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The Anesthesiology Physician-Scientist Pipeline: Current Status and Recommendations for Future Growth-An Initiative of the Anesthesia Research Council
Anesth Analg. 2023 Oct 1;137(4):728-742. doi: 10.1213/ANE.0000000000006520. Epub 2023 Sep 5.ABSTRACTThe limited number and diversity of resident physicians pursuing careers as physician-scientists in medicine has been a concern for many decades. The Anesthesia Research Council aimed to address the status of the anesthesiology physician-scientist pipeline, benchmarked against other medical specialties, and to develop strategic recommendations to sustain and expand the number and diversity of anesthesiology physician-scientists. The working group analyzed data from the Association of American Medical Colleges and the Nationa...
Source: Anesthesia and Analgesia - September 15, 2023 Category: Anesthesiology Authors: Charles W Emala Vivianne L Tawfik Meghan B Lane-Fall Paloma Toledo Cynthia A Wong Monica S Vavilala Lee A Fleisher Margaret Wood Source Type: research
The use and acceptability of preprints in health and social care settings: A scoping review
ConclusionsPreprints provide opportunities for rapid dissemination but there is a need for clear policies and guidance from journals, publishers, and funders. Cautionary measures are needed to maintain the quality and value of preprints, paying particular attention to how findings are translated to the public. More research is needed to address some of the uncertainties addressed in this review.
Source: PLoS One - September 15, 2023 Category: Biomedical Science Authors: Amanda Jane Blatch-Jones Source Type: research
Time-efficient, high-resolution 3T whole-brain relaxometry using 3D-QALAS with wave-CAIPI readouts
CONCLUSION: Three-dimensional QALAS enhanced with wave-CAIPI readouts enables time-efficient, full-brain quantitative T1 , T2 , and PD mapping at 1.15 mm3 in 3 min at R = 3 × 2 acceleration. The quantitative maps obtained from the accelerated wave-CAIPI 3D-QALAS protocol showed very similar values to those from the standard 3D-QALAS (R = 2) protocol, alluding to the robustness and reliability of the proposed method.PMID:37705496 | DOI:10.1002/mrm.29865
Source: Magnetic Resonance in Medicine - September 14, 2023 Category: Radiology Authors: Jaejin Cho Borjan Gagoski Tae Hyung Kim Fuyixue Wang Mary Kate Manhard Douglas Dean Steven Kecskemeti Arvind Caprihan Wei-Ching Lo Daniel Nico Splitthoff Wei Liu Daniel Polak Stephen Cauley Kawin Setsompop Patricia Ellen Grant Berkin Bilgic Source Type: research
Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers
Biomaterials. 2023 Sep 6;302:122318. doi: 10.1016/j.biomaterials.2023.122318. Online ahead of print.ABSTRACTNanoparticle-based drug delivery systems (DDS) have shown promising results in reversing hepatic fibrosis, a common pathological basis of chronic liver diseases (CLDs), in preclinical animal models. However, none of these nanoparticle formulations has transitioned to clinical usage and there are currently no FDA-approved drugs available for liver fibrosis. This highlights the need for a better understanding of the challenges faced by nanoparticles in this complex disease setting. Here, we have systematically studied ...
Source: Biomaterials - September 14, 2023 Category: Materials Science Authors: Arunpandian Balaji Craig A Bell Zachary H Houston Kim R Bridle Berit Genz Nicholas L Fletcher Grant A Ramm Kristofer J Thurecht Source Type: research
Time-efficient, high-resolution 3T whole-brain relaxometry using 3D-QALAS with wave-CAIPI readouts
CONCLUSION: Three-dimensional QALAS enhanced with wave-CAIPI readouts enables time-efficient, full-brain quantitative T1 , T2 , and PD mapping at 1.15 mm3 in 3 min at R = 3 × 2 acceleration. The quantitative maps obtained from the accelerated wave-CAIPI 3D-QALAS protocol showed very similar values to those from the standard 3D-QALAS (R = 2) protocol, alluding to the robustness and reliability of the proposed method.PMID:37705496 | DOI:10.1002/mrm.29865
Source: Magnetic Resonance in Medicine - September 14, 2023 Category: Radiology Authors: Jaejin Cho Borjan Gagoski Tae Hyung Kim Fuyixue Wang Mary Kate Manhard Douglas Dean Steven Kecskemeti Arvind Caprihan Wei-Ching Lo Daniel Nico Splitthoff Wei Liu Daniel Polak Stephen Cauley Kawin Setsompop Patricia Ellen Grant Berkin Bilgic Source Type: research
