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Source: Journal of Southern Medical University
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Total 14325 results found since Jan 2013.
Type 1 diabetes mellitus is likely to increase the risk of thyrotoxicdsis: a two-sample Mendelian randomization study
CONCLUSION: T1DM is likely to increase the risk of thyrotoxicosis.PMID:37712277 | PMC:PMC10505565 | DOI:10.12122/j.issn.1673-4254.2023.08.17
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: W Zhan L Zhao Source Type: research
Acetaldehyde dehydrogenase 2 ameliorates lung endothelial barrier and balances mitochondrial dynamics in mice with acute lung injury
CONCLUSION: ALDH2 can ameliorate LPSinduced lung endothelial barrier damage in ALI mice by maintaining the balance of mitochondrial dynamics and inhibiting oxidative stress, and the mechanism may be related to the Nrf2/HO-1 pathway.PMID:37712276 | PMC:PMC10505575 | DOI:10.12122/j.issn.1673-4254.2023.08.16
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Wang M Tian R Li Y Wu S Wang H L ü Z Liu Y Yu Source Type: research
A Dual-Aware deep learning framework for identification of glioma isocitrate dehydrogenase genotype using magnetic resonance amide proton transfer modalities
CONCLUSION: The proposed deep learning algorithm model constructed based on the image characteristics of the APT modality is effective for glioma IDH genotyping and identification task and may potentially replace the commonly used T1CE modality to avoid contrast agent injection and achieve non- invasive IDH genotyping.PMID:37712275 | PMC:PMC10505564 | DOI:10.12122/j.issn.1673-4254.2023.08.15
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Chu Y Qu T Zhong S Liang Z Wen Y Zhang Source Type: research
High expression of Circ-PALLD in heart failure is transcriptionally regulated by the transcription factor GATA4
CONCLUSION: Circ-PALLD is highly expressed in heart failure and can be used as a novel molecular marker for chronic heart failure, and GATA4 may play important role in regulating its transcription. Circ-PALLD points a new direction for investigating the molecular mechanism of heart failure and may also serve as a potential therapeutic target for heart failure.PMID:37712274 | PMC:PMC10505580 | DOI:10.12122/j.issn.1673-4254.2023.08.14
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Huang Z Zeng J Li R Cai W He S Hu Source Type: research
MiR-301a-5p modulates parathyroid hormone secretion in secondary hyperparathyroidism possibly by regulating calcium-sensing receptor
CONCLUSION: MiR-301a-5p affects PTH secretion in SHPT possibly by regulating the expression of CaSR.PMID:37712273 | PMC:PMC10505570 | DOI:10.12122/j.issn.1673-4254.2023.08.13
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Liu L Qian P Li J Li S Huang W Yi S Liu W Wu Source Type: research
Curcumin suppresses proliferation, migration and invasion of papillary thyriod cancer B-CPAP cells through the Keap1-Nrf2 pathway
CONCLUSION: Curcumin inhibits the proliferation, migration and invasion of papillary thyriod cancer B-CPAP cells probably via the Keap1-Nrf2 signaling pathway.PMID:37712272 | PMC:PMC10505584 | DOI:10.12122/j.issn.1673-4254.2023.08.12
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: L Ren M Zou X Zhu W Xu G Liu J Sun F Fan C Zhang Source Type: research
TMEM64 is highly expressed in hepatocellular carcinoma and promotes tumor cell proliferation and invasion
CONCLUSION: A high TMEM64 expression may serve as an independent risk factor for poor prognosis of HCC and promotes proliferation, migration, and invasion of HCC cells in vitro.PMID:37712271 | PMC:PMC10505578 | DOI:10.12122/j.issn.1673-4254.2023.08.11
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: D Cao J Cai Y Li R Dong Z Wang X Zuo Source Type: research
Lipocalin 2 induces self-limited inhibition of osteoblast differentiation of mesenchymal stem cells
CONCLUSION: Lcn2 is essential for normal osteogenic differentiation of MSCs, but its overexpression and excessive secretion in aging induce self-limited inhibition of osteogenic differentiation of MSCs.PMID:37712270 | PMC:PMC10505573 | DOI:10.12122/j.issn.1673-4254.2023.08.10
