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Source: Oncology Letters
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Total 421 results found since Jan 2013.
Revisiting therapeutic strategies for ovarian cancer by focusing on redox homeostasis
Oncol Lett. 2022 Mar;23(3):80. doi: 10.3892/ol.2022.13200. Epub 2022 Jan 11.ABSTRACTRecent advances in molecular genetics have expanded our understanding of ovarian cancer. High levels of reactive oxygen species (ROS) and upregulation of antioxidant genes are common characteristic features of human cancers. This review reconsiders novel therapeutic strategies for ovarian cancer by focusing on redox homeostasis. A literature search was performed for preclinical and clinical studies published between January 1998 and October 2021 in the PubMed database using a combination of specific terms. ROS serves a central role in tumor...
Source: Oncology Letters - February 3, 2022 Category: Cancer & Oncology Authors: Hiroshi Kobayashi Shogo Imanaka Hiroshi Shigetomi Source Type: research
Evaluation of dyskerin expression and the Cajal body protein WRAP53 β as potential prognostic markers for patients with primary vaginal carcinoma
This study demonstrates that upregulation of dyskerin is significantly associated with poor prognosis. Thus, dyskerin may serve as a promising prognostic marker and a potential putative therapeutic target in PVC.PMID:34868367 | PMC:PMC8630817 | DOI:10.3892/ol.2021.13148
Source: Oncology Letters - December 6, 2021 Category: Cancer & Oncology Authors: Cecilia Ranhem Gabriella Lillsunde Larsson David Lindqvist Bengt Sorbe Mats G Karlsson Marianne Farnebo Kristina Hellman Larysa Kovaleska Elena Kashuba Sonia Andersson Source Type: research
