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Source: Oncology Letters

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Total 421 results found since Jan 2013.

Prognostic significance of TM4SF1 and DDR1 expression in epithelial ovarian cancer
Oncol Lett. 2023 Aug 30;26(4):448. doi: 10.3892/ol.2023.14035. eCollection 2023 Oct.ABSTRACTTransmembrane 4 L6 family member 1 (TM4SF1) and discoidin domain receptor 1 (DDR1) are expressed in numerous types of cancer, but their expression in epithelial ovarian cancer and the association between their expression and patient prognosis are unclear. The present study aimed to explore the expression of TM4SF1 and DDR1 and their relationship with prognosis in epithelial ovarian cancer. Firstly, the Oncomine and Gene Expression Profiling Interactive Analysis (GEPIA) platforms were used to compare the expression levels of TM4SF1 a...
Source: Oncology Letters - September 18, 2023 Category: Cancer & Oncology Authors: Zhijiong Huang Hongyu Yao Zhijun Yang Source Type: research

Diagnostic value of MRI radiomics in differentiating high ‑grade glioma from low‑grade glioma: A meta‑analysis
Oncol Lett. 2023 Aug 23;26(4):436. doi: 10.3892/ol.2023.14023. eCollection 2023 Oct.ABSTRACTNo clear conclusions have yet been reached regarding the accuracy of magnetic resonance imaging (MRI) radiomics in distinguishing high-grade glioma (HGG) from low-grade glioma (LGG). In the present study, a meta-analysis was conducted to determine the diagnostic value of MRI radiomics in differentiating between HGG and LGG, in order to guide their clinical diagnosis. PubMed, Embase and the Cochrane Library databases were searched up to November 2022. The search included studies in which true positive, false positive, true negative a...
Source: Oncology Letters - September 4, 2023 Category: Cancer & Oncology Authors: Jiefang Wang Zhichao Chen Jieyun Chen Source Type: research

Upregulation of long non ‑coding RNA LINC00460 in EGFR‑mutant lung cancer indicates a poor prognosis in patients treated with osimertinib
In conclusion, the upregulation of LINC00460, the expression of which is implicated in osimertinib resistance, in the primary site and plasma of patients with EGFR mutation-positive lung cancer may be associated with a poor prognosis in those treated with osimertinib.PMID:37559586 | PMC:PMC10407845 | DOI:10.3892/ol.2023.13966
Source: Oncology Letters - August 10, 2023 Category: Cancer & Oncology Authors: Yuta Nakano Kazutoshi Isobe Takahiro Yoshizawa Naohisa Urabe Sakae Homma Kazuma Kishi Source Type: research

Targeting transient receptor potential canonical 1 reduces non ‑small cell lung cancer chemoresistance and stemness via inhibition of PI3K/AKT signaling
In conclusion, the results of the current study suggested that targeting TRPC1 could attenuate cancer stemness and chemoresistance via suppression of PI3K/AKT signaling in NSCLC.PMID:37153044 | PMC:PMC10157351 | DOI:10.3892/ol.2023.13810
Source: Oncology Letters - May 8, 2023 Category: Cancer & Oncology Authors: Jiahui Jin Xinyu Yan Yaru Zhao Haojie Zhang Kai Zhuang Yating Wen Jingjing He Junzhen Gao Source Type: research

Cetuximab or nimotuzumab in combination with chemotherapy for treating recurrent/metastatic nasopharyngeal carcinoma: A meta ‑analysis and systemic review
In conclusion, the use of CTX or NTZ in combination with chemotherapy may be a feasible and safe option for treating RM-NPC.PMID:37123019 | PMC:PMC10131271 | DOI:10.3892/ol.2023.13790
Source: Oncology Letters - May 1, 2023 Category: Cancer & Oncology Authors: Xiaoling Ni Junqi Zhang De Zhu Qing Du Jun Yang Hong Cheng Yue Source Type: research