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Chen S Li Y Zhang W Yang T Wang Source Type: research
VDAC1 participates in house dust mite-induced asthmatic airway inflammation in mice by inducing ferroptosis of airway epithelial cells
CONCLUSIONS: VDAC1 participates in HDM-induced chronic airway inflammation in bronchial asthma by causing ferroptosis of the airway epithelial cells.PMID:37712269 | PMC:PMC10505576 | DOI:10.12122/j.issn.1673-4254.2023.08.09
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Huang L Lin H Huang H Dong Source Type: research
ARHGAP21 inhibits epithelial-mesenchymal transition by inactivating the WNT signaling pathway in non-small cell lung cancer
CONCLUSION: ARHGAP21 downregulation can significantly promote the migration and metastatic ability of NSCLC possibly as a result of WNT signaling pathway activation, which reduces the ubiquitination of β-catenin by affecting the expressions of APC, GSK3β, and Axin.PMID:37712268 | PMC:PMC10505574 | DOI:10.12122/j.issn.1673-4254.2023.08.08
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Z Xie L Liu J Fang X Zhong J Lin F Chen Source Type: research
< em > Guizhi < /em > < em > Fuling < /em > Capsule inhibits migration and induces apoptosis of human ovarian cancer cells by regulating the NF- κB signaling pathway
CONCLUSION: GFC- medicated sera inhibits the migration ability of SKOV3/DDP cells possibly by promoting cell apoptosis and caspase 3 and CDH1 expressions, inhibiting CDH2 and NF-κB expressions, and regulating the expressions of NF-κB, CDH2 and CDH1 in the open chromatin.PMID:37712267 | PMC:PMC10505568 | DOI:10.12122/j.issn.1673-4254.2023.08.07
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: X Guo L Chen Q L ü R DU Q Luo Y Zhang H Bian L Han Source Type: research
Acetylcorynoline relieves 2, 4, 6-trinitrobenesulfonic acid-induced Crohn's disease-like colitis in mice by regulating intestinal epithelial cell apoptosis
CONCLUSION: Acetylcorynoline protects against TNBS-induced CDlike colitis in mice possibly by suppressing the activation of the PI3K/AKT signaling pathway, thereby inhibiting apoptosis of the intestinal epithelial cells.PMID:37712266 | PMC:PMC10505581 | DOI:10.12122/j.issn.1673-4254.2023.08.06
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Q Li J Huang Y Sun Y Xu L Wang X Zhang Y Wang Z Geng X Song L Zuo J Li J Hu Source Type: research
Dealcoholized red wine inhibits occurrence and progression of hepatocellular carcinoma possibly by inducing cell cycle arrest and apoptosis
CONCLUSION: DRW inhibits the occurrence and progression of HCC, and this effect is mediated possibly by inducing cell cycle arrest and apoptosis.PMID:37712265 | PMC:PMC10505577 | DOI:10.12122/j.issn.1673-4254.2023.08.05
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: Y Lan K Wang Z Lan H Zhou J Sun Source Type: research
< em > Erchen < /em > Decoction improves iron homeostasis in mice with non-alcoholic fatty liver disease by regulating iron transport capacity in the spleen
CONCLUSION: Erchen Decoction can alleviate high-fat diet-induced iron metabolism disorder by improving the iron ion transport ability of the spleen cells to delay the progression of NAFLD.PMID:37712264 | PMC:PMC10505571 | DOI:10.12122/j.issn.1673-4254.2023.08.04
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: G Deng H Jia Y Li J Li C Wu H Shi M Qin J Zhao C Liu Y Liao L Gao Source Type: research
Metformin inhibits self-renewal of colorectal cancer stem cells by inhibiting mitochondrial oxidative phosphorylation
CONCLUSION: Metformin reduces mitochondrial oxidative phosphorylation and ROS levels by inhibiting mitochondrial complex Ⅰ, thereby suppressing Wnt signaling pathway to reduce selfrenewal ability of colorectal CSCs.PMID:37712263 | PMC:PMC10505579 | DOI:10.12122/j.issn.1673-4254.2023.08.03
Source: Journal of Southern Medical University - September 15, 2023 Category: Universities & Medical Training Authors: C Yan S Liu Q Song Y Hu Source Type: research
