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Source: Journal of Southern Medical University
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Total 14325 results found since Jan 2013.
A transcriptomic study of osteoporosis induced by ketogenic diet in mice
CONCLUSION: The differentially expressed genes and enriched pathways identified in the mouse models provide new clues for studying the molecular mechanism and prevention of KD-induced osteoporosis.PMID:37712283 | DOI:10.12122/j.issn.1673-4254.2023.08.23
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Wu Y Fan Y Ye P Li Q Zhu Z Chen B Li W Wang L Zheng Source Type: research
Manganese-based nanoparticles for chemodynamic therapy of gastrointestinal cancer
CONCLUSION: MSN@Mn-GOx nanoparticles have good chemodynamic properties and a strong anti-tumor effect and provide a potential therapeutic option for gastric cancer.PMID:37712282 | DOI:10.12122/j.issn.1673-4254.2023.08.22
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Lin M Huang J Chen X Zhou Z Zhong W Lu X Huang T Liu Source Type: research
< em > Danshenxinkun B < /em > protects human umbilical vein endothelial cells against ox-LDL-induced injury by inhibiting pyroptosis and the NF- κB/NLRP3 pathway
CONCLUSION: Danshenxinkun B alleviates ox-LDL-induced HUVEC injury possibly by suppressing pyroptosis mediated by NLRP3 inflammatory bodies and inhibiting the NF-κB/NLRP3 signaling pathway.PMID:37712281 | DOI:10.12122/j.issn.1673-4254.2023.08.21
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: H Li Y Deng T Wang K Huang C Yu C Chen Source Type: research
Socioeconomic status and cecal adenocarcinoma mortality risk: an American population-based analysis
CONCLUSION: Low socioeconomic status is associated with an increased risk of death in patients with cecal adenocarcinoma in the United States and show different distribution patterns based on population. Improving health insurance policies and strengthening psychotherapy can provide guidance for improving prognosis f cecal adenocarcinoma patients.PMID:37712280 | DOI:10.12122/j.issn.1673-4254.2023.08.20
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Shao J Lyu Source Type: research
Alveolar nitric oxide concentration has a potential value in the diagnosis and differential diagnosis of interstitial lung diseases
CONCLUSION: CaNO has a potential value in the diagnosis of ILD and differential diagnosis of CTD-ILD.PMID:37712279 | DOI:10.12122/j.issn.1673-4254.2023.08.19
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Chang M Chen H Liao H Dong S Cai Source Type: research
Physical model-based cascaded generative adversarial networks for accelerating quantitative multi-parametric magnetic resonance imaging
CONCLUSION: Compared with other existing methods, the physical model-based cascaded generative adversarial networks can reconstruct more image details and features, thus improving the quality and accuracy of the reconstructed images.PMID:37712278 | DOI:10.12122/j.issn.1673-4254.2023.08.18
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Liu Z Chu Y Zhang Source Type: research
Type 1 diabetes mellitus is likely to increase the risk of thyrotoxicdsis: a two-sample Mendelian randomization study
CONCLUSION: T1DM is likely to increase the risk of thyrotoxicosis.PMID:37712277 | DOI:10.12122/j.issn.1673-4254.2023.08.17
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: W Zhan L Zhao Source Type: research
Acetaldehyde dehydrogenase 2 ameliorates lung endothelial barrier and balances mitochondrial dynamics in mice with acute lung injury
CONCLUSION: ALDH2 can ameliorate LPSinduced lung endothelial barrier damage in ALI mice by maintaining the balance of mitochondrial dynamics and inhibiting oxidative stress, and the mechanism may be related to the Nrf2/HO-1 pathway.PMID:37712276 | DOI:10.12122/j.issn.1673-4254.2023.08.16
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Wang M Tian R Li Y Wu S Wang H L ü Z Liu Y Yu Source Type: research
A Dual-Aware deep learning framework for identification of glioma isocitrate dehydrogenase genotype using magnetic resonance amide proton transfer modalities
CONCLUSION: The proposed deep learning algorithm model constructed based on the image characteristics of the APT modality is effective for glioma IDH genotyping and identification task and may potentially replace the commonly used T1CE modality to avoid contrast agent injection and achieve non- invasive IDH genotyping.PMID:37712275 | DOI:10.12122/j.issn.1673-4254.2023.08.15
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Chu Y Qu T Zhong S Liang Z Wen Y Zhang Source Type: research
High expression of Circ-PALLD in heart failure is transcriptionally regulated by the transcription factor GATA4
CONCLUSION: Circ-PALLD is highly expressed in heart failure and can be used as a novel molecular marker for chronic heart failure, and GATA4 may play important role in regulating its transcription. Circ-PALLD points a new direction for investigating the molecular mechanism of heart failure and may also serve as a potential therapeutic target for heart failure.PMID:37712274 | DOI:10.12122/j.issn.1673-4254.2023.08.14
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Huang Z Zeng J Li R Cai W He S Hu Source Type: research
MiR-301a-5p modulates parathyroid hormone secretion in secondary hyperparathyroidism possibly by regulating calcium-sensing receptor
CONCLUSION: MiR-301a-5p affects PTH secretion in SHPT possibly by regulating the expression of CaSR.PMID:37712273 | DOI:10.12122/j.issn.1673-4254.2023.08.13
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Liu L Qian P Li J Li S Huang W Yi S Liu W Wu Source Type: research
Curcumin suppresses proliferation, migration and invasion of papillary thyriod cancer B-CPAP cells through the Keap1-Nrf2 pathway
CONCLUSION: Curcumin inhibits the proliferation, migration and invasion of papillary thyriod cancer B-CPAP cells probably via the Keap1-Nrf2 signaling pathway.PMID:37712272 | DOI:10.12122/j.issn.1673-4254.2023.08.12
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Ren M Zou X Zhu W Xu G Liu J Sun F Fan C Zhang Source Type: research
TMEM64 is highly expressed in hepatocellular carcinoma and promotes tumor cell proliferation and invasion
CONCLUSION: A high TMEM64 expression may serve as an independent risk factor for poor prognosis of HCC and promotes proliferation, migration, and invasion of HCC cells in vitro.PMID:37712271 | DOI:10.12122/j.issn.1673-4254.2023.08.11
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: D Cao J Cai Y Li R Dong Z Wang X Zuo Source Type: research
Lipocalin 2 induces self-limited inhibition of osteoblast differentiation of mesenchymal stem cells
CONCLUSION: Lcn2 is essential for normal osteogenic differentiation of MSCs, but its overexpression and excessive secretion in aging induce self-limited inhibition of osteogenic differentiation of MSCs.PMID:37712270 | DOI:10.12122/j.issn.1673-4254.2023.08.10
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Chen S Li Y Zhang W Yang T Wang Source Type: research
VDAC1 participates in house dust mite-induced asthmatic airway inflammation in mice by inducing ferroptosis of airway epithelial cells
CONCLUSIONS: VDAC1 participates in HDM-induced chronic airway inflammation in bronchial asthma by causing ferroptosis of the airway epithelial cells.PMID:37712269 | DOI:10.12122/j.issn.1673-4254.2023.08.09
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Huang L Lin H Huang H Dong Source Type: research
