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Source: Annals of Clinical and Laboratory Science
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Annals of Clinical and Laboratory Science: Information for Authors
Ann Clin Lab Sci. 2023 Jul;53(4):676-677.NO ABSTRACTPMID:37625846
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Source Type: research
Suppression of Autophagy Can Augment PIK3 Inhibitor Induced Apoptosis in T Lymphoblastic Leukemia Cell Lines
CONCLUSIONS: The results demonstrated that 3-MA could suppress PI3K inhibitor-mediated activation of autophagy to promote the apoptosis of tumor cells. This discovery provided experimental support for constituting a promising strategy for T-cell acute lymphoblastic leukemia (T-ALL) therapy.PMID:37625845
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Yu Qing Dong Ni Sun Xiang Chou Yang Mu Qing He He Huang Wen Jian Guo Xiao Ji Lin Source Type: research
Linkage of Blood MALT1 with CD4+ T Cell Subset, Inflammation, Lipid, and Its Potency as a Biomarker for Predicting Major Adverse Cardiovascular Events in Coronary Heart Disease Patients
CONCLUSION: Blood MALT1 links with unbalanced CD4+ T-cell subset, elevated inflammation, and coronary-artery stenosis serving as a candidate biomarker for predicting MACE risk in CHD patients.PMID:37625844
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Lina Zhang Jianwei Li Zhijia Yang Shaowei Wang Jinjun Liu Shaohua Luan Gang Tian Source Type: research
A Case of X-Linked Adrenal Hypoplasia Congenital (AHC) Due to Large Deletion of < em > NR0B1 < /em > ( < em > DAX1 < /em > ) and Contiguous Gene
Ann Clin Lab Sci. 2023 Jul;53(4):667-670.ABSTRACTX-linked adrenal hypoplasia congenita (AHC) is caused predominantly by mutations in the NR0B1 (DAX1) gene. Among these, X-linked AHC due to a large deletion of NR0B1 is extremely rare. In Korea, the first case was reported in 2005, and there have been no further documented cases since then. Herein, we report a unique case of X-linked AHC caused by an entire gene deletion that includes the NR0B1 gene and seven other genes. A seven-day-old boy presented to a pediatric endocrine clinic with prolonged postnatal jaundice, skin hyperpigmentation, hyponatremia, and hyperkalemia, su...
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Chungwoo Shin Sung Eun Kim Cheong Jun Moon Il Han Yoo Jisook Yim Won-Kyong Cho Myungshin Kim Jung Hyun Lee Source Type: research
SHP2 Contributes to Resistance of KRAS p.G12C-Driven Lung Cancer Cells to MRTX849 by Regulating β-catenin/c-MYC Axis
CONCLUSION: SHP2 contributes to resistance of KRAS G12C-driven lung cancer cells to MRTX849 by regulating β-catenin/c-MYC axis.PMID:37625842
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Wenli Li Ya Wu Lili Dai Wei Wang Lei Zhao Source Type: research
Information About The Association of Clinical Scientists
Ann Clin Lab Sci. 2023 Jul;53(4):678.NO ABSTRACTPMID:37625841
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Source Type: research
Circular RNA SMARCA5 Promotes a Poor Prognosis and Radiotherapy Resistance for Patients with Hepatocellular Carcinoma
CONCLUSION: CircRNA-SMARCA5 is significantly increased in HCC tissues and promotes radiotherapy resistance. More importantly, higher expression level of cSMARCA5 is related to a poorer 3-year OS for patients with HCC.PMID:37625840
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Zhexing Chang Yuguo Song Fangyue Luo Xinlei Yang Yanqiu Cai Hao Guo Source Type: research
< em > Letter to Editor: < /em > Observations of Deception in Urine Drug Testing
CONCLUSION: Deception can be identified using the metabolite/parent drug ratio.PMID:37625839
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Agnes Cua Kevin Krock Richard Thomas Amadeo Pesce Source Type: research
Circ_0088212 Targeting miR-576-5p/FKBP1A Axis Inhibits Osteosarcoma Progression
CONCLUSION: This study demonstrated that circ_0088212 impedes OS progression by regulating the miR-576-5p/FKBP1A axis. These findings provide a comprehensive understanding of the role of circ_0088212 in OS tumorigenesis.PMID:37625838
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Xuan Yang Peng Sun Source Type: research
Role of MEG3 in Cellular Physiology of Atherosclerosis
CONCLUSION: Expression of MEG3 is downregulated in the patients with AS and foam cells. Overexpressed MEG3 may act as an anti-atherosclerotic factor by reducing lipid accumulation and accelerating cholesterol efflux through the miR-200b-3p/ABCA1 axis.PMID:37625837
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Yu-Ting Wu Zhi-Jun Guo Jiang-Bin Li Zhi-Rong Ye Guo-Xin Zhang Cong-Min Hong Ming Li Xin-Wen Wang Wei-Feng Xu Guan-Tao Liang Hui-Qin Lin Source Type: research
Elevated Expression of NOP16 as a Novel Prognostic Biomarker of Prostate Cancer
CONCLUSION: NOP16 may be expected to be a novel biomarker for predicting the occurrence and development of PCa, and may become a target for the treatment of PCa.PMID:37625836
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Tong Yang Fengliang Sun Changwen Zhang Zhen Wang Kuo Yang Yong Xu Qian Liu Source Type: research
miR-152-3p Inhibits Proliferation, Invasion and Autophagy in UMUC3 and TCCSUP Bladder Cancer Cell Lines via Suppressing HMGA2 Expression
CONCLUSION: miR-152-3p inhibited malignant phenotype of bladder cancer cell lines via suppressing HMGA2 expression.PMID:37625835
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Shouchun Li Minjie Pan Xiaopeng Wu Yu Bai Minjun Qi Jiasheng Chen Li Zuo Source Type: research
Acyl-CoA Medium-Chain Synthetase-3 (ACSM3) Is Regulated by Insulin Like Growth Factor 2 mRNA Binding Protein 3 (IGF2BP3) and Inhibits Proliferation, Motility and Stem Cell Properties of Breast Invasive Carcinoma
CONCLUSION: We found that ACSM3 was regulated by IGF2BP3 and attenuated BRCA proliferation, invasion and stem cell properties. The role of ACSM3 in BRCA was first revealed, which provides a novel target for treatment.PMID:37625834
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Wenjing Zhu Xiuxing Wei Meijiao Fang Source Type: research
miR-122-3p Alleviates LPS-Induced Pyroptosis of Macrophages via Targeting NLRP1
CONCLUSIONS: These results confirmed that miR-122-3p plays a crucial role in the inhibition of sepsis by suppressing macrophage pyroptosis in an NLRP1-dependent manner. Therefore, miR-122-3p presents as a promising therapeutic target for sepsis.PMID:37625833
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Min Li Longhui Hu Qiao Ke Chujun Ruan Xiaoran Liu Source Type: research
Benign Biphasic Tumors of the Mullerian Tract - a Mimic of Phyllodes Tumor. A Clinical-Pathologic Description of 21 Cases
CONCLUSION: This series adds to the growing body of literature affirming the existence of benign biphasic Mullerian polyps encountered in the endometrium and cervix that fall short of the Mullerian adenosarcoma diagnosis.PMID:37625832
Source: Annals of Clinical and Laboratory Science - August 25, 2023 Category: Laboratory Medicine Authors: Jonathan Wawire C James Sung M Ruhul Quddus Source Type: research
