Aug 9:1-28. doi: 10.1017/S0007114522002549. Online ahead of print.ABSTRACTDietary and lifestyle evolutionary discordance is hypothesized to play a role in the etiology of cardiovascular disease (CVD), including coronary heart disease (CHD), and stroke. We aimed to investigate associations of a previously-reported, total (dietary plus lifestyle) evolutionary-concordance (EC) pattern score with incident CVD, CHD, and stroke. We used multivariable Cox proportional hazards regression to investigate associations of the EC score with CVD, CHD, and stroke incidence among United States Black and White men and women...
Source: The British Journal of Nutrition - August 9, 2022 Category: Nutrition Authors: Ziling Mao Alyssa N Troeschel Suzanne Judd James M Shikany Emily B Levitan Monika M Safford Roberd M Bostick Source Type: research

ASPECT Score and Its Application to Vasospasm in Aneurysmal Subarachnoid Haemorrhage: a Case –Control Study
AbstractDelayed cerebral ischaemia (DCI) is a significant complication of aneurysmal subarachnoid haemorrhage (aSAH) and is strongly associated with poorer outcome. The Alberta Stroke Program Early Computer Tomography (ASPECT) score is an established scoring tool, used in acute ischaemic stroke, to quantify early ischaemic changes on CT head scans. We aim to identify if ASPECT scoring correlates with functional outcome in DCI following aSAH. Retrospective case –control study. Inclusion criteria: admission to the Department of Neurosurgery at Leeds Teaching Hospitals NHS Trust (a tertiary neurosurgical centre in the Unite...
Source: Translational Stroke Research - August 9, 2022 Category: Neurology Source Type: research

Carotid artery disease: knowing the numbers
This article discusses the evidence outlining the epidemiology, measurement and surgical management of carotid artery stenosis that inform national guidelines. Vascular and non-vascular trainees should understand these guidelines because of the potentially debilitating or fatal consequences of untreated carotid stenosis.PMID:35938764 | DOI:10.12968/hmed.2022.0184
Source: British Journal of Hospital Medicine - August 8, 2022 Category: Internal Medicine Authors: Adam Heyes Alexander Crichton Sriram Rajagopalan Source Type: research