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Drug: Dexamethasone
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Total 6562 results found since Jan 2013.
Observation of the Curative Effect of the Dexamethasone Vitreous Cavity Implant for the Treatment of Irvine-Gass Syndrome
CONCLUSION: The dexamethasone vitreous cavity implant (Ozurdex) is a safe and effective treatment, which can effectively improve patient's visual acuity and reduce macular edema associated with cataract surgery.PMID:37711084 | DOI:10.3967/bes2023.084
Source: Biomedical and Environmental Sciences : BES - September 15, 2023 Category: Biomedical Science Authors: Yu Mao Li Qin Gao Li Yun Jia Si Meng Hou Yuan Yuan Xiao Xi Wen Ji Shuang Wang Source Type: research
Resistance exercise alleviates dexamethasone-induced muscle atrophy via Sestrin2/MSTN pathway in C57BL/6J mice
CONCLUSION: Taken together, our results indicated that Sestrin2 may serve as an effective molecule that mimics the protective effect of resistance exercise on dexamethasone-induced muscle atrophy.PMID:37709247 | DOI:10.1016/j.yexcr.2023.113779
Source: Experimental Cell Research - September 14, 2023 Category: Cytology Authors: Yang Yang Xuege Yang Yating Huang Sujuan Liu Yanmei Niu Li Fu Source Type: research
Prognostic factors for poor outcomes in patients with severe COVID-19 treated with remdesivir plus dexamethasone in Taiwan
CONCLUSION: High disease severity on admission and delayed initiation of remdesivir therapy were associated with poor outcomes in COVID-19 patients treated with remdesivir and dexamethasone.PMID:37696685 | DOI:10.1016/j.jmii.2023.08.008
Source: Journal of Microbiology, Immunology, and Infection - September 11, 2023 Category: Microbiology Authors: Yi-Hsuan Lai Yi-Chih Lee I-Ren Chen Shih-Neng Lin Yuh-Lih Chang Chih-Chia Lu Ping-Feng Wu Yi-Tsung Lin Source Type: research
Klf9 plays a critical role in GR -dependent metabolic adaptations in cardiomyocytes
We examined the role of Krüppel-like factor 9 (Klf9), an early direct target of GR in cardiomyocytes. Klf9-ChIPseq identified 2150 genes that showed an increase in Klf9 binding in response to Dex. Transcriptome analysis of Dex treated cardiomyocytes with or without knockdown of Klf9 revealed differential regulation of 1777 genes, of which a reversal in expression is seen in 1640 genes with knockdown of Klf9 compared to Dex. Conversely, only 137 (~8%) genes show further dysregulation in expression with siKLf9 as seen with Dex treated cardiomyocytes. Functional annotation identified genes of metabolic pathways on the top of...
Source: Cellular Signalling - September 10, 2023 Category: Cytology Authors: Chandni Thakkar Saleena Alikunju Nandita Niranjan Wajiha Rizvi Ali Abbas Maha Abdellatif Danish Sayed Source Type: research
Unveiling pro-angiogenesis and drug delivery using dual-bio polymer with bio-ceramic based nanocomposite hydrogels
Chemosphere. 2023 Sep 8:140131. doi: 10.1016/j.chemosphere.2023.140131. Online ahead of print.ABSTRACTIn regenerative medicine, blood vessel development is of utmost importance as it enables the restoration of blood flow to tissues, and facilitate rapid vascularization in clinical tissue-engineered grafts. Herein, we fabricate the nanocomposite hydrogels from BG, alginate, Polyethylene glycol (PEG) and Dexamethasone (DEX) for the dual applications of drug delivery and angiogenesis assay. The hydrogels were fabricated through cross-linking approach and termed as alginate/PEG (A), alginate/PEG/clinophosinaite (AC), and algin...
Source: Chemosphere - September 10, 2023 Category: Chemistry Authors: K Elakkiya P Bargavi S Balakumar Source Type: research
Topical formulations of Aprepitant are safe and effective in relieving pain and inflammation, and drive neural regeneration
CONCLUSIONS: Aprepitant X formulation is a promising candidate for the treatment of pain associated with inflammation of the ocular surface.PMID:37690516 | DOI:10.1016/j.jtos.2023.09.004
Source: The Ocular Surface - September 10, 2023 Category: Opthalmology Authors: Filippo Bonelli Ibrahim Demirsoy Romina Mayra Lasagni Vitar Philippe Fonteyne Giulio Ferrari Source Type: research
