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What evidence for a cholera vaccine? Jaime Ferr án's submissions to the Prix Bréant
This article analyses how the French Academy of Sciences assessed Jaime Ferrán's cholera vaccine submitted for the Prix Bréant in the 1880s. Ferrán, a Spanish independent physician, discovered the treatment in 1884 and tried it on thousands of patients during the cholera outbreak in Valencia the following year. His evaluation sparked a controversy in Spain and abroad on the vaccine's efficacy. The Bréant jury did not see any evidence for it in Ferrán's submission, a decision usually interpreted in terms of French scientific nationalism (or simple chauvinism): an outsider from the scientific periphery could not be awar...
Source: Medical History - September 19, 2023 Category: History of Medicine Authors: Clara Uzcanga David Teira Source Type: research
Personal exposure to radiofrequency electromagnetic fields in various occupations in Spain and France
CONCLUSION: We conducted personal RF-EMF measurements among workers in various occupations in Spain and France. Overall, RF-EMF exposure ≥1 % ICNIRP was infrequent, despite some intermittent exposures ≥100% observed among workers in some occupations.PMID:37722304 | DOI:10.1016/j.envint.2023.108156
Source: Environment International - September 18, 2023 Category: Environmental Health Authors: Maxime Turuban Hans Kromhout Javier Vila Miquel Vallbona-Vist ós Isabelle Baldi Michelle C Turner Source Type: research
The risk of road traffic crashes for occupational drivers: A responsibility study with comparison to the general population
CONCLUSION: On-duty drivers showed lower risk of responsibility for an accident than other drivers. However, on-duty drivers on temporary or work/study contracts, who are usually not subject to specific regulations, showed higher risk, and should be the subject of particular attention regarding occupational risk prevention.PMID:37718828 | DOI:10.3233/WOR-220578
Source: Work - September 18, 2023 Category: Occupational Health Authors: Nicolas Guibert Jean-Louis Martin Blandine Gadegbeku Emmanuel Lagarde Barbara Charbotel Source Type: research
Medico-economic impact of thoracoscopy versus thoracotomy in lung cancer: multicentre randomised controlled trial (Lungsco01)
CONCLUSIONS: Given our results, the economic efficiency of video-thoracoscopy at 30 days remains fragile at a willingness-to-pay threshold of €25,000/QALY. The economic efficiency is not established beyond that time horizon. The acceptability curves given will allow decision-makers to judge the probability of efficiency of this technology at other willingness-to-pay thresholds.TRIAL REGISTRATION: NCT02502318.PMID:37723516 | DOI:10.1186/s12913-023-09962-y
Source: Cell Research - September 18, 2023 Category: Cytology Authors: Anne-Laure Soilly Ludwig Serge Aho Gl élé Alain Bernard Halim Abou Hanna Marc Filaire Pierre Magdaleinat Charles Marty-An é Fran çois Tronc Renaud Grima Jean-Marc Baste Pascal-Alexandre Thomas Bertrand Richard De Latour Arnaud Pforr Pierre-Beno ît Pa Source Type: research
Genetic analysis of geometric morphometric 3D visuals of French jumping horses
CONCLUSIONS: The main application of 3D morphometric analysis is the ability to define the estimated breeding value (EBV) of a sire based on the shape of its potential progeny, which is easier for breeders to visualize in a single synthetic image than a full description based on linear profiling. However, the acceptance of these new phenotypes by breeders and the complex nature of summarized shapes may be challenging. Due to the low genetic correlations of the summarized shapes with jumping performance, the methodology did not allow indirect performance selection criteria to be defined.PMID:37723416 | DOI:10.1186/s12711-023-00837-8
Source: Genet Sel Evol - September 18, 2023 Category: Genetics & Stem Cells Authors: Anne Ricard Nathalie Crevier-Denoix Philippe Pourcelot Harmony Crichan Margot Sabbagh Bernard Dumont-Saint-Priest Sophie Danvy Source Type: research
Personal exposure to radiofrequency electromagnetic fields in various occupations in Spain and France
CONCLUSION: We conducted personal RF-EMF measurements among workers in various occupations in Spain and France. Overall, RF-EMF exposure ≥1 % ICNIRP was infrequent, despite some intermittent exposures ≥100% observed among workers in some occupations.PMID:37722304 | DOI:10.1016/j.envint.2023.108156
Source: Environment International - September 18, 2023 Category: Environmental Health Authors: Maxime Turuban Hans Kromhout Javier Vila Miquel Vallbona-Vist ós Isabelle Baldi Michelle C Turner Source Type: research
The risk of road traffic crashes for occupational drivers: A responsibility study with comparison to the general population
CONCLUSION: On-duty drivers showed lower risk of responsibility for an accident than other drivers. However, on-duty drivers on temporary or work/study contracts, who are usually not subject to specific regulations, showed higher risk, and should be the subject of particular attention regarding occupational risk prevention.PMID:37718828 | DOI:10.3233/WOR-220578
Source: Work - September 18, 2023 Category: Occupational Health Authors: Nicolas Guibert Jean-Louis Martin Blandine Gadegbeku Emmanuel Lagarde Barbara Charbotel Source Type: research
High flow nasal oxygen in frail COVID-19 patients hospitalized in intermediate care units and non-eligible to invasive mechanical ventilation
CONCLUSIONS: We suggest that HFNO is an option in non-ICU skilled units for older and frail patients with a severe COVID-19 pneumonia, otherwise non-suitable for intensive care and mechanical ventilation. Observation of clinical signs of respiratory failure before HFNO initiation was associated with mortality.PMID:37717386 | PMC:PMC10195878 | DOI:10.1016/j.resmer.2023.101026
Source: Respiratory Care - September 17, 2023 Category: Respiratory Medicine Authors: Corentin Meersseman Emmanuel Grolleau Nathalie Freymond Florent Wallet Thomas Gilbert Myriam Locatelli-Sanchez Laurence G érinière Emilie Perrot Pierre-Jean Souquet Clara Fontaine-Delaruelle Jean-St éphane David S ébastien Couraud Source Type: research
Primary care physicians' experience of caring for children with parents with mental health illness: a qualitative study among French general practitioners and paediatricians
CONCLUSION: Practitioners describe a parent-doctor relationship at risk, which is underpinned by the fear of care placement. This study illustrates the need to strengthen multidisciplinary work by promoting interprofessional exchanges, in order to improve the experience of practitioners in this care process. Addressing practitioners' fear of discussing parental psychiatric illness is very important, so as not to delay the implementation of preventive actions that are likely to improve the developmental prognosis for children.PMID:37718455 | DOI:10.1186/s12875-023-02145-y
Source: Primary Care - September 17, 2023 Category: Primary Care Authors: C écile Ribette Lucie Rosenthal Jean-Philippe Raynaud Ludivine Franchitto Alexis Revet Source Type: research
Interleukin-37 gene expression is down-regulated in patients with acute myeloid leukemia and shown to be affected by CD14 and HLA-DR immunophenotypes
In conclusion, IL37 mRNA expression was down-regulated in AML patients, especially females, and those with the FAB M4 type and the WHO PML-RARA type. This expression may be affected by the immunophenotypic markers CD14 and HLA-DR.PMID:37716188 | DOI:10.1016/j.cyto.2023.156368
Source: Cytokine - September 16, 2023 Category: Molecular Biology Authors: Mustafa A Bashi Ali H Ad'hiah Source Type: research
