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Source: Journal of Southern Medical University
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Total 14325 results found since Jan 2013.
ARHGAP21 inhibits epithelial-mesenchymal transition by inactivating the WNT signaling pathway in non-small cell lung cancer
CONCLUSION: ARHGAP21 downregulation can significantly promote the migration and metastatic ability of NSCLC possibly as a result of WNT signaling pathway activation, which reduces the ubiquitination of β-catenin by affecting the expressions of APC, GSK3β, and Axin.PMID:37712268 | DOI:10.12122/j.issn.1673-4254.2023.08.08
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Xie L Liu J Fang X Zhong J Lin F Chen Source Type: research
< em > Guizhi < /em > < em > Fuling < /em > Capsule inhibits migration and induces apoptosis of human ovarian cancer cells by regulating the NF- κB signaling pathway
CONCLUSION: GFC- medicated sera inhibits the migration ability of SKOV3/DDP cells possibly by promoting cell apoptosis and caspase 3 and CDH1 expressions, inhibiting CDH2 and NF-κB expressions, and regulating the expressions of NF-κB, CDH2 and CDH1 in the open chromatin.PMID:37712267 | DOI:10.12122/j.issn.1673-4254.2023.08.07
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Guo L Chen Q L ü R DU Q Luo Y Zhang H Bian L Han Source Type: research
Acetylcorynoline relieves 2, 4, 6-trinitrobenesulfonic acid-induced Crohn's disease-like colitis in mice by regulating intestinal epithelial cell apoptosis
CONCLUSION: Acetylcorynoline protects against TNBS-induced CDlike colitis in mice possibly by suppressing the activation of the PI3K/AKT signaling pathway, thereby inhibiting apoptosis of the intestinal epithelial cells.PMID:37712266 | DOI:10.12122/j.issn.1673-4254.2023.08.06
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Q Li J Huang Y Sun Y Xu L Wang X Zhang Y Wang Z Geng X Song L Zuo J Li J Hu Source Type: research
Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis
CONCLUSION: DRW inhibits the occurrence and progression of HCC, and this effect is mediated possibly by inducing cell cycle arrest and apoptosis.PMID:37712265 | DOI:10.12122/j.issn.1673-4254.2023.08.05
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Lan K Wang Z Lan H Zhou J Sun Source Type: research
< em > Erchen < /em > Decoction improves iron homeostasis in mice with non-alcoholic fatty liver disease by regulating iron transport capacity in the spleen
CONCLUSION: Erchen Decoction can alleviate high-fat diet-induced iron metabolism disorder by improving the iron ion transport ability of the spleen cells to delay the progression of NAFLD.PMID:37712264 | DOI:10.12122/j.issn.1673-4254.2023.08.04
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: G Deng H Jia Y Li J Li C Wu H Shi M Qin J Zhao C Liu Y Liao L Gao Source Type: research
Metformin inhibits self-renewal of colorectal cancer stem cells by inhibiting mitochondrial oxidative phosphorylation
CONCLUSION: Metformin reduces mitochondrial oxidative phosphorylation and ROS levels by inhibiting mitochondrial complex Ⅰ, thereby suppressing Wnt signaling pathway to reduce selfrenewal ability of colorectal CSCs.PMID:37712263 | DOI:10.12122/j.issn.1673-4254.2023.08.03
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: C Yan S Liu Q Song Y Hu Source Type: research
Dihydromyricetin alleviates pyroptosis and necroptosis in mice with MPTP-induced chronic Parkinson's disease by inducing autophagy
CONCLUSION: DHM can improve motor function of PD mice probably by activating autophagy to inhibit pyroptosis and necroptosis and reduce neuroinflammation.PMID:37712262 | DOI:10.12122/j.issn.1673-4254.2023.08.02
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: M Zhang Y Zhang M Niu Y Zhu S Tong X Kou Source Type: research
Sivelestat sodium for treatment of patients with COVID-19-associated acute respiratory distress syndrome in intensive care unit: a single-center retrospective cohort study
CONCLUSION: Sivelestat sodium treatment is not correlated with the reduction of mortality or length of hospital stay, but is associated with reduced serum IL-6 level in patients with COVID-19-associated ARDS.PMID:37712261 | DOI:10.12122/j.issn.1673-4254.2023.08.01
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: M Luo H Hu Y Sun X Zhao Z Zeng Y Liu G Wu Source Type: research
A transcriptomic study of osteoporosis induced by ketogenic diet in mice
CONCLUSION: The differentially expressed genes and enriched pathways identified in the mouse models provide new clues for studying the molecular mechanism and prevention of KD-induced osteoporosis.PMID:37712283 | DOI:10.12122/j.issn.1673-4254.2023.08.23
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Wu Y Fan Y Ye P Li Q Zhu Z Chen B Li W Wang L Zheng Source Type: research
Manganese-based nanoparticles for chemodynamic therapy of gastrointestinal cancer
CONCLUSION: MSN@Mn-GOx nanoparticles have good chemodynamic properties and a strong anti-tumor effect and provide a potential therapeutic option for gastric cancer.PMID:37712282 | DOI:10.12122/j.issn.1673-4254.2023.08.22
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Lin M Huang J Chen X Zhou Z Zhong W Lu X Huang T Liu Source Type: research
< em > Danshenxinkun B < /em > protects human umbilical vein endothelial cells against ox-LDL-induced injury by inhibiting pyroptosis and the NF- κB/NLRP3 pathway
CONCLUSION: Danshenxinkun B alleviates ox-LDL-induced HUVEC injury possibly by suppressing pyroptosis mediated by NLRP3 inflammatory bodies and inhibiting the NF-κB/NLRP3 signaling pathway.PMID:37712281 | DOI:10.12122/j.issn.1673-4254.2023.08.21
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: H Li Y Deng T Wang K Huang C Yu C Chen Source Type: research
Socioeconomic status and cecal adenocarcinoma mortality risk: an American population-based analysis
CONCLUSION: Low socioeconomic status is associated with an increased risk of death in patients with cecal adenocarcinoma in the United States and show different distribution patterns based on population. Improving health insurance policies and strengthening psychotherapy can provide guidance for improving prognosis f cecal adenocarcinoma patients.PMID:37712280 | DOI:10.12122/j.issn.1673-4254.2023.08.20
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Shao J Lyu Source Type: research
Alveolar nitric oxide concentration has a potential value in the diagnosis and differential diagnosis of interstitial lung diseases
CONCLUSION: CaNO has a potential value in the diagnosis of ILD and differential diagnosis of CTD-ILD.PMID:37712279 | DOI:10.12122/j.issn.1673-4254.2023.08.19
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Chang M Chen H Liao H Dong S Cai Source Type: research
Physical model-based cascaded generative adversarial networks for accelerating quantitative multi-parametric magnetic resonance imaging
CONCLUSION: Compared with other existing methods, the physical model-based cascaded generative adversarial networks can reconstruct more image details and features, thus improving the quality and accuracy of the reconstructed images.PMID:37712278 | DOI:10.12122/j.issn.1673-4254.2023.08.18
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Liu Z Chu Y Zhang Source Type: research
Type 1 diabetes mellitus is likely to increase the risk of thyrotoxicdsis: a two-sample Mendelian randomization study
CONCLUSION: T1DM is likely to increase the risk of thyrotoxicosis.PMID:37712277 | DOI:10.12122/j.issn.1673-4254.2023.08.17
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: W Zhan L Zhao Source Type: research
