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Source: Oncology Letters

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Total 421 results found since Jan 2013.

Cetuximab or nimotuzumab in combination with chemotherapy for treating recurrent/metastatic nasopharyngeal carcinoma: A meta ‑analysis and systemic review
In conclusion, the use of CTX or NTZ in combination with chemotherapy may be a feasible and safe option for treating RM-NPC.PMID:37123019 | PMC:PMC10131271 | DOI:10.3892/ol.2023.13790
Source: Oncology Letters - May 1, 2023 Category: Cancer & Oncology Authors: Xiaoling Ni Junqi Zhang De Zhu Qing Du Jun Yang Hong Cheng Yue Source Type: research

Role of FBXW7 expression in gastric cancer: Meta ‑analysis and bioinformatics analysis
Oncol Lett. 2023 Mar 24;25(5):184. doi: 10.3892/ol.2023.13770. eCollection 2023 May.ABSTRACTF-box/WD repeat domain-containing 7 (FBXW7, also known as CDC4) is a member of the F-box protein family, which is a component of the E3 ubiquitin ligase complex. There is an association between expression of FBXW7 and the prognosis of gastric cancer. Therefore, the search for novel tumor biomarkers is key to predict the occurrence, recurrence and metastasis of gastric cancer. In the present study, systematic meta-analysis and bioinformatics analysis were performed to determine the expression levels of prognostic marker FBXW7 in gast...
Source: Oncology Letters - April 28, 2023 Category: Cancer & Oncology Authors: Jing Sun Yang-Kai Bai Zhi-Gang Fan Source Type: research

Exploring the mechanism of an active ingredient of ginger, dihydrocapsaicin, on triple negative breast cancer based on network pharmacology and < em > in  vitro < /em > experiments
Oncol Lett. 2023 Apr 3;25(5):195. doi: 10.3892/ol.2023.13781. eCollection 2023 May.ABSTRACTTo investigate the potential mechanism of ginger in the treatment of triple-negative breast cancer (TNBC) based on network pharmacology, molecular docking and in vitro cell experiments. The Traditional Chinese Medicine Systems Pharmacology Database And Analysis Platform, the Bioinformatics Analysis Tool For Molecular Mechanism Of Traditional Chinese Medicine and the HERB database and literature search were used to search for the main active compounds of ginger. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment anal...
Source: Oncology Letters - April 28, 2023 Category: Cancer & Oncology Authors: Liming Luo Yuran Chen Qiuting Ma Yun Huang Tao Hong Kun Shu Zhiyong Liu Source Type: research

Role of FBXW7 expression in gastric cancer: Meta ‑analysis and bioinformatics analysis
Oncol Lett. 2023 Mar 24;25(5):184. doi: 10.3892/ol.2023.13770. eCollection 2023 May.ABSTRACTF-box/WD repeat domain-containing 7 (FBXW7, also known as CDC4) is a member of the F-box protein family, which is a component of the E3 ubiquitin ligase complex. There is an association between expression of FBXW7 and the prognosis of gastric cancer. Therefore, the search for novel tumor biomarkers is key to predict the occurrence, recurrence and metastasis of gastric cancer. In the present study, systematic meta-analysis and bioinformatics analysis were performed to determine the expression levels of prognostic marker FBXW7 in gast...
Source: Oncology Letters - April 28, 2023 Category: Cancer & Oncology Authors: Jing Sun Yang-Kai Bai Zhi-Gang Fan Source Type: research

Exploring the mechanism of an active ingredient of ginger, dihydrocapsaicin, on triple negative breast cancer based on network pharmacology and < em > in  vitro < /em > experiments
Oncol Lett. 2023 Apr 3;25(5):195. doi: 10.3892/ol.2023.13781. eCollection 2023 May.ABSTRACTTo investigate the potential mechanism of ginger in the treatment of triple-negative breast cancer (TNBC) based on network pharmacology, molecular docking and in vitro cell experiments. The Traditional Chinese Medicine Systems Pharmacology Database And Analysis Platform, the Bioinformatics Analysis Tool For Molecular Mechanism Of Traditional Chinese Medicine and the HERB database and literature search were used to search for the main active compounds of ginger. Gene Ontology and Kyoto Encyclopedia of Genes and Genomes enrichment anal...
Source: Oncology Letters - April 28, 2023 Category: Cancer & Oncology Authors: Liming Luo Yuran Chen Qiuting Ma Yun Huang Tao Hong Kun Shu Zhiyong Liu Source Type: research

Analysis of transcriptome expression profiling data in oral leukoplakia and early and late ‑stage oral squamous cell carcinoma
Oncol Lett. 2023 Mar 3;25(4):156. doi: 10.3892/ol.2023.13742. eCollection 2023 Apr.ABSTRACTThe present study screened, potential prognostic biomarkers for oral carcinogenesis. The GSE85195 dataset, which consisted of oral leukoplakia (OL) and early and late-stage oral squamous cell carcinoma (OSCC) samples, was used. The differentially expressed genes (DEGs) in early OSCC vs. OL, late OSCC vs. OL and late OSCC vs. early OSCC groups were screened using the limma package in R. The Short Time-series Expression Miner software package was used to cluster DEGs with similar expression patterns in the course of disease progression...
Source: Oncology Letters - March 20, 2023 Category: Cancer & Oncology Authors: Lihui Yao Bin Guo Jiannan Wang Jiale Wu Source Type: research

Clinicopathological and prognostic value of long non-coding RNA CCAT1 expression in patients with digestive system cancer
Oncol Lett. 2023 Jan 2;25(2):73. doi: 10.3892/ol.2023.13659. eCollection 2023 Feb.ABSTRACTColon cancer associated transcript-1 (CCAT1) is known to play an important role in numerous types of human cancer, including bladder, prostate and ovarian cancer. However, a consistent perspective has not been established in digestive system cancer (DSC). To explore the prognostic value of CCAT1 in patients with DSC, a meta-analysis was performed. A systematic search of PubMed, Embase, Web of Science, China National Knowledge Infrastructure, Chinese Biological Medical Literature database, Cochrane Library and WanFang database was appl...
Source: Oncology Letters - January 23, 2023 Category: Cancer & Oncology Authors: Yue Yu Zhihua Xu Hao Ni Mengxian Jin Chen Dai Source Type: research