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Infectious Disease: Herpes

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Total 11557 results found since Jan 2013.

Etiology and clinical characteristics of acute viral hepatitis in South Korea during 2020-2021: a prospective multicenter study
Sci Rep. 2023 Aug 31;13(1):14271. doi: 10.1038/s41598-023-40775-5.ABSTRACTThis prospective, 12-center study investigated the etiology and clinical characteristics of acute viral hepatitis (AVH) during 2020-2021 in South Korea, and the performance of different diagnostic methods for hepatitis E virus (HEV). We enrolled 428 patients with acute hepatitis, of whom 160 (37.4%) were diagnosed with AVH according to predefined serologic criteria. The clinical data and risk factors for AVH were analyzed. For hepatitis E patients, anti-HEV IgM and IgG were tested with two commercial ELISA kits (Abia and Wantai) with HEV-RNA real-tim...
Source: Herpes - August 31, 2023 Category: Infectious Diseases Authors: Chan Young Jeong Gwang Hyeon Choi Eun Sun Jang Young Seok Kim Youn-Jae Lee In Hee Kim Sung Bum Cho Jae Hyun Yoon Kyung-Ah Kim Dae Hee Choi Woo Jin Chung Hyun-Jin Cho Seong Kyun Na Yun-Tae Kim Byung Seok Lee Sook-Hyang Jeong Source Type: research

Oral verrucous Carcinoma on mandibular right alveolar region
BMJ Case Rep. 2023 Aug 30;16(8):e256239. doi: 10.1136/bcr-2023-256239.ABSTRACTVerrucous carcinoma, a low-grade variant of squamous cell carcinoma, defined as a diagnostically squamous cell neoplasia involving lip, oropharyngeal, and laryngeal mucosa and named as 'Ackerman's tumour' by Ackerman in 1948. It usually occurs in the lower lip region and this is one such case in which a painful proliferative growth was evident over the right alveolar region for the period of 8 months. Radiological investigations, biopsies were performed followed by surgical excision of the lesion.PMID:37648278 | DOI:10.1136/bcr-2023-256239
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Ranjjith Ravichandar Sivasankari Thirunavukarasu Jagat Reddy Sathyanarayanan Ramanujam Source Type: research

Arbidol: The current demand, strategies, and antiviral mechanisms
CONCLUSION: ARB is a broad-spectrum antiviral drug that inhibits several viruses in vivo and in vitro, with high safety profile and low resistance; the antiviral mechanisms of ARB deserve to be further explored and more high-quality clinical studies are required to establish the efficacy and safety of ARB.PMID:37647451 | DOI:10.1002/iid3.984
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Yue Kang Yin Shi Silu Xu Source Type: research

ER stress induces caspase-2-tBID-GSDME-dependent cell death in neurons lytically infected with herpes simplex virus type 2
In conclusion, lytic HSV infection in neurons activates an ER stress-driven pathway to execute GSDME-mediated cell death and promote inflammation.PMID:37646198 | DOI:10.15252/embj.2022113118
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Fanghui Ren Ryo Narita Ahmad S Rashidi Stefanie Fruhw ürth Zongliang Gao Rasmus O Bak Martin K Thomsen Georges Mgm Verjans Line S Reinert S øren R Paludan Source Type: research

Recurrent Erythema Multiforme Major Following COVID-19 Infection
Cureus. 2023 Jul 29;15(7):e42646. doi: 10.7759/cureus.42646. eCollection 2023 Jul.ABSTRACTErythema multiforme (EM) is a rare and potentially serious skin condition that can present as a myriad of mucocutaneous lesions. EM can be commonly confused with other cutaneous etiologies, leading to misdiagnosis and delay in proper treatment. This paper describes a case of recurrent erythema multiforme following COVID-19 infection in a 34-year-old male with no prior medical history. The patient had an extensive rash of the oral and genital mucosal areas, diffuse cutaneous involvement, and an extended length of recovery. This unexpec...
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Kayla Rykiel Julian Melchor Ian Motie Kevin Mulles Vida Farhangi Source Type: research

Oral verrucous Carcinoma on mandibular right alveolar region
BMJ Case Rep. 2023 Aug 30;16(8):e256239. doi: 10.1136/bcr-2023-256239.ABSTRACTVerrucous carcinoma, a low-grade variant of squamous cell carcinoma, defined as a diagnostically squamous cell neoplasia involving lip, oropharyngeal, and laryngeal mucosa and named as 'Ackerman's tumour' by Ackerman in 1948. It usually occurs in the lower lip region and this is one such case in which a painful proliferative growth was evident over the right alveolar region for the period of 8 months. Radiological investigations, biopsies were performed followed by surgical excision of the lesion.PMID:37648278 | DOI:10.1136/bcr-2023-256239
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Ranjjith Ravichandar Sivasankari Thirunavukarasu Jagat Reddy Sathyanarayanan Ramanujam Source Type: research

Arbidol: The current demand, strategies, and antiviral mechanisms
CONCLUSION: ARB is a broad-spectrum antiviral drug that inhibits several viruses in vivo and in vitro, with high safety profile and low resistance; the antiviral mechanisms of ARB deserve to be further explored and more high-quality clinical studies are required to establish the efficacy and safety of ARB.PMID:37647451 | DOI:10.1002/iid3.984
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Yue Kang Yin Shi Silu Xu Source Type: research

ER stress induces caspase-2-tBID-GSDME-dependent cell death in neurons lytically infected with herpes simplex virus type 2
In conclusion, lytic HSV infection in neurons activates an ER stress-driven pathway to execute GSDME-mediated cell death and promote inflammation.PMID:37646198 | DOI:10.15252/embj.2022113118
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Fanghui Ren Ryo Narita Ahmad S Rashidi Stefanie Fruhw ürth Zongliang Gao Rasmus O Bak Martin K Thomsen Georges Mgm Verjans Line S Reinert S øren R Paludan Source Type: research

Recurrent Erythema Multiforme Major Following COVID-19 Infection
Cureus. 2023 Jul 29;15(7):e42646. doi: 10.7759/cureus.42646. eCollection 2023 Jul.ABSTRACTErythema multiforme (EM) is a rare and potentially serious skin condition that can present as a myriad of mucocutaneous lesions. EM can be commonly confused with other cutaneous etiologies, leading to misdiagnosis and delay in proper treatment. This paper describes a case of recurrent erythema multiforme following COVID-19 infection in a 34-year-old male with no prior medical history. The patient had an extensive rash of the oral and genital mucosal areas, diffuse cutaneous involvement, and an extended length of recovery. This unexpec...
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Kayla Rykiel Julian Melchor Ian Motie Kevin Mulles Vida Farhangi Source Type: research

Peripheral Nerve Stimulation of the Lesser Occipital and Greater Auricular Nerve for Post Herpetic Neuralgia in a Case of Ramsay Hunt Syndrome: Case Report
CONCLUSIONS: PNS is an effective and safe option for the treatment of chronic pain, and we present a report of successful treatment of PHN in a particularly difficult anatomic distribution. PNS of the lesser occipital and greater auricular nerves is a novel treatment for PHN and shows promise as an effective, safe therapy when other treatment fails.PMID:37641792 | PMC:PMC10460630 | DOI:10.52965/001c.85149
Source: Herpes - August 29, 2023 Category: Infectious Diseases Authors: Brooks Johnson Stephen Covington Mostafa Maita Natalie Strand Source Type: research

Dermatological manifestations associated with COVID-19 and COVID-19 vaccination: results from the Lebanese COVID registry
CONCLUSION: This Lebanese registry adds more robust evidence that clinical manifestations of the COVID-19 virus and vaccine are diverse. More studies are necessary to establish the pathophysiology of these dermatological findings in the context of COVID-19 infection and vaccination.PMID:37638543 | DOI:10.1111/ijd.16815
Source: Herpes - August 28, 2023 Category: Infectious Diseases Authors: Remie Chrabieh Isabelle Haddad Pascale Salameh Mazen Kurban Elio Kechichian Maya Habre Nakhle Ayoub Gretta Torbey Fouad El Sayed Micheline Maamari Zeina Tannous Anna Farra Lebanese COVID Rash Consortium Jinane El Khoury Source Type: research

Silent Myocardial Infarction: A Case Report
We present a case of a 59-year-old overweight woman with prediabetes, primary hypertension, and hypercholesterolemia who presented for herpes zoster (HZ) follow-up; she reported having skipped heartbeats and heart rate fluctuations during the review of systems. On further workup, ECG revealed low voltage QRS complexes, flat QRS complexes, flat T waves, and pathological Q waves, suggesting the diagnosis of SMI. Based on the identified risk factors, including high BMI, prediabetes, primary hypertension, hypercholesterolemia, HZ, and newly diagnosed SMI, the patient was advised to continue with lisinopril 20 mg daily, prescri...
Source: Herpes - August 28, 2023 Category: Infectious Diseases Authors: Maria V Kolesova Suzanne Minor Source Type: research

Tenofovir vaginal film as a potential MPT product against HIV-1 and HSV-2 acquisition: formulation development and preclinical assessment in non-human primates
Front Reprod Health. 2023 Aug 10;5:1217835. doi: 10.3389/frph.2023.1217835. eCollection 2023.ABSTRACTTenofovir (TFV) is an adenosine nucleotide analog with activity against HIV and HSV-2. Secondary analyses of clinical trials evaluating TFV gel as pre-exposure prophylaxis (PrEP) for HIV have shown that gel formulations of TFV provide significant protection against both HIV and HSV-2 acquisition in women who had evidence of use. An alternate quick-dissolving polymeric thin film, to deliver TFV (20 and 40 mg) has been developed as a potential multipurpose technology (MPT) platform. Film formulation was developed based on exc...
Source: Herpes - August 28, 2023 Category: Infectious Diseases Authors: Sravan Kumar Patel Hrushikesh Agashe Dorothy L Patton Yvonne Sweeney May A Beamer Craig W Hendrix Sharon L Hillier Lisa C Rohan Source Type: research

COVID-19 and herpes zoster: a call to action
Front Public Health. 2023 Aug 10;11:1200353. doi: 10.3389/fpubh.2023.1200353. eCollection 2023.NO ABSTRACTPMID:37637810 | PMC:PMC10448515 | DOI:10.3389/fpubh.2023.1200353
Source: Herpes - August 28, 2023 Category: Infectious Diseases Authors: Mohammed Noushad Mohammad Zakaria Nassani Abdulaziz Samran Mohiddin R Dimashkieh Mohammed Sadeg Al-Awar Source Type: